DEAR DOCTOR For Acute and Chronic And Kindred Complaints, prescribe the "old reliable " Griffith's Compound Mixture of which contains Guaiac, Stillingia, Prickly Ash, Turkey FOR FURTHER PROOF, we will, upon request, send you by Express a regular $1.25 size bottle as a sample for trial, providing you will enclose 30c. for the Prepayment of Express Charges. GRIFFITH & CO. Prescription Pharmacists 67 Third Ave., Cor. 11th St., New York Advertising of this preparation is confined strictly to LANIKOL is like Building a House ::: The finished structure must necessarily reflect the material of which it is composed No firm can establish a reputation on a high-class specialty unless it employs first-class goods. Our aim has always been to meet the ever-increasing demand for a first-class ointment that can be used with good results in the majority of Skin Diseases, etc., etc. Our large and increasing business has been built up by supplying such a product, and those Doctors who are willing to encour ge our efforts are invited to write for free samples and constituents of our product to 1-ez. Jars, $3.50 per dozen. 4 oz. Jars. $9.50 per dozen. The LANIKOL CHEMICAL CO., Milwaukee, Wis. 1-lb. Jars, $2.50 each. STOCKED BY JOBBERS. oxygen is then carried in the blood plasma as well as in the red corpuscles, to the various tissues of the body. The oxygen is finally delivered to the tissues by the plasma, and not by the corpuscles, which are too large to enter the smallest passages. Thus the red corpuscles become merely carts or sponges, to carry the oxygen near where wanted, the final step in metabolism being made by the plasma, which is enabled to do this by the supra-renal secretion which it contains. This, if true, is a physiological fact that entirely changes our establisht views. Pathologically it is of no less importance, on account of its relation to fever, the various toxins and their destruction, etc. It is claimed that the other ductless glands, as the thy roid, spleen, etc., yield "internal secretions," carried by the blood leaving them thru their veins, and that these secretions are both physiologically and patholog ically important. Dr. Sajous also assigns functions of the greatest importance to the anterior and posterior pituitary bodies. If the claims of this book shall be proven and accepted, many of the most important of our accepted principles and theories in physiology and pathoolgy will be revolutionized. The American Year-Book of Medicin and Surgery for 1903. A yearly Digest of Scientific Progress and Authoritativ Opinions in all branches of Medicin and Surgery, drawn from journals, monographs, and text-books of the leading American and foreign authors and investigators. Arranged, with critical editorial comments by eminent American specialists, under the editorial charge of George M. Gould, A.M., M.D. In two volumes-Volume I, including General Medicin, octavo, 700 pages, fully illustrated; Volume II, General Surgery, octavo, 670 pages, fully illustrated. Philadelphia, New York, London: W. B. Saunders & Co., 1903 Per volume: Cloth, $3.00 net. Half mo rocco, $3.75 net. We do not know of any similar publication, either American or foreign, that can compete in any way with this excellent Year-Book. Every new theory and scientific discovery worthy of consideration is here given. The volumes will be sold separately if desired. There are eleven full-page inserts, besides many excellent text-cuts. Laws (abstract) Regulating the Practise of Medicin in the Various States and Territories of the United States. Publisht by the Journal of the American Medical Association, 103 Dearborn Avenue, Chicago. Paper cover; 56 pages. Price, 25 cents. This little book was much needed. We get many inquiries regarding the medical laws of certain states. Here is an answer for all the states, and for only 25 cents. So we hope that all who wish such information will send for this book instead of writing to us. Memoranda of Poisons. By Thomas Hawkes Tanner, M.D., F.L.S. Ninth revised edition by Henry Leffmann, A.M., M.D., Professor of Chemistry in the Woman's Medical College of Philadelphia, Professor of Chemistry in the Wagner Free Institute of Science, etc. Publisht by P. Blakiston's Son & Co., 1012 Walnut street, Philadelphia, Pa. Price not stated. This little book contains 171 pages and is of convenient pocket size. It is not intended as a medico-legal reference work, but as a convenient pocket manual for pressing emergencies. It is up to date and incorporates all one needs to know quickly. It has a concise and quick-working index. This edition has been improved by the removal of obsolete matter and improvement in chemical nomenclature. It gives some space to food poisoning. It was always a valuable little work and this is the best of all the editions.