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REPRINTS, ETC., RECEIVED.

The Gross Medical College Bulletin, 1895. University of Tennessee. Medical Department. 1895.

1895 Wholesale Catalogue of the J. Ellwood Lee Co., Conchohocken, Pa.

Treatise on Cod Liver Oil with Peptonate of Iron. Frederick Stearns & Co.

Transactions of the Colorado State Medical Society. Twenty-fourth Annual Convention. Denver, 1894.

A. C. McClurg & Co. will shortly publish "The Eye in its Relation to Health," by Chalmer Prentice, M. D.

List of Surgical Splints exhibited at the Columbian Exposition, Chicago, 1893. Edward A. Tracy, M. D., Boston.

By

The Therapeutic Application of Peroxide of Hydrogen (Medicinal), Glycozone and Hydrozone. By Charles Marchand, Chemist. 1895.

Vegetable Nucleo-Toxine in the Treatment of Cancer. By J. E. Chambers, M. D., St. Louis. Reprint from the St. Louis Courier of Medicine.

A Study of Thirty-Nine Cases of Strangulated Hernia. By William Burton DeGarmo, M. D., of New York. Reprint from the Annals of Surgery.

Die Prophylaxis der Tuberculose and ihre Resultate. Von Prof. Dr. G. Cornet (BerlinReichenhall) Reprint from the Berliner Klinische Wochenschrift.

A New Method of Examination and Treatment of Diseases of the Rectum and Sigmoid Flexure. By Howard A. Kelly, M. D., of Baltimore. Reprint from the Annals of Surgery.

The Rio Chemical Company's Map of the World is complete and corrected up to date. Physicians may receive a copy free by mailing their address to the Rio Chemical Co., St. Louis, Mo.

Some Observations Concerning a New Test for the Detection and Quantitative Estimation of Free Hydrochloric Acid in the Gastric Juice. By Julius Friedenwald, A. B., M. D., Baltimore. Reprint from the Medical Record.

CURRENT EDITORIAL COMMENT.

TESTIMONIALS.

Atlantic Medical Weekly. WHILE we have not at present positive proof, we are firmly convinced that when a physician lends his name to a laudatory advertisement of a remedy, proprietary or not, he receives a compensation of some sort, and when a clergyman allows to be published over his signature and under his portrait a letter of recommendation for some nostrum, he either receives pay for it or his desire for notoriety overbalances his judgment. In either case the act is one to be condemned.

CHEAPER MEDICAL BOOKS. Journal of Medicine and Science. IT is and has been for years a constant complaint that the price of medical books is exorbitantly high. And more than that, that 'the difference even in the bindings is exorbitant, considering the actual cost of the difference in the material with which the different editions are bound, and the extreme cheapness of binding books in any material at all. To demand an extra dollar on the difference between a cloth and the next extra binding is to put half of that price into the bookmaker's hands.

HIGHER MEDICAL EDUCATION.

Mathew's Medical Quarterly.

IT was once said that, whenever a man had a son who by the want of intellectual endowment or the absence of the proper qualifications was unfitted for a business life, the father immediately proceeded to make a doctor of him. If one will take the time to notice the class of men that have been annually graduated from even the best colleges in the United States, it will not strain the imagination much to see that this statement has a grain of truth in it. Fortunately for our pride, our self-respect and for the good of the people at large, that day has passed. It was glad tidings to the medical profession of this Union to hear the echoes from the meeting of the American Medical Association, at Baltimore, demanding a four-year course in medical education before receiving recognition in that great body as a member. The interest was made more manifest when it was announced that the American Medical College Association would require a four years' attendance before graduation.

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PUBLISHERS' DEPARTMENT.

All letters containing business communications, or referring to the publication, subscription, or advertising department of this Journal, should be addressed as undersigned.

The safest mode of remittance is by bank check or postal money order, drawn to the order of the Maryland Medical Journal; or by Registered letter. The receipt of all money is immediately acknowledged.

Advertisements from reputable firms are respectfully solicited. Advertisements also received from all the leading advertising agents. Copy, to ensure insertion the same week, should be received at this office not later than Monday.

Physicians when communicating with advertisers concerning their articles will confer a favor by mentioning this Journal.

Address:

MARYLAND MEDICAL JOURNAL,

209 Park Avenue, Baltimore, Md.

NOTES.

