Neurobiology of Disease

Aimed at the basic scientist or clinician scientist teaching a course or conducting research in the basic science underlying the major neurological diseases, this book provides cutting-edge research on the fundamental mechanisms, including molecular, responsible for these diseases. The major categories of neurological disease have been covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book includes approximately 20 topics, each divided into several individual chapters that are exemplary of the topical area. The topics include the major categories of disease, including metabolic, neurodegenerative, genetic, neuroimmunological, cerebrovascular, paroxysmal, neoplastic, infectious, and developmental. There are also sections on motor neuron diseases, peripheral neuropathies, myopathies, autonomic disorders, pain, sleep disorders, substance abuse, neurological disturbances associated with medical diseases, and techniques for imaging the nervous system. The chapters are written by acknowledged experts in their fields, and each contains appropriate tables, illustrations and references. Provides cutting edge information about fundamental mechanisms underlying neurological diseases Amply supplied with tables, illustrations and references Includes supporting clinical information putting the mechanisms of disease into perspective