-A. L. R. A Pocket Text-Book of Materia Medica, Therapeutics, Prescription Writing, Medical Latin and Medical Pharmacy. By William Schleif, Ph.G., M.D, Instructor in Pharmacy in the University of Pennsylvania. New (second) edition, Revised and enlarged. In one 12mo volume of 382 pages. Lea's Series of Pocket Text-Books. Edited by Bern B. Gallaudet, M.D. Cloth, $1.75 net. Limp leather, $2.25 net. This book has condensed essentials, yet gives a comprehensiv view of the same. Many facts seldom found in books of this class have been groupt here in convenient form. The articles on practical anesthesia, medical Latin, medical pharmacy, and prescription writing will be appreciated by many students and practicians. Tables of doses; incompatibles; poisons and their antidotes; a therapeutic index of diseases and remedies, and a really good index go to complete a work without a peer in its class. The long experience of Dr. Schleif has fitted him to know the needs of the student and the omissions common in many books. The book is therefore complete and particularly adapted to those who require such an aid and reference volume. It is handsomely bound, and in every way a credit to the author and publisher.-A. L. R. Spectacles and Eyeglasses: Their Forms, Mounting and Proper Adjustment. By R. J. Phillips, M.D., Ophthalmologist Presbyterian Orphanage, late Adjunct Professor of Diseases of the Eye, Philadelphia Polyclinic and College for Graduates in Medicin, etc. Third edition, revised, with 52 illustrations. Publisht by P. Blakiston's Son & Co., Philadelphia, Pa. Price, $1.00. This little work of 105 pages covers a field almost totally neglected by books on refraction, yet which is of great importance to both the ophthalmologist and the (Continued over next leaf.) HALF INTEREST in 83,000 cash practise to young married man buying half office equipment. City 9,000 population. Charles Griffith, General Delivery, Kansas City, Mo. Fo OR SALE-Medical practise in eastern Iowa. Rich country. For particulars, address G. W. Lee, M.D., McCausland, Iowa. FOR SALE-At a sacrifice, a very fine microscope which cost $125. Address L. B. Battin, Elizabeth, N. J. 7-boodings, tw. Town of 500, ane country, no op -ROOM residence, two-room office, barn, buggy shed, out position. Address Dr. N., Box 54, Browns, Ill. LOCATION OR PARTNERSHIP WANTED Twenty years' experience. Regular-Univ. of Pa., best reference. Must bear strict investigation. Address "Business," care of MEDICAL WORLD. Circulation: April, 35,656. THE MEDICAL WORLD The knowledge that a man can use is the only real knowledge; the only knowledge that has life and growth in it and converts itself into practical power. The rest hangs like dust about the brain, or dries like raindrops off the stones.-FROude. The Medical World C. F. TAYLOR, M.D., Editor and Publisher A. L. RUSSELL, M.D., Assistant Editor SUBSCRIPTION RATES: To any part of the United States, Canada, and Mexico, ONE DOLLAR per year, or FOUR YEARS for THREE DOLLARS; to England and the British Colonies, FIVE SHILLINGS SIX PENCE per year; to other foreign countries in the Postal Union, the equivalent of 5s. 6d. Postage free. Single copies, TEN CENTS. These rates are due in advance. HOW TO REMIT: For their own protection we advise that our patrons remit in a safe way, such as by postal money order, express order, check, draft, or registered mail. Currency sent by ordinary mail usually reaches its destination safely, but money so sent must be at the risk of the sender. We cannot always supply back numbers. Should a number fail to reach a subscriber, we will supply another, if notified before the end of the month. Notify us promptly of any change of address, mentioning both old and new addresses. If you want your subscription stopt at expiration of the time paid for, kindly notify us, as in the absence of such notice we will understand that it is the subscriber's pleasure that the subscription be continued, and we will act accordingly. Pay no money to agents unless publisher's receipt is given. Language is a growth rather than a creation. The growth of our vocabulary is seen in the vast increase in the size of our dictionaries during the past century. This growth is not only in amount, but among other elements of growth the written forms of words are becoming simpler and more uniform. For example, compare Eng lish spelling of a centnry or two centuries ago with that of to-day! It is our duty to encourage and advance the movement toward simple, uniform and rational