Molecular ToxicologyOxford University Press, 2006 - 589 sider The science of toxicology has progressed considerably since Molecular Toxicology was first published in 1997. New advances in biochemical and molecular biological experimental techniques have helped researchers understand the precise effects of toxins and foreign compounds on living things at the molecular, cellular, and organismal levels. Breakthrough research has recently been completed illuminating the human genome and the role of enzymes in toxic biochemical reaction mechanisms. Toxicology now covers drug metabolism and design, carcinogenesis, programmed cell death, and DNA repair, among other subjects. The second edition captures these and other advances, and broadens its scope to address the experimental science of toxicology. The first edition of Molecular Toxicology has become an indispensable resource for graduate students in molecular and biochemical toxicology courses, as well as academic researchers and industrial researchers in toxicology. Rigorously updated and revised, the new edition commands an unrivaled authority in the field of molecular toxicology. |
Indhold
I | xv |
II | 1 |
V | 2 |
VI | 7 |
VII | 10 |
VIII | 25 |
IX | 27 |
X | 46 |
CXLI | 333 |
CXLIV | 334 |
CXLV | 335 |
CXLVII | 337 |
CXLVIII | 340 |
CXLIX | 341 |
CL | 342 |
CLI | 346 |
XI | 47 |
XIII | 48 |
XIV | 49 |
XV | 51 |
XVI | 52 |
XVII | 54 |
XVIII | 56 |
XIX | 58 |
XX | 61 |
XXI | 63 |
XXIII | 66 |
XXIV | 73 |
XXV | 74 |
XXVI | 83 |
XXIX | 85 |
XXXI | 87 |
XXXII | 88 |
XXXV | 89 |
XXXVII | 90 |
XXXIX | 99 |
XL | 102 |
XLI | 105 |
XLII | 108 |
XLIII | 122 |
XLIV | 123 |
XLV | 124 |
XLVII | 125 |
XLIX | 127 |
L | 132 |
LI | 134 |
LII | 137 |
LIV | 138 |
LV | 139 |
LVII | 142 |
LVIII | 143 |
LIX | 145 |
LX | 155 |
LXII | 156 |
LXIII | 157 |
LXIV | 158 |
LXV | 159 |
LXVII | 160 |
LXVIII | 162 |
LXIX | 164 |
LXX | 165 |
LXXII | 166 |
LXXIII | 168 |
LXXV | 172 |
LXXVI | 174 |
LXXVII | 176 |
LXXVIII | 178 |
LXXIX | 191 |
LXXXI | 192 |
LXXXII | 199 |
LXXXIII | 203 |
LXXXIV | 204 |
LXXXVII | 208 |
LXXXVIII | 210 |
LXXXIX | 211 |
XCI | 212 |
XCII | 213 |
XCIII | 214 |
XCIV | 219 |
XCV | 220 |
XCVI | 227 |
XCVII | 228 |
XCVIII | 236 |
XCIX | 251 |
C | 252 |
CI | 264 |
CV | 265 |
CVI | 269 |
CVII | 270 |
CVIII | 271 |
CIX | 273 |
CX | 275 |
CXII | 277 |
CXIII | 279 |
CXIV | 282 |
CXV | 283 |
CXVI | 285 |
CXVII | 286 |
CXVIII | 287 |
CXIX | 289 |
CXX | 290 |
CXXI | 292 |
CXXII | 303 |
CXXVII | 305 |
CXXIX | 307 |
CXXXI | 308 |
CXXXII | 311 |
CXXXIII | 312 |
CXXXIV | 313 |
CXXXV | 315 |
CXXXVI | 316 |
CXXXVIII | 320 |
CXXXIX | 324 |
CXL | 326 |
CLII | 347 |
CLIII | 349 |
CLIV | 351 |
CLV | 353 |
CLVIII | 365 |
