THE USE OF COCAINE IN NERVOUS AFFECTIONS.

At the recent meeting of the American Neurological Association, Dr. J. K. Bauduy, of St. Louis, read a paper in which he recounted his experience with the use of cocaine in the treatment of certain forms of psychical disturbance. We expect to publish Dr. Bauduy's paper shortly. In the mean time, we would call attention to a letter which has been shown us, written by Dr. L. Bremer, of St. Louis, from which we make the following extracts: "Dr. Bauduy, of this city, has been using the cocaine in cases of melancholia with the happiest results. During a recent visit at St. Vincent's Hospital I was, by the kindness of the doctor, afforded an opportunity of witnessing the rapid and wonderful effect which the hypodermic injection of one grain of the drug produced in the affection named. W. H., aged seventeen, who was under my treatment before his admission to the hospital, for hebephrenia, and whose mental state I am thoroughly familiar with, was, on our visit, found in a condition of great depression. Although he knew me well, he refused to speak to or recognize me. The expression of his face was that of utter dejection, despair, and disgust. All efforts to elicit an answer to my questions failed; he remained wrapped up in a sullen silence. The injection of one grain of cocaine changed the scene as by magic. Four minutes after the introduction of the drug the patient began to talk; the spell was broken, and he conversed freely and intelligently on the nature of his trouble. The almost mathetical precision of the effect of the remedy could only be compared to that of morphine in certain nervous affections.

"The second case in which the cocaine was tried in my presence. and yielded a like brilliant result, was that of a young man suffering from a severe form of melancholia combined with a refusal to take nourishment. Five minutes after the administration of the drug he became quiet and partook readily of the nourishment offered him. This patient would never eat except when under the influence of the drug; it was employed for the first time when he was approaching inanition, to avert which the feeding-tube was thought of as a last resort. To my knowledge, Dr. Bauduy has been the first to try cocaine in melancholia."

Dr. Bauduy seems to have been the first also to suggest the use of cocaine for the morning sickness of pregnancy. An interesting account of Dr. Scenck's experience with the remedy for that distressing condi

tion will be found in the report of the proceedings of the St. Louis Medico-Chirurgical Society, published in the "St. Louis Courier of Medicine" for May, where it expressly stated that the cocaine was used at the suggestion of Dr. Bauduy.-N. Y. Med. Jour..

MISCELLANEOUS NOTES.

Try P. D. & Co.'s Chor-Anodyne.

Our medical societies have adjourned for the summer.

Chapman, Green & Co.'s Nitrogenized Iron gives most excellent satisfaction.

Lactopeptine is of great advantage for the many troubles incident to indigestion.

We are reliably informed that the State Hospital at Boulder is used to stable a mule.

Succus Alternans, (McDade) Eli Lilly & Co., is perhaps the best general alterative known.

Dr. L. C. Winsor, of New York, has been appointed resident physician to the county Hospital.

P. D. &. Co. Fld. Ex. Euphorbia Pilulifera has a most marked and beneficial effect on all dyspnoea's.

Mr. Lenox Brown, of London, holds that alcoholic stimulants have a most injurious effect upon the larynx and pharynx.

Permanent obliteration in arteries, after ligature takes place in from four to seven days, in veins in from three to four days.

The German Imperial Board of Health will soon publish a weekly journal for the record of its statistics, reports and papers.

After several years trial we have no hesitation in saying that the best and most reliable preparation of hydrastis is that of the Wm. S. Merrell Chemical Co.

Dr. Thomas H. Hawkins is preparing a Medical Directory of the Colorado Physicians. Please send in your name, address, college and date of graduation.

Dr. John V. Shoemaker, of Philadelphia, and Dr. A. Jacobi, of New York, do not agree upon the subject of the international congress and the new code.

The death of Dr. G. B. Soresina, the distinguished Italian syphili

dologist, is announced in the "Gazzetta degli Ospitali." The deceased was eighty-three years of age.

A report is made of a case of sudden death due to the injection of a stream of cold water against the cervex of a pregnant woman, for the purpose of inducing abortion. Did shock induce the death, or what?

Dr. Belfry, of London, Ont., reports the birth of a child 181⁄2 pounds at birth, and measuring 2334 inches in length. He also reports the case of a woman, forty-two years old, who is cutting two new incisor teeth.

W. R. Warner & Co. have received the first premium at the World's Exposition, New Orleans, for great uniformity and solubility for their sugar-coated pills. This is the ninth world's fair prize which attests. their excellence.

Dr. Detmold, of New York, says that he has never seen the œdema over the anterior surface of the tibia, in cases of periostitis of that bone from syphilis, disappear. Hence, he regards this oedema as a character

istic mark of syphilis.

Lawson Tait says: "the amount of worry which is given by every case of hystertectomy, even when successful, is such as to be almost be yond the recompense of any fee; and the disappointment inflicted by every death is quite indescribable." We wonder how many Colorado

physicians suffer under these trying circumstances.

A young physician who has just established himself and has very little practice, is noted for his braggadocio. One of the older physicians, meeting him on the street yesterday, asked him how he was coming on. "I've got more than I can attend to,' was the boastful reply, "I had to get out of my bed five times last night." "Why don't you buy some insect poison?" asked the old doctor.

