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colored; I also noticed some undigested particles of food. The stools appeared frothy, owing to the great force with which they were expelled. The sensation of goneness and prostration accompanied each passage, also the head symptoms, especially the piercing pain in right temple. About 8 P.M., had another characteristic stool. When urinating could hardly tell when urine was passing. There seemed to be a weakness of the sphincter of the neck of the bladder. The urine at times would feel hot, and leave a tingling sensation in urethra.

August 17th. Had a very large stool, very thin and yellowish, and the last part contained undigested food. The sphincter ani muscles feel greatly relaxed. Anus feels open after passage of stool. The head symptoms and the feeling of goneness and prostration all very prominent. Had another stool in the evening, it was very large or copious, at first very thin, but towards the end it was mixed with fæces in small lumps.

August 18th. Had a very copious stool in the morning. It seems as though the gate was wide open, and everything in me had passed out. Stool was very thin and brownish. About an hour after had another stool of the same character. The pain in right temple after this stool was very prominent, also the great prostration of whole system. Some grumbling and disagreeable feeling in bowels. Inclination as if stool would frequently pass. These stools are expelled with force.

Second test with 0 of the fresh roots.—August 29th, 1877. Took ounce just before retiring. Slept very well.

August 30th. Took ounce of same about 7.15 A.M. Bowels moved at regular time; first part of stool natural and latter thin. Had some tenesmus after stool. Weak feeling in abdomen and some rumbling. Passed much flatus. Flashes of heat followed by quite profuse perspiration. Spittle quite thick and tenacious. Expectorate considerable amount of white gelatinous mucus. Pulse 68. At 1.40 P.M. took ounce of same. An aching pain in sacrum, and at times sharp and sticking, appearing occasionally in hip, knee, and ankle joints. Darting pains in different parts of bowels; feels as if wind or flatus was expanding the intestines. Pain in right temple, followed by confused and dull aching pain in head. Vertigo at times, and aggravated by ascending. Rumbling in bowels.

At 5.15 P.M. took ounce of same. Soon after eating the lower part of abdomen felt distended. Perspiration quite profuse. After urinating felt a dull pain in neck of bladder, also in urethra; the pain in neck of bladder gave the sensation that the sphincters were trying to close but could not, thus showing an inactivity of these muscles. Had attacks of much nausea, making me feel deathly sick. Could not vomit. Much vertigo.

August 31st. Had quite a severe headache when waking. Restless during the night. At 7.50 A.M. took ounce of same. A very large stool about 9 A.M., thin and brownish. Some flatus. No pain. Sphincter ani feels relaxed and there is loss of power. Aching pain in umbilical region after stool, also a feeling of great goneness, accompanied by pain, first in right temple, then extending through whole head, making it feel much confused. Vertigo. Pain again in knee joints, especially left. At 6 P.M. took ounce. Some nausea. Head symptoms continue as before, followed by spells of marked vertigo.

September 1st. Stool in morning large and of a brownish hue, thin and watery. Feeling of goneness and grumbling aching pain in umbilical

APOCYNUM CANNABINUM. DR. CHAPIN'S PULSE.

Л.

Nos. 1 and 2.-Dr. Chapin, in health, two tracings.

No. 3.-September 16th.

Nos. 4 and 5.-September 28th.

Nos. 6-9.-Four successive tracings, September 29th, at 6 P.M.

Nos. 10 and 11.-September 30th, 6 P.M.

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