CLXI | 367 |
CLXII | 369 |
CLXIII | 371 |
CLXIV | 374 |
CLXV | 375 |
CLXVI | 376 |
CLXVII | 377 |
CLXVIII | 380 |
CLXIX | 381 |
CLXX | 382 |
CLXXI | 383 |
CLXXII | 386 |
CLXXIII | 387 |
CLXXIV | 388 |
CLXXV | 402 |
CLXXVI | 403 |
CLXXVII | 406 |
CLXXVIII | 407 |
CLXXIX | 410 |
CLXXX | 411 |
CLXXXI | 414 |
CLXXXIII | 418 |
CLXXXIV | 419 |
CLXXXV | 426 |
CLXXXVI | 427 |
CLXXXVII | 428 |
CLXXXVIII | 429 |
CXC | 430 |
CXCI | 431 |
CXCII | 432 |
CXCIII | 434 |
CXCIV | 436 |
CXCV | 439 |
CXCVI | 448 |
CXCVII | 450 |
CXCVIII | 451 |
CXCIX | 452 |
CCI | 453 |
CCIII | 456 |
CCV | 457 |
CCVI | 458 |
CCVII | 462 |
CCVIII | 467 |
CCIX | 468 |
CCX | 469 |
CCXI | 470 |
CCXIII | 471 |
CCXIV | 472 |
CCXV | 473 |
CCXVI | 476 |
CCXVII | 477 |
CCXIX | 478 |
CCXX | 484 |
CCXXII | 485 |
CCXXIII | 487 |
CCXXIV | 488 |
CCXXV | 495 |
CCXXVI | 496 |
CCXXVII | 500 |
CCXXVIII | 509 |
CCXXXI | 513 |
CCXXXII | 514 |
CCXXXIII | 515 |
CCXXXV | 516 |
CCXXXVI | 517 |
CCXXXVII | 518 |
CCXXXVIII | 521 |
CCXXXIX | 522 |
CCXL | 524 |
CCXLI | 531 |
CCXLIII | 532 |
CCXLIV | 534 |
CCXLVI | 535 |
CCXLVII | 540 |
CCXLVIII | 541 |
CCL | 542 |
CCLI | 544 |
CCLII | 546 |
CCLIII | 549 |
CCLIV | 550 |
CCLV | 551 |
CCLVII | 552 |
CCLVIII | 554 |
CCLIX | 562 |
CCLX | 563 |
CCLXI | 564 |
CCLXIII | 565 |
CCLXIV | 566 |
CCLXVI | 568 |
CCLXVII | 570 |
CCLXIX | 571 |
Andre udgaver - Se alle
Molecular Toxicology P. David Josephy,Bengt Mannervik,Paul R. Ortiz de Montellano Ingen forhåndsvisning - 1997 |
Almindelige termer og sætninger
Acad acetaminophen acetyl activity allele amino acid analysis apoptosis aromatic amines assay atom base benzo[a]pyrene binding Biochem Biochemistry Biol biological Biophys bond cancer carbon Carcinogenesis carcinogens catalyzed cells cellular chapter Chem chemical chromosome codon coli compounds covalent cysteine cytochrome b5 cytochrome P450 damage detection dihydrodiol DNA adducts DNA repair drug electron electrophilic encoding enzyme epoxide figure appears formation full-color version function gene genetic genome glucuronide glutathione transferase heme hemoglobin hepatic human hydrocarbons hydrogen hydroxylation inactivation induced interactions ligand lipid liver mammalian Mannervik mechanism membrane metabolism metabolites mice microsomal molecular molecules mouse mutagenesis mutagens mutations Natl nuclear receptor nucleophilic oxidative stress oxygen P450 enzymes PAHs pathway peroxidase peroxide Pharmacol polymorphism Proc protein radical reaction reactive receptor redox reduced reductase residues role sequence specific strand structure studies substrate sulfate sulfotransferase superoxide dismutase target tissue toxicity Toxicol tumor vitro xenobiotic