GONORRHEA in married people can only be successfully treated when both husband and wife undergo treatment at the same time and during treatment cease all sexual relations.

IN obstinate cases of menorrhagia excellent results may often be obtained by the administration of five minims of oil of erigeron every three or four hours. It is best given in capsule or on a piece of lump sugar.

THE presence in the sick-room of flowers with delicate fragrance is generally beneficial. Certain colors are said to act favorably upon the nervous system. Red blossoms are stimulating, while delicate blue flowers are soothing.

IT is advisable, in the administration of drugs that are to be used for some length of time, to discontinue their use at intervals, or the system becoming accustomed to their influence, will refuse to respond to their action. Especially is this the case with the bromides and iodides in the treatment of chronic conditions.

SALICYLATE of soda is recommended as little less than a specific in acute tonsillitis. It should be given as early in the attack as possible, and in sufficient doses to cause ringing in the ears. Fifteen grains every three hours will usually cause this effect, when the dose may be diminished to ten, and then to five grains at the same intervals. It should be continued a day or two after disappearance of the fever.

PHARMACEUTICAL.

FOR the treatment of chronic nasal catarrh, Borine, on account of the stimulating and cleansing property it possesses, reduces the congestion, removes the scaly deposits, and stimulates and tones the mucous membrane to a healthy condition. In fetid rhinitis and ozena Borine destroys the bad odor and diminishes the purulent discharges. It reduces the droppings of mucous from the nose to the throat in naso-pharyngeal catarrh.

THE steadily increasing use of Bromidia by the profession in all parts of the world de. monstrates its great value as a hypnotic. If human testimony is worth anything at all, then Bromidia must unquestionably be the best and safest of all sleep producers. Dr. Federico Tommasi, of Maggranico, Italy, on July 24, 1893, writes: "Although as a rule I do not approve of specialties, still when I find an ideal one, both as regards therapeutic combination and pharmaceutical preparation, easily administered, prompt and certain in action, I value it. Bromidia fulfills all these conditions. I have obtained especially gratifying results by its use in two cases- one, heart disease, the other, acute lumbago. In both cases it promptly relieved the pain, produced tranquil sleep, with no disagreeable after-effects."-Memphis Medical Monthly, June, 1895.

FRANK MCDONALD, M. D., College Physicians and Surgeons, Baltimore, Md., 1883, Supreme Medical Director W. S. of I. O. U. A., Medical Examiner Equitable Life of N..Y., Secretary Pittsburgh Obstetrical Society, etc., says: "Your Succus Alterans gives me perfect results. I presribe it almost daily, and have never failed to obtain the effect sought. I regard it a specific for syphilis in all stages. Imitations which I have been induced to try occasionally have always failed. Such failures have only served to confirm my confidence in the genuine Succus Alterans. I can pay no greater tribute to an article so worthy and so meritorious than to say it is the very best and safest alterative known to the profession."

LISTERINE is a very convenient and agreeable means of securing topical antiseptic medication. It may be applied in full strength or diluted, to superficial cuts, bruises, or abrasions, as a toilet antiseptic wash after shaving, etc., as well as for the treatment of vari

ous specific diseases of the skin. Listerine, ALTA PHARMACAL CO.; Gents:-Your rep

with water, glycerine, or other medicaments, is variously employed in all forms of eczema, different conditions suggesting degree of dilution; after the application of Listerine the eruption may be dusted with starch powder, or starch powder with the oxide of zinc, relieving the distressing itching and irritation. The following has also given special satisfaction :

B.-Liquor Picis Alkalinus.
Listerine.

Sig. Apply as a lotion.

q. s. ft.

3ij ij M.