spelling. See the recommendations of the Philological Society of London, and of the American Philo. logical Association, and list of amended spellings, publisht in the Century Dictionary (following the letter z) and also in the Standard Dictionary, Webster's Dictionary, and other authoritativ works on language. The tendency is to drop silent letters in some of the most flagrant instances, as ugh from though, etc., change ed tot in most places where so pronounced (where it does not affect the preceding sound), etc. The National Educational Association, consisting of ten thousand teachers, recommends the following: "At a meeting of the Board of Directors of the National Educational Association held in Washington, D. C., July 7, 1898, the action of the Department of Superintendence was approved, and the list of words with simplified spelling adopted for use in all publications of the National Educational Association as follows: securing the general adoption of the suggested amendments →→ IRVING SHEPARD, Secreta y.' We feel it a duty to recognize the above tendency, and to adopt it in a reasonable degree. We are also disposed to add enu! (enough) to the above list, and to conservativly adopt the follow ing rule recommended by the American Philological Association: Drop final "e" in such words as "definite," "infinite," "favorite," etc., when the preceding vowel is short. Thus, spell opposit," preterit," "hypocrit," "requisit," etc. When the preceding vowel is long, as in " polite," finite," unite," etc., retain present forms unchanged. We simply wish to do our duty in aiding to simplify and ration alize our universal instrument-language. The Relation of Flies to the Dissemination of Disease. Even ancient medical writers discust the influence of flies and other insects as disseminators of disease, but lacking any knowledge of bacteriology, the assertions could not be supported by proof, and hence received little attention. Nott, however, in 1848, suggested the mosquito as a cause of malaria and yellow fever, and Finlay, in 1881, asserted that yellow fever was transmitted from infected to noninfected men by flies and mosquitos, but it was not until in the '90's that these assertions were thoroly demonstrated to be facts. the probability was strongly urged as early as 1892 that cholera, dysentery, and typhoid fever were transmissible and transmitted by flies, it was not until the terrible onslaught of typhoid fever in our great military camps in the southern states in 1898 that careful and systematic investigation seemed to furnish conclusiv evidence that the fly was responsible for the widespread contagion. Altho A glance at the fly, even without the aid of the microscope, reveals immediately his wonderful capacity for conveying germs and putrescent material from infected to noninfected sources. The feet, legs, body, and proboscis are admirably adapted for this evil work. The well-known filthy habits of flies, the rapid movement of which they are capable, the extreme difficulty of excluding them from access to food, patients, dwellings, and hospitals, all combine to make them objects of dread to any who spend any thought on the matter. The fly may speedily transfer himself from a hearty meal upon typhoid dejecta, or a gangrenous or suppurating wound, or decaying offal, and, with the remains of his repast in abundant evi dence all over his body, alight upon your butter, or fall into your coffee. Not only is their capacity for carrying germs and filth by mere contact interesting, but the problem as to whether or not their dejecta may carry and store infectious germs is a vital point for consideration. It has been found that flies feeding upon certain germs may carry them in the digestiv apparatus many days and then void them in the stool not only unchanged, but in an excellent media for preservation, a fount of dissemination: thus is developt another source of danger. Sawtchenko has conducted some conclusiv experiments with flies as conservators and disseminators of the cholera germ. The flies were confined and fed only on pure cultures of the cholera spirillum. Two varieties of flies were used. The bacilli were found in the bowels and excreta four days after ingestion; and, removed on the third day and injected into guinea pigs, were found to be as activ as the pure cultures themselves. Identical results were obtained with flies fed only upon the dejecta of human cholera patients. The experiments indicated that the germ multiplied within the fly, which thus acts as an incubator and distributing agent at the same time. A fly captured in the dissecting-room during the great cholera epidemic in Hamburg, in 