Ex.

A prominent physician in a neighboring city received the following note from a lady a few days since: "Dear doctor; please come to sce my brother at once, and bring your urethra with you. Respectfully, The doctor answered the call and carried a catheter.Atlan Med. and Surg. Jour.

Mrs.

The Royal Academy of Medicine of Rome according to the "Lancet," has admitted the British delegates to the recent International Sanitary Conference, Sir Guyer Hunter, Dr. Thorne, Sir Joseph Fayrer, and Dr. T. Lewis, as honorary fellows.

Nothing can be devised that will answer the purposes for which intended more thoroughly than Melliers Standard Saddle-Bags and Buggy

Cases. Send for descriptive circular, and remember that upon receipt of price the proprietors will deliver to any express office in this country, charges prepaid.

The fifty-third annual meeting of the British Medical Association will be held at Cardiff, on Tuesday, Wednesday, Thursday, and Friday, July 28th, 29th, 30th, and 31st, 1885. Presideut, James Cuming, M. D., F.K.Q.C.P., Belfast. President-elect, W. T. Edwards, M. D., F.

R. C. S., Cardiff.

Dr. Fleischl, of Vienna, is said to have found in cocaine a rapid and satisfactory cure for alcoholism, morphinism, and allied habits. The nervous symptoms which rise upon either withdrawing the drug abruptly or by degrees are treated by the hypodermic administration of the muriate of cocaine. It is claimed that in ten days a cure may be effected. The dose is from a quarter to half a grain dissolved in water.

An able army surgeon says that the presence of a young woman among wounded soldiers is detrimental, by keeping them in a state of sexual excitement. Army men prefer the old regimental orderlies. If this be true is the presence of female nurses in the men's wards of a general hospital desirable? If the facts quoted are correct the matter deserves consideration at the hands of hospital authorities.-Det. Lancet.

The death of Dr. Josph Estabrook, of Rockland, Me., took place last Sunday. The deceased was eighty seven years of age, and is said to have been the oldest graduate of Williams College at the time of his death. He was an alumnus of the Harvard Medical School. Many years ago he was the demonstrator of anatomy in the Medical School of Maine, and had been president of the Maine Medical Association.

WAIFS AND STRAYS.

APPLICATION FOR NEURALGIA.-Equal parts of oil of cajeput and oil of peppermint, applied locally, relieve the pain of neuralgia and gout. SAFE CROTON OIL.-If croton oil be shaken up with alcohol, its irritating properties are dissolved, and it acts as a powerful but benign purgative.

THE NEW YORK POLYCLINIC.-Dr. M. Allen Starr has been elected professor of diseases of the mind and nervous system in the New York Polyclinic.

FOR DYSMENORRHOEA.-Dysmenorrhoea is quickly relieved by thirty minim doses of liquid extract of hamamelis virginica in a little sweetened water, three times a day.

FOR SORE THROAT.-Strong, black tea, used cold, forms an excellent prophylactic against common "sore-throat." A solution of table salt, one drachm to a pint, is also efficacious.

THE GLASGOW OBSTETRICAL AND GYNECOLOGICAL SOCIETY. -Our English exchanges announce the organization of a society with this title in Glasgow, with Professor Leishman for president.

TO ABORT MAMMARY ABSCESS.-Quinine, in doses of ten grains every twelve hours, will frequently abort threatened mammary abscess. It is not, however, advisable in those cases immediately following labor.

A READY METHOD OF STOPPING HICCOUGH.-A Brazillian physician, Dr. Ramos ("Bull. gen. de therap."), states that refrigeration of the lobe of the ear will stop hiccough, whatever its cause may be. Very slight refrigeration will answer-the application of cold water or even of saiiva being sufficient.

THE "INTERNATIONAL JOURNAL OF THE MEDICAL SCIENCES.-Beginning with the issue for January, 1886, according to the "British Medical Journal," this will be the title of the "American Journal of the Medical Sciences," Dr. Hayes continuing as the American editor, and Mr. Malcolm Morris being the European editor.

ANISIC ACID As an Antipyretic.—This substance (Ibid), obtained by the oxidation of oil of anise, takes the form of colorless prismatic crystals soluble in alcohol and in ether. It has antiseptic properties, also an antipyretic action analogous to that of salicylic acid. It should be used with caution, as large doses injected into the veins of various animals have caused epiletoid convulsions.

Treatment of ASTHMA.-Dr. Germain See (Paris) advocates the treatment of asthma, and allied disorders by the inhalation of pyridine. About a drachm is to be placed on a plate in a closed room, and the patient breathes the impregnated air, for twenty minutes, three times daily. It can be immediately traced in the urine. The dysponcea and oppression are at once relieved, and there are no unpleasant after effects, except relaxation of muscular power. Calm sleep is also induced. Inhalation

is far preferable to subcutaneous injection.

HAY FEVER.-Dr. Sajous gives the following definition of hay fever: "An affection characterized by periodical attack of acute rhinitis complicated sometimes with asthma, occurring as a result of a special susceptibility on the part of certain individuals to become influenced by certain substances, owing to a deranged state of the nerve centers. It man