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corpuscular improvement-an average of 42 per cent. The subjective symptoms of muscular weakness with mental lethargy, were most pronounced. She had been unable to take food, except of fluid character, and in very small quantities, for several weeks. Appetite was totally absent, and milk and broths, even in moderate amounts, occasioned gastric distress and were frequently vomited. She had at times paroxysms of pain resembling gastralgia. Constipation was a marked feature. Physical examination of the thorax revealed loud, systolic, blowing murmurs-hæmic-over the entire precordia, most pronounced at the base of the heart and in the carotids. There was prescribed, in addition to rest, frequent bathing, peptonized milk and Blaud's mass in ascending doses. Two weeks' treatment by these measures failed either to increase the proportion of hæmoglobin or relieve the general weakness and marked disturbances of the gastric functions. She was then placed on Gray's Glycerine Tonic Compound, two drachms four times daily, and the iron was discontinued. At the expiration of seven days she had desire for food, which was apparently digested and assimilated. She was given fluid extract of cascara sagrada in fifteen-drop doses at bedtime, in order to overcome constipation. Her appetite gradually returned; she was able after two weeks to take lighter articles of diet-eggs, toast, scraped raw meat-and she had consequently gained strength. Treatment by rest, bathing and the administration of Gray's Glycerine Tonic Comp, was contined for eight weeks, at which time she had gained fourteen pounds in weight, was entirely free from gastralia and the symptoms of atonic dys pepsia, and her hæmoglobin had increased 82 per cent. She had had slight menstrual show, and she is now so far conva lesced that she is able to indulge in a fair amount of mental and physical exertion without experiencing undue fatigue.

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Fo doubt many of our Doctor friends will recognize the following from Chas. B. Forsyth, M. D., (Belvue Hospital Med: ical College, New York City), dated Alexandria Bay, N. Y., Jan. 6th, 1903-an expression which will, in many instances, recall their own experience. He says: "I can say no more than that I have used Antikamnia Tablets since I began prac

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ANTIPHLOGISTINE VS. PNEUMONIA.

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The action of Antiphlogistine is dependent upon well defined physiological laws-that a most important reflex association exists between the vessels of the skin and the underly. ing tissue; that, when the superficial blood-vessels dilate the deep-seated ones contract, Continuous stimulation of the cutaneous reflex maintains continued relief by persistent contraction of vessels in the inflamed area of lung tissue. Such governing action prohibits extension of the products of inflam. mation through infiltration by affecting rapid absorption and elimination of toxines. The infected area becomes self-limited as the adjacent blood-vessels supply well aerated blood to compensate for the surcharged venous blood due to pulmonic consolidation, Under reflex control Antiphlogistine resolves hepatization of lung tissue and through osmosis and dialysis assists the superficial blood-vessels and lymph spaces to drain the hyperaemic parts by direct capillarity. Lessened bloodpressure prevents administration of whipping medication to the over-burdened heart.

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In calling attention to the disease known as anchylostom. iasis or Uncinariasis, I wish to state at the outset that most of my information regarding the disease was procured from a pamphlet issued by the Department of Agriculture, and written by Mr. C. Wardell Stiles, a zoologist employed in the Bureau of Animal Industry. In his introduction he makes the statement: "There is nothing strange in the fact that a number of cases (about thirty-five since 1893) of Uncinariasis in man have recently been diagnosed in this country."

Now when we take into consideration the common occurrence of the disease in the sandy regions of Alabama, it is surprising that only one case has heretofore been reported from this State. My attention was first called to this disease by reading accounts of the worm in sheep and dogs, and I procured the pamphlet which treats on the disease in man.

Text books on pathology devote but a small space to the subject, dismissing it as though it were a rare condition, while right under our eyes the Hook worm is the cause of the severe cases of anemia in children and young people, which cannot be attributed to the already recognized organic diseases. are accustomed to refer to these pale anemic stunted children, as dirt eaters, when in reality, I believe the dirt eating is rather a symptom of the disease than the cause of the condition. Some time ago I was called in consultation by Dr. S. S. Pugh to see a family of children residing near the Barker Cotton Mill, three miles north of the city, and as we could not find

*Read before the Mobile County Medical Society, February 28, 1903.

any other cause for the profound anemia and dropsical condition of the legs and feet, we had Dr. E. D. Bondurant make a microscopical examination of the stools of these children. There was no difficulty in recognizing the eggs of the Hook worm in every specimen examined.

The important symptoms are: Anemia, the skin often assuming a pale greenish yellow appearance. Circulatory disturbances, such as are found in all grave anemias-and often an hemic murmur can be heard over the precardial region. Pulsating carotids are seen in nearly every case, and, the patients often complain of dizziness. Colicky pains in the abdomen, great weakness, frequently marked emaciation, while at the same time the abdomen seems to be well nourished. Constipation or diarrhea may be present, and the stools are sometimes brownish, which gives the appearance of containing blood. In recent cases of infection, there is as a rule edema, usually more marked in the left leg and foot than in the right. There is only one way to make a positive diagnosis and this is to find the eggs or the parasites in the stools. The patients frequently have enormous appetites.

The disease is known by a number of different names, among the most common being anchylostomiasis, brick-makers' anemia, Egyptian chlorosis, miners' anemia, or miners' cachexia, Porto Rican anemia, tunnel anemia and Hook worm disease.

According to the international law of priority, which is recognized by biologists, Uncinariasis is declared to be the proper name for the disease, because the Hook worm does not belong to the genus anchylostomia (1843) but the worm is now generally supposed to be congeneric with the uncinaria first described in 1789; therefore, we will speak of the disease as uncinariasis or uncinariosis.

The parasite which causes Uncinariasis belongs to the nematode family strongylidae, and is consequently a thread-like round worm, and varying in length from one-quarter of an inch to one inch. It can be seen with the naked eye, and advantage can be taken of this fact by practitioners who are away from medical centers, or who do not possess a microscope. It is estimated that there may be from 500 to 3,000 worms in each individual infected with this disease.

The eggs are microscopic in size, and can be readily seen with a one-third inch Bausch and Lomb objective. They are about twelve times the diameter of a human blood corpuscle,

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