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resisted the usual methods, during upwards of two months. A grain and a half of the muriat was given in half an ounce of rectified spirit of wine, at bed time. A dose of Glauber's salt was given on the morning of the second following day, and the draught was to be repeated in a day or two more, and to be followed by the use of the salts. A copious salivation was immediately excited by the first draught, and more than a quart was thus evacuated. Next day, the symptoms of the gonorrhoea were much relieved. After three more repetitions of the draughts, Mr. Addington deented the patient so well as to require no farther medicine. He, however, chose to take two additional draughts, and then remained perfectly well. - In twelve other cases, which are particularly stated, a remarkably speedy cure was effected by this method; excepting that the dose, in some instances, was lessened to a grain at a time. (See p. 70.)

A Case of Mortification of the Toes and Foot. By Mr. Kentish, Surgeon, Newcastle-upon-Tyne.

In this case, amputation of the limb was performed; and it was found that the femoral artery was beginning to ossify. The stump, some time after amputation, took a tendency to inflammation, and seemed likely to run into a gangrenous state. Mr. K., conceiving that his patient, (who was about o years of age, and had lived well,) had created the disposi tion in the arteries to ossification, by the use of stimulants; and having found that bark, wine, and opium, had not suc ceeded in stopping the progress of the mortification in the ampuated part, determined to try the effect of blood-letting. Al mest immediate relief was experienced. Twelve leeches were afterward applied to the stump, where it was inflamed; a pur gative was given on the following day; and this process was repeated in about a week. Appearances continuing to be favourable, eight ounces of blood were taken away weekly, during six weeks, and purgatives interposed occasionally. The patient perfectly recovered.

This, Mr. Kentish remarks, was a case similar to those in which Mr. Pott recommends opium; a practice which he (Mr. K.) has never known to succeed. He supposes the ossification of the arteries to have been the cause of the disease; and he thinks that the disposition to ossification was produced by the daily use of fermented liquors and animal food. Our readers will decide for themselves, on the probability of these opinions: but they certainly led Mr. K. to a practice which was amply justified by the event.

Observations on Garbuncle. By Mr. Yonge, Surgeon, Shif hal, Shropshire.

This

This is an instructive and valuable account of a painful and dangerous disease. The repeated application of cold water afforded the patient more relief than any other remedy.

This case leads Dr. Beddoes into reflections on the use of cold applications in different discases. He gives an instance, furnished by Dr. Hamilton of Ipswich, of a catarrh, attended with inflammatory symptoms, which was cured by the exposure of the patient to the night-air, during a hard frost. To this fact, Dr. B. has added several from the writings of Floyer and Baynard, to prove the good effects resulting from cold air, and cold bathing, in febrile diseases.

Miscellaneous Reports and Observations concerning the Respiration of Gases and Vapours.

Mr. Creaser, a surgeon in Bath, gives an account of a case of chlorosis, accompanied with an herpetic affection of the face, and effusions of blood into the cellular membrane; from which, considerable hemorrhages frequently took place. The usual methods of practice did not succeed, and Mr. Creaser resolved to try the effects of oxygen gas. After having used it for a month, by which time three quarts of oxygen were given three times in a day, appearances of recovery began to be evident. The oxygch was continued for three months; increased the strength and fulness of the arterial system, with out augmenting the hemorrhage; and the patient gradually recovered her health. Dr. Crouther of Wakefield relates a case of pulmonary abscess, cured by the exhibition of hydro-carbonat-gas. The facts stated in this instance, however, are not at all decisive: for the patient, besides mucilaginous medicines and opiates, used elixir of vitriol to check the sweatings; and, during the greater part of the course, he took a powder twice in a day, containing eight grains of myrrh, a grain and a half of vitriolated iron, and ten grains of colombo

root.

The case of a woman, mentioned also by Dr. Crouther, in proof of the efficacy of ethereal vapour in consumption, is unsatisfactory, from similar circumstances. She suckled twins, at the commencement of the disease; and we must certainly ascribe her recovery, in part, to her being injoined to wean them, as well as to the allowance of more nutritive diet.

In the case of Miss Norton, stated by her apothecary, there seemed to be advantage derived in phthisis, from the exhibition of hydrogen gas: but it does not appear whether she ultimately recovered.

Summary of the late Dr. Geach's Practice in low Fever. Mr. S. Hammick, Jun.

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The peculiarity of Dr. Geach's practice consisted in giving large doses of calomel, combined with antimonials, at short intervals. We are informed that eight grains of calomel, and four of pulvis antimonialis, were given in every six hours when the symptoms were slight: but, in urgent cases, that quantity was given every three, or even in every two hours. We are farther told that not only was no ptyelism excited by this profuse exhibition of calomel, but that the patient became costive during the process! This dose, it is added, has been continued to some patients, every three hours, for eighteen or twenty days.'

This method, Mr. Hammick declares, was pursued by Dr. Geach not only in hospital practice, but in a most extensive range of private business. These assertions we certainly do not mean to dispute: but we are greatly surprised to find mercury employed in such enormous doses, without any theory, or assignable principle, by gentlemen who, on the subject of the venereal disease, have declared open war against this remedy.

Extracts of Letters, from Mr. Cooke, Apothecary, Gloucester, and other Practitioners, respecting the Cow pox.