J. P. PARKER, PH. G., M. D., of St. Louis, Mo. (Annals of Ophthalmology and Otology, of St. Louis, Missouri, April, 1895) says: I have used peroxide of hydrogen quite extensively for cleansing discharging ears, the nasal and accessory cavities, and have tried all the brands of the preparation in the market, and once thought one manufacturer's make as good as that of another, and bought the cheapest as a matter of economy, but recent experience has taught me that the difference in quality is greater than the difference in price. After an unpleasant experience with a solution of peroxide of hydrogen which severely injured the mucous membrane, I bought and examined, chemically, a bottle of each preparation of H2 O2 in the market, and was surprised to find so much difference. Some are useless, and others worse than useless because they contain too little available oxygen and too much free acids (phosphoric, sulphuric, hydrochloric). I now order Marchand's (medicinal) exclusively because I find it contains the desired quantity of available oxygen and not enough free acid to be objectionable, and its keeping properties are all that could be desired. By inquiry I learn that Marchand's is the preparation that is used by almost all surgeons, and it is considered by them the standard.— My personal experience with peroxide of hydrogen confirms entirely the statement of Dr. J. P. Parker, I have used exclusively Marchand's brand until lately, when I experimented with hydrozone. Then I gave up entirely the use of peroxide of hydrogen and use hydrozone on account of its strength, which cannot be compared with any other brand, even Marchand's. I must say that the results which I obtained with hydrozone are most gratifying.-Ed. (Abstract, Times and Register, June 8, 1895.)

resentative called to see me six or seven weeks ago and left a dozen bottles of your preparation, Melachol, requesting that I would use it when I could. I kept accurate notes and made practical observation in a number of cases and I believe that Melachol is scarcely · less than magical in its effects upon all ill nature. It certainly holds the cholesterin in a liquid form and prevents the formation of gallstones and the clogging of the gall duct, nor does it produce a less happy effect upon the secretions of any gland in the body. Even the mucous glands respond to its action and old and doubly chronic cases of uterine diseases accompanied by acrid and offensive discharges rapidly improve under its benign stimulation, and irregular and painful menstruation, if not through organic displacement, is wonderfully improved by its administraion just prior and during the period of menstruation. I have had excellent results in its use in disorders of the liver and kidneys. It has never failed to respond in increasing the secretions of these organs and greatly assisting nature where aggravated disturbances have existed for years. My most noticeable result was its action in a case of chronic hysteria in a woman, age 35, of careless habits. Examination showed that a hypertrophied condition of the uterus existed, together with congestion of the ovaries, with continuous pain, to subdue which morphia had been used and the habit contracted. I discontinued all other remedies except morphia and gave Melachol in drachm doses three times a day and full laxative dose (tablespoonful) twice a week continued for a month. At this time patient is much improved. Hysteria almost gone, organs in nearly normal condition, and by reducing the dose of morphia without the patient's knowledge until none was taken, she was surprised to know it, but found she could do without it altogether and as the cause had been removed, she did not resume the habit nor did she crave the drug. The patient was discharged with instructions to return if improvement was not permanent. I have been able to fully satisfy my mind of its efficacy and medicinal qualities, and it has won my admiration fully, and to my brothers in the profession I commend it without reserve. Very truly, R. M. Kerley, M. D., Superintendent Health Department, City of St. Louis, Female Hospital.

MEDICAL JOURNAL

A Weekly Journal of Medicine and Surgery.

VOL. XXXIII.-No. 14.

BALTIMORE, JULY 20, 1895.

WHOLE NO. 747

ORIGINAL ARTICLES.

VAGINAL CYSTS.

READ AT THe 787th RegULAR MEETING OF THE MEDICAL AND SURGICAL SOCIETY OF Baltimore, held at Carroll Hall, MAY 23, 1895.

By William S. Gardner, M. D.,

Associate Professor of Gynecology College of Physicians and Surgeons.

CYSTS are found both in the anterior and posterior vaginal walls, the greater number being found in the anterior wall. They vary in size from that of a pea to that of the fetal head at term. Courty states that they are of frequent occurrence in prostitutes, and Tillaux and Thallinger consider them as hydromata or accidental serous sacs. Scanzoni and Rokitansky always found that the origin was not in the vaginal wall proper but in the cellular tissues outside of the vagina. The mucous membrane over the cyst, as a rule, maintains its normal appearance, but it sometimes becomes much stretched or adherent and losing its characteristic rugae, becomes smooth and glossy. The growth in all cases is slow and cysts have been kept under observation from a few months to as much as twenty-two years.

Efforts have been made to determine the origin of vaginal cysts by the examination of their contents, but no definite results were obtained, it being found that cysts having evidently the same origin had great variations in their contents. Their origin has also been sought for in the histological structure of their sacs but the changes produced by the growth of the cyst and the internal pressure so modify the epithelial linings that it is difficult to decide from just what form they have developed. Ruge and Kalten

bach have found two distinct varieties of epithelium present in the same cyst.

