FINDLEY'S GYNECOLOGICAL DIAGNOSIS.

A Treatise on the Diagnosis of Diseases of Women. For Students and Prac titioners. By Palmer Findley, B.S., M.D., Assistant Professor of Obstetrics and Gynecology, Rush Medical College in affiliation with the University of Chicago; Assistant Attending Gynecologist to the Presby terian Hospital, Chicago. In one octavo volume of 588 pages, illustrated with 222 engravings in the text and 59 plates in colors and monochrome Cloth, $4.75, net; leather, $5.75, net. Lea Brothers & Co., Publishers, Philadelphia and New York, 1905.

In no department of medicine are cases more numerous, important and oftentimes obscure than in gynecology, but fortunately there is no class of diseases more open to positive and clear diagnosis by modern methods. Until the appearance of Dr. Findley's work there was no book in English which covered the subject.

The importance of the subject is evident, as correct diagnosis leads directly to successful treatment. In its first edition this excellent work was promptly accepted as the authority. Dr. Findley covers the subject fully and practically, and bearing in mind the needs of both students and practitioners explains the most modern views and methods simply and will careful details, using black and colored illustrations freely. The first edition of this work has already been exhausted, and the author has utilized the opportunity to revise the volume thoroughly, bringing it in every part welul up to date. An addition of nearly 100 pages of text, 12 engravings and 14 colored plates has been necessary to present the important growth of the subject during the short interval since its first edition. The new matter on Blood Examination, Differential Diagnosis, Bacteriological Examinations, etc., much enhances the value of one of the most helpful books ever offered to the medical public.

GRAY'S ANATOMY.

Messrs. Lea Brothers & Co. have pleasure in announcing a new edition of Gray's Anatomy, to be published about midsummer, and embodying nearly two years of labor on the part of the editor, J. Chalmers DaCosta, M.D., of Philadelphia, and a corps of special assistants.

Commensurately with the importance of the leargest selling medical work ever published, this new edition will present a revision so thorough and searching that the entire book has been reset in new type. In addition to the changes necessary to bring it abreast of the most modern knowledge of its subject, several important alterations have been made with the view of adapting it still more closely to present-day teaching methods, and in fact to anticipate the trend of anatomical work and study.

Thus, while the older nomenclature is used, the new names (B.N.A.) follow in brackets; the section on Embryology and Histology at the back of the present "Gray" has been distributed throughout the new edition in the shape of embryological, histological and biological references and paragraphs bearing directly on the part under consideration, thus contributing to a better and easier understanding.

The illustrations have come in for their full share of the general revision, so that at this writing more than 400 new and elaborate engravings in black and colors have been prepared. "Gray" has always been noted for its richness of illustration, but the new edition far exceeds anything that has hitherto been attempted.

No medical text-book has ever approached "Gray" in sturdy longevity and accumulaing strength. Nothwithstanding the many would-be competitors which during nearly fifty years have periodically appeared and endeavored to share its ever-increasing popularity, this wonderful creation of a genius who lived barely long enough to realize that his work was done how well he never knew-goes on and on, each succeeding year bringing new friends and strengthening the fealty of the old.

The editor and publishers have spared neither labor nor expense to keep "Gray" at the forefront of anatomical knowledge, and there seems to be no reason to doubt that its next fifty years will pass as smoothly and as successfully as have those past.

MISCELLANEOUS.

WORDS OF APPRECIATION.

The following letter, relating to the treatment of opium and other addictions, will interest many. It is addressed to our old friends, The Antikamnia Chemical Company, and reads:

"Gentlemen.-Illness, dating from the very day of my former letter must be my plea for my silence and my seeming indifference to your courtesy, and your exceptional kindness in sending me your little 'Vest-PocketBox.' I want you to feel that I sincerely appreciate your goodness in this little matter. I am in charge of the Woolley Sanatorium, an institution conducted exclusively for the cure of opium and other drug addictions, and am using Antikamnia Tablets extensively after withdrawing morphia, and I am free to say that I do, in reality, regard your product as 'A Succedaneum for Morphia.'

“Our institution is probably the largest of its kind in the South, and if may views should prove of value to you at any time, command me, and use them as you wish."

MARION T. DAVIS, M.D.,

(University of Maryland School of Medicine.)

Atlanta, Ga., April, 15, 1905.

BRIEF CLINICAL REPORTS ON IMPOVERISHED BLOOD.

Probably the most frequent and important conditions which the average physician is called upon to treat, are of an impoverished blood supply. Blood impoverishment is a condition rather than a disease and may be met with in all walks of life and at any age. It is symptomatic as many disease, and cases are observed where it seems to be the chief clinical symptom where no well defined organic disease can be observed but where many indefinite complaints due to blood impoverishment are plainly in evidence. Whatever concomitant conditions exist with anemia and regardless of whatever special tratment may be demanded by plainly existing established organic trouble, it is, nevertheless, a fact, that the most complete and rapid cures are by restoring to the blood its normal elements. Consequently, the physician is justified in treating all cases of anemia with regard to the anemia itself, but at the same time, not over-looking the care of the other pathological conditions which may exist.

A large hospital experience has given me ample opportunity to study these blood conditions and compare the action of the many therapeutic agents employed in the treatment of blood impoverishment.