1892, when examined by Simmons, yielded abundant cholera bacilli. Experiments were then conducted to ascertain how long the poison could retain its toxicity when adherent to flying insects, and results proved that it was virulent for at least an hour and a half after being dried. Uffelmann, in 1892, allowed a cholera infected fly to drink once from a vessel of steril milk; the milk was then shaken and kept at a temperature of 70° F. for sixteen hours, when each drop was found to contain about 100 bacilli. Yersin, in 1894, noting the prevalence of dead flies about the autopsy tables of subjects dead of plague, crusht a fly and inoculated a guinea pig with it, and obtained the typical disease in forty-eight hours. Later, the bacilli were found in the intestins of a living fly, and Nuttall proved that not only do they carry the disease, but that in their bodies the germs multiply, and that in time the fly himself dies with the disease, and leaves his body as a still further source of infection. Plague and cholera are merely taken as instances of the possibilities of which the fly is capable. It is well known that many other germs are much more resistant to drying, heat, cold, exposure, digestion, and destruction by any agent than are those of cholera or plague. Flies are plentiful in every section of the world, and are hence a greater source of aggregate danger than the rarer diseases cited. The eggs of the common house fly are often found in the alimentary tract of mankind, and have been demonstrated in his freshly voided stool, and in the vomit; these, too, are probably a further source of infection. Cholera, taken as a type, merely indicates the almost limitless field of the evil influence of which the fly is capable. Not only does the pest carry and harbor living germs but he is also a carrier of eggs of other pests, such as tapeworm, tricocephalus dispar, the common round bowel worm and other parasites; and he carries and distributes with equal facility and impartiality the parasites responsible for malaria, filariasis, yellow fever, etc. Even the lay reader who thinks a moment upon this matter must become imprest with the momentous responsibility he incurs when he tolerates the presence of the fly about his person or dwelling. How much greater the responsibility of the physician who either does not know enuf to warn the ignorant of this danger, or who is careless enuf to neglect doing so. And not only should the moral responsibility be considered, but also the actual and proven danger be always remembered. The list of diseases which the fly is now known to transmit with facility, and perhaps to nurture into still greater virulence in transit, is a long one; and further investigation will probably add to the number of diseases. The following are already proven : Anthrax, or lump jaw, from cattle to man and vice versa, or from man to man. Cholera, from animal to man, or man to animal, or man to man. Consumption, from man to man, or from animal to man, or vice versa. Diphtheria, from man to man. Filiariasis, from man to man, animal to man, and vice versa. Gastro-intestinal diseases of various kinds, from man to man. Malaria, from man to man, or from decaying vegetable matter to man. Ocular affections of many kinds, from man to man. Plague, from man to man, or animal to man, and vice versa. Typhoid fever, from man to man, or from putrid material to man. Various intestinal parasites from man to man, or animal to man. Wound infection, including suppuration, and probably gangrene and tetanus (lock-jaw). Yellow fever, man to man. This by no means completes the list, but is sufficient warrant for our admonition. We merely hint as to the possibilities of the transmission of gonorrhea, syphilis, skin diseases, cancer, small-pox, etc. We hope that the WORLD readers will see the importance of keeping flies away from their patients and their patient's food, and their patient's wounds; and that even the busiest doctor may find time to do some brief and effectiv missionary work toward protecting human kind from the noxious pest. Investments Again. In spite of all that we said last summer about investments in stocks, we still get solicitations for advice. Now, we never offered to give private advice, and we do not wish to be bothered in this way. Also, we have not assumed to give advice concerning any particular company. Our advice was general, leaving the readers to make the application as they see fit. We are now askt (by a Pennsylvania doctor) concerning the stock of a cattle company in the far west. Don't you think it is unreasonable to expect us to keep posted concerning every company in this