Von Preuschen's investigations led him to state that many vaginal cysts are simple retention cysts such as are found in other parts of the body; but this view has been combatted by many observers, who deny the possibility of retention cysts by denying the presence of glands in the vaginal walls. Nevertheless, it is highly probable that von Preuschen was correct in his conclusions.

Klebs argued that vaginal cysts are simply dilated lymph channels. Schulte quotes a case that he believes arose from a dilated lymph vessel under the influence of persistent inflammatory irritation.

Freund suggested that these cysts might be due to an accumulation of fluid in a duct of Müller which during development had failed to unite with the one on the opposite side.

Froment thought that cysts were formed by the adhesion of the crests of the rugae leaving a cavity lined with normal vaginal mucous membrane which gradually becomes distended with the secretions from the membrane.

In rare instances dermoid cysts and hydatids have been found in the vagina, and traumatic hematomata have sometimes been classed as vaginal cysts.

G. Veit, in 1867, first suggested that

some vaginal cysts might have their origin in Gärtner's ducts, and it is to this form of vaginal cyst that I wish to call special attention. The fact that these ducts are persistent in the cow, sow and many other animals has been long known. Their presence and the degree of their patency in woman has been a much discussed subject. It would be of little advantage to reiterate the names of all those who have discussed the pros and cons of the existence of Gärtner's ducts in the adult, and so far as possible, I will relate facts rather than opinions.

In 1887, Dr. G. W. Johnston of Washington reported a case of which the following is a brief outline:

Mary M., aged 30, colored; she complained of pelvic pain, leucorrhea and painful coition; during the past two months difficult urination with attacks of retention. Physical examination revealed laceration of the perineum, laceration of the cervix, subinvolution, vaginitis and on the right half of the anterior vaginal wall, lying one below the other in a straight line, four elevations that proved to be cysts. Three cysts were spherical, the fourth elongated and having the long axis parallel with the axis of the body. They decreased in size from above downward. All four cysts were tapped with a hypodermic needle and the fluid drawn off. The smallest one never refilled. One suppurated after the puncture and was cured by free incision and packing with iodoform gauze; it gradually filled with granulations and healed over. One was simply split open. The largest one was treated by cutting away as much of the cyst wall as projected into the vagina, and then the edges of the remaining portion were stitched to the vaginal mucous membrane. A microscopical examination of part of the cyst wall removed showed it to consist of connective tissue and unstriped muscular fiber and lined with epithelium. Johnston believes that the cysts in this case originated in a dilatation of the vaginal portion of the right Gärtner's canal.

At the April meeting of the London Obstetrical Society, Dr. Armand Routh detailed three cases of associated par

ovarian and vaginal cysts formed from a distended Gärtner's duct, and also of two analogous cases of patency of the whole length of the duct with an anterior opening allowing free drainage and thus preventing distention. By evidence from these cases he thinks to establish or at least to render plausible the following propositions :

1. That Gärtner's duct can be traced in some cases in the adult female from the parovarium to the vestibulum vulvae, ending just beneath and slightly to one side of the urethral orifice.

2. Homology tends to show that Max Schüller's glands are diverticula of Gärtner's ducts, just as the vesiculae seminales are diverticula of the vasa deferentia. Some evidence is given that Skene's ducts are not necessarily identical with the anterior termination of Gärtner's ducts (as most of those who have traced Gärtner's ducts to the vestibule have thought) but that Skene's ducts lead directly and solely from Max Schüller's glands, Gärtner's ducts being continued to the vestibule, behind, but parallel to Skene's ducts.

3. That Gärtner's duct, if patent, may become distended at any part of its course, constituting a variety of parovarian cyst if the distention be in the broad ligament portion, and a vaginal cyst if the distention be in the vaginal portion. The cases described are instances of the association of both of these cysts, owing to simultaneous patency of distention of both portions of the duct.

4. Attention is drawn to these cases as affording explanations of some obscure cases of profuse watery discharge from the vagina, not coming from the uterus or bladder.

5. The question of treatment is also approached, and the opinion is expressed that where the whole duct is distended the vaginal part of the cyst may be laid open as far as the base of the broad ligamènt, and the broad ligament portion encouraged to contract and close up.

CASE I.-Miss C. C., aged 25, complained of a profuse yellow, watery discharge which was occasionally offensive. Walking caused great pain down the right leg and in the right side. The

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