Mr. Cooke inoculated Mrs. Carter, aged 5c, with variolous matter, after she had assured him that she had undergone the cow-pox at eighteen years of age. At that time, she lived in a dairy-farm, in Longney; the cows were affected with chopped and sore teats; all the servants who stripped these cows, had inflammation and boils upon their hands. She was so ill with fever, and these boils, that she could not work for a week; her hands and arms were dreadfully swelled, and she kept her bed for two days. In this state, she applied to Mr. Cooke, who then was in practice at Frampton, in this county; he told her, "she had the cow-pox very bad, and that it was a disease the nearest to the small-pox that could be."-This patient had a large crop of small-pox, in consequence of the inoculation.

Another instance is mentioned by Mr. Cooke, but only from report, of a farmer, who, many years after having had the cow-pox, caught the small-pox by infection, in coming to Gloucester market, and died of it.

Mr. Thornton, surgeon at Stroud, took some cow-pox matter from a man infected by the cows which he milked, and who had never had the small-pox. With this matter he inoculated a family, consisting of the father and four children, They all had a severe local affection of the inoculated part, but without general fever, or eruption. On inoculating them afterward, for the small-pox, all the children took the disease; the father did not receive it.

Mr.

Mr. Thornton mentions other instances of the same kind, from information. (See a subsequent article, p. 70.)

Answers to Mr. (now Dr.) Adams's Queries, concerning the Sivens. [By Dr. Paterson of Air).

It appears from this paper, that the Sivens (or Sibbens as some authors spell it) affects the system in a manner dissi milar to the venereal disease, though it is cured by slight courses of mercury; and best, in Dr. Paterson's opinion, by corrosive sublimate. It chiefly attacks the throat and surface, Case by Mr, G. Vise, Stilton.

An instance of a dropsy, cured by long-continued vomiting, which seemed to be excited by a fall on the belly.

On the Use of Nitrous Acid in restraining Sickness. By the Editor.

Dr. Beddoes has found small doses of the nitrous acid successful in removing nausea, in dispeptic cases.

On Nitrous Acid in Dropsy, by Dr. Luke, Physician at Fal

mouth.

A dropsy was cured by the exhibition of nitrous acid, after a mercurial course; though the patient had been previously tapped, without experiencing relief in his anasarcous symptoms, The use of the acid is said to have supported the soreness of the mouth and spitting, originally excited by the mercury.

Note on ditto, from Mr. Scott, of Bombay.

Mr. Scott informs us that the nitric acid, employed as a bath, is absorbed very plentifully by the skin, and produces the same effects which result from its internal use. He says that it causes salivation, in this manner, sometimes after the patient has been bathed daily for a week, sometimes in a shorter period.

He recommends trials of this acid in dropsical cases, and adds, if your ascites arises from the same causes with that of this country, I promise you great success.'

An Account of several Veins of Strontian or Strontites, found in the Neighbourhood of Bristol; with an Analysis of the different Varieties. By William Clayfield.

Specimens of this substance, which had been found near Bristol, had generally passed for varieties of the sulphat of barytes. Mr. Clayfield has ascertained their real nature by experiment, and has given a particular account of the situa tion and appearances of the veins, and of the varieties which they contain.

Dr. Beddoes adds, in a note, that strontian has been dis covered in some parts of Cumberland. The paper is short, and does not admit of farther detail. F 3

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On the Whitening of Bones. By Mr. Smith.

The process here recommended is the exposure of bones to the action of the oxygenated muriatic acid gas. It renders them beautifully white.

Letter from Mr., Surgeon of Hospital, on Gonorrhea,

This paper will operate as a useful warning to those who might have been induced to give the large doses of muriat of quicksilver, recommended by Mr. Addington, in gonorrhoea. The author of this relation tried the practice, on the faith of Mr. A.'s cases. In one instance, he found very alarming symptoms produced by it; and, in another, great inconvenience, without effecting a cure of the gonorrhoea in either, We suppose that Mr. Addington's paper must have been printed before the present communication was received. As it is,

"Our bane and antidote are both before us."
Letter on ditto, from Mr. Addington.

Mr. Addington here imputes the noxious effects of the muriat of quicksilver, in the last-mentioned cases, to the omission of the doses of Glauber's salt inculcated by him; to the short intervals of the doses of the muriat; and to the great number of doses exhibited.

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Note by the Editor on the Use of Mercury in Febrile Diseases. Contains several authorities for the employment of mercury in fevers.

Note from Dr. Jenner, respecting the preceding Facts on Corv-pox, Dr. J. here requests the public to suspend their opinion on Mr. Cooke's and Mr. Thornton's letters, till the appearance of his supplemental pamphlet; which we have noticed in our last Review.

Answer by Mr. Jacobs, Attorney at Law, Bristol, to Queries proposed by the Editor respecting the Cow-pox.

Mr. Jacobs had the cow-pox early in life, and, about ten years afterward, took the small-pox by inoculation. His details of the former disease seem to be clear and accurate.

A Letter to Dr. Beddoes, containing Observations on the Usa of Digitalis in Pulmonary Consumption, with two Cases in which it proved permanently successful. By Nathan Drake, M. D.

Dr. Drake exbibited the tincture of digitalis, in two cases of phthisis, in such doses as to reduce the pulse in one case from 120 to 40; and in another, from 120 to 50 in a minute. Both patients were cured, after well-marked symptoms of phthisis had taken place. Dr. Drake supposes, with great probability, that the beneficial effects of digitalis, in this disease, depend on its power of retarding circulation. We

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