great country, give free advice, and then get "ballyhoo" if things if things don't come out as we predict? nd don't you think it absurd for a western cattle company to seek funds from physicians in Pennsylvania? Always look out for the concern that is after the small investor, playing on his lack of knowledge and experience, and tempting him by promises of great returns. Large investors make investments a serious, earnest business, and employ experienced talent to make investigations for them. Hence they cannot be duped easily. But the small investor supplies a never failing harvest for the cunning. Chief among these small investors that unfailingly respond to the "blandishments" of the promoters are doctors, preachers and teachersclasses that ought to know better, but they don't. Many of these, while superior in their profession and in general intelligence, are the merest children in business matters, particularly in the application of general business principles to matters unfamiliar to them. have been trying to protect the savings of WORLD readers. If any further advice is needed, all we can say is, read the issues of THE WORLD for last summer, beginning with April, and think. Worms. We Practicians of extended experience say that cases of worms are now much less frequently seen than in former days of practise. This statement is undoubtedly true. We have no theory to advance regarding the cause of the fact, but we have some suggestions relating to the rational treatment of the condition when it actually does exist. Too many practicians have but the one method of attack for all varieties of worms; hence it is small wonder that the laity are liberal patronizers of the proprietary nostrums, which, however toxic they may be, generally carry with them the power of demonstrable efficiency in selected cases. Since it is the round worm which occurs most frequently to the mind of the prospectiv purchaser, and since santonin is the most efficient drug to employ against this parasite, the proprietary preparations generally contain considerable quantities of this drug. The proper treatment by which to attack the various varieties of worms depends altogether upon the variety of worm infesting the gastrointestinal tract. Santonin never incommodes the tapeworm, and is one of the most uncertain agents by which to attack the seat or pinworm; but it is the remedy par excellence for the round worm. Outside these three worms, other varieties may be disregarded in selection of remedies, as every other variety will succumb to remedies efficient against one of these three classes. The round worm and tapeworm are to be attackt by the way of the mouth, and the pinworm by way of the bowel. To insure success in treatment of either the round or the tapeworm, it is essential that the patient fast for 12 to 24 hours in order that little food remain in the intestinal canal to serve as protection for the worm; after the fast the medicin is taken, and a few hours after the medicin a purge should be administered to flush out the canal while the worm is stupefied and unable to retain his lodgment. Fluid extract spigelia, a dram for a child two years old; fluid extract of spigelia and senna, two or three drams in divided doses to a child of same age; oil of chenopodium, 5 to 20 drops on sugar; and santonin, 4 to 1⁄2 grain of the crystals for a child, and 2 to 4 grains to an adult, are the approved remedies for the round worm. The spigelia should be followed in four hours by the purgativ, while the santonica preparations may be allowed to remain six hours before administering the cathartic. The purge should be a quick acting one like castor oil or salts. Pelletierin, 3 to 5 grains, in capsules; pulverized pumpkin seeds, after removal of the shell, and mixt with sugar, two ounces at a dose; aspidium, or oleo resin of male fern in 1⁄2 to dram doses; followed by a calomel or saline purge, make up the list of proven value in tapeworm. The male fern should not be followed by castor oil as a purge, since the oil aids in solubility of the tenacide and increases the liability to toxic symptoms. Calomel is the purge to be selected for the tapeworm. The seat-worm is best removed by quassia. Make an infusion of quassia chips, two ounces, and water one pint; inject 1⁄2 pint into the rectum after it has been cleared of feces by an enema of glycerin and water, or soap and water. The quassia infusion is retained as long as possible by pressing against the anus. If this remedy fails, either there are no pinworms present or the fluids have not reacht them. In some cases they infest the colon high up, and it is necessary to use a rectal tube |