My efforts have been constantly directed toward finding the remedy which will have the most complete and rapid results in restoring the red blood corpuscles, thereby affording the surest and quickest relief from the weakness and general debility which always accompanies blood impoverishment.

In the beginning of my experiments I noted that those therapeutic elements containing a food produce and a stimulating vehicle have shown the most satisfactory and prompt results while those purely of a drug basis seemed to have a limited usefulness. The conclusion reached by my experiments extending over several years, leads me to unhesitatingly endorse Bovinine as being the best tonic, stimulant and food. Dr. John Griggs, Farmington, Conn.

THE USES OF ERGOAPIOL.

Ergoapiol (Smith) may be implicitly relied upon to promptly relieve the most intractable forms of amenorrhea, dysmenorrhea, menorrhagia, metrorrhagia, or, in fact, any disturbance of the menstrual function arising from a disordered condition of the organs of regeneration. It is an emmenagogue of incomparable excellence.

Preceding and succeeding the final cessation of ovulation and menstruation, physical and psychical disturbances of a more or less serious

character are frequently observed. Ergoapiol (Smith) because of its tonic effect upon the female generative system and its splendid antispasmodic influences, is of unsurpassed value in the treatment of the various disturbances incident to this period.

CARBUNCLES.

Creel has relied on ecthol given internally, in doses of a teaspoonful, in cases of carbuncles, flax seed poultices applied locally, emptying of pus, scrapping out of dead tissue and cleansing with peroxide of hydrogen after this a topic application of ecthol on absorbent cotton every four to eight hours. The average duration of this treatment in his cases was ten days. Journal of The American Medical Association.

A REVIEW OF THE REPORT OF THE ANEMIA COMMISSION UPON HOOKWRM DISEASE IN PORTO RICO.

The report of the Commission appointed by the United States Government, in February, 1904, for the Study and Treatment of Anaemia in Porto Rico, has been submitted to the governor of that island. This report covers over 200 pages, and is printed both in the Spanish and in the English language.

The Commission was composed of experts in their special field, and the amount of work accomplished by these gentlemen, and the exceedingly painstaking manner in which they attended to every detail of the subject, stamps this enquiry as one of the most scientific and thorough investigations ever undertaken in the cause of public health.

As early as 1899, Dr. Bailey K. Ashford, who later became a member of this Commission, discovered the parasite ankylostoma in the feces of anæmic patients who were then crowding the field hospitals of Ponce. This was the first positive evidence that the disease in Porto Rico known as anæmia, was not the ordinary form, but ankylostomiasis or uncinariasis, produced by the parasite sucking the blood, and so prevalent did this disease become during the ensuing years that fully ninety per cent of the population became affected.

When the Commission appointed by the Government of the United States began its investigation in Porto Rico, it established a hospital consisting of tent-wards, first at Bayamon, and later at Utuado, the most anæmic districts of the island. The object of the treatment was first to remove the parasite and then to cure the anæmia.

To kill the parasite, thymol, malefern, and betanaphthol were given but the preference was for thymol. First the patient received a purge of salts, and then on the following day he was made to fast until one o'clock

and then was given thymol in doses not exceeding four grammes; then another purge was given to remove the bodies of the parasite killed with the antiseptic. The purpose of the first purge was to clear the intestines of mucus, etc., so as to allow the thymol to act. The thymol and purge treatment was continued once a week until the feces showed no more uncinaria.

While thymol kills the parasite and the purges remove them from the intestines, also diminishing the amount of toxines in the system, these remedies only clear the field for a reconstructive process in the blood which is needful to restore the extremely anæmic patient to health.

Pepto-Mangan

Iron was given in the severe cases of anaemia. (Gudo) was the only proprietary remedy reported by the Commission, the other remedies used being pharmacopoeial preparations. That over eighteen pages of the report should be devoted to cases treated with PeptoMangan, proves the high regard in which the Commission held this preparation, and establishes the unrivaled clinical value of Pepto-Mangan (Gudo), in one of the severest forms of anæmia-that of uncinariasis, or miner's anæmia.

In reading the Report of the Commission, the unbiased character of the work stands out clearly, and yet the resultst obtained point so distinctly to the supremacy of Pepto-Mangan (Gudo), that even if numerous other records were not available, proving the therapeutic value of this remedy, this report alone would suffice to establish Pepto-Mangan at once as the foremost hæmatinic known. The eighteen cases in which the Commission used Pepto-Mangan (Gudo) in the treatment of uncinariasis, were selected on account of their extreme severity, and thus these cases represent the most crucial test to which any iron preparation can be subjected. The results obtained with this treatment were extremely gratifying. In nearly all of the cases we find such notes as these, “Excellent condition. Completely cured, etc.," while the difference between the low count of the red cells and the low percentage of hæmoglobin (some cases showing only 11 per cent.) at the beginning of treatment with PeptoMangan, and the nearly normal findings at the conclusion, affords convincing proof of the efficacy of the medication.

A noteworthy fact is that none of the patients showed any digestive disturbance after the administration of Pepto-Mangan, although the rem edy was used for many weeks in each case. When we remember the ex• tremely low state in which most of these patients were found on admission, and the fact that several suffered from gastro-intestinal symptoms incident to their disease, this detail is by no means to be underestimated. The observations of the Commission were made under Government control, and therefore the Report may be regarded as a supreme test, and the efficacy of Pepto-Mangan in one of the most severe forms of anæmia is proved beyond a doubt.