"Dans la petite vérolc, l'éruption, la suppuration et la dessiccation forment trois périodes successives, bien distinctes l'une de l'autre par la durée, la première de trois jours, les deux autres de cinq jours cha. cune, ou environ.

"Dans la vérolette, ces trois périodes semblent se confondre, soit parce que leur durée n'excède pas six ou huit jours, soit parce qu'elles se manifestent à-la.fois, et qu'il résulte de cette intermixtion que beaucoup de pustules sont déjà sèches sur différentes parties du corps, pendant qu'on en voit d'autres en pleine maturité ou même naissantes.

"Dans la petite vérole, il survient avant l'exsiccation un gonfiement général de la peau, sensible sur-tout à la face, aux mains, et quelque fois tellement marqué aux paupières, que les malades peuvent ètre momentanément privés de voir la lumière.

"Dans la vérolette, le desséchement n'est précédé d'aucun gonfiement, ou du moins il est presque insensible.

"Un des caractères les plus notables de la petite verole, est cette rougeur prononcée que conservent pendant long-temps, sur la figure, les individus qui viennent d'en être atteints, tandis que les marques laissées sur la peau par la vérolette, sont à peine rouges, ou que les rougeurs, si elles sont apparentes, ne tardent pas à s'effacer.

Les cicatrices que laisse la petite vérole, sont plus ou moins profondes; teur surface est inégale.

"Dans la vérolette, elles n'offrent point d'inégalités, et sont plus ou moins lisses ou unies; différences qui doivent résulter de celles que présente l'état inflammatoire dans l'une et l'autre éruption.

"Enfin, la petite vérole, mème discrète et de moyenne intensité, est une maladie qui dure quinze ou vingt jours, et dont l'issue est quelquefois funeste.

"La vérolette, au contraire, se termine quelquefois en cinq ou six jours, ou huit ou dix au plus, et personne n'en a jamais été victime.

"Telles sont les différences essentielles qui établissent entre les deux maladies une ligne évidente de démarcation, à l'aide de laquelle on doit nécessairement se garantir de toute erreur; différences qui, abstraction faite de la nécessité qu'il y a d'en savoir bien faire la dis. tinction, pour être en état de répondre aux attaques dirigées contre la vaccine, ont toujours été importantes à reconnaître, puisqu'on a vu autrefois des individus, trompés par l'idée qu'ils avaient d'avoir été soumis à l'invasion de la petite vérole, se dispenser de chercher dans Pinoculation de cette maladie un préservatif coutre ses coups meurtriers, et payer de leur vie cette fatale persuasion."

But, after all, where is the triumph of the antivaccinist, supposing even that all the pretended cases of reported small.pox after regular and perfect vaccination were true? Have not the advocates of the Jennerian discovery one million for every such case, in which vaccine has proved the best and the surest protection against that terrible Scourge the small-pox? Nay, is it not agreed on all hands, that, even where the natural small-pox has actually invaded a person who had been regularly vaccinated, (and such instances, well made out,

are few in number,) the disease has run its course in a milder manner than it is known to do under different circumstances, and has seldom, if ever, proved fatal to the patient? Are there not at this moment whole districts,-nay, kingdoms,-altogether free from the variolous pestilence, since the propagation of the Jennerian discovery? and what more can man expect from the work of man?

The Report is signed by Chaussier, president; Corvisart, Delasteyrie, Doussin-Dubreuil, Hallé, Huzard, Jadelot, J. J. Leroux, Parfait, Pinel, Salmade, Duchanoy, Alibert, Bourdois, Guerbois; and Husson, secretary; and is followed by an ordinance of the minister of the interior, decrecing the distribution of one premium of 3000, two of 2000, and three of 1000 francs each, to the individuals who most distinguished themselves in propagating vaccination; and the awarding of gold and silver medals, for the same reason, to upwards of two hundred persons, all of the medical profession, with one single exception.

A voluminous Table follows the Report, containing the names of the departments, their population, the number of births, of those vaccinated, those attacked with the small-pox, those rendered infirm or disfigured by that disorder, those who died of it; the proportion of vaccinations to the number of births, the names of the operators; the amount of the expenditure for promoting vaccination; and general observations. The total result taken from this Table, occupying twenty-six pages, may be collected from the following recapi tulation:

Total.... 27,135,119 1,558,139 868,455 95,975 6,656 12,857 1 in 14

Amount of expences in 1818.... 95,292,57

the two years

....

1819....101,914,33198,206,90 fr.

Medical and Physical Entelligence.

ROYAL Society of Medicine at Marseilles.-A PRIZE question, for a golden medal, has been proposed for the year 1822, by the above Society, on the two following subjects:-1. To determine the structure and functions of the spinal marrow. 2. To describe the na

ture, causes, symptoms, and treatment, of the diseases by which the spinal marrow is affected. The Society desires that clinical observation and pathological anatomy should be made the principal objects of the memoirs on these questions. They may be written either in Latin or French; and must be addressed, before the 1st of July, 1822, to the Secretary of the Society.

Medical Funeral.-THE celebrated CORVISART, well known by his writings to the English faculty, recently died. The following account of his funeral, which we extract from the Journal des Debals of the 22d September, may interest our medical readers :

:

"The obsequies of M. le Baron de Corvisart, physician, took place to-day. In pursuance of the directions contained in his Will, his body was not taken to the church of St. Elizabeth, his parish, but was conveyed to his estate at Atys, where he desired that the religious ceremonies should be performed. A deputation from the Faculty of Medicine, in their doctor's robes, (en habit doctoral,) and nearly all the physicians of Paris, repaired this morning to his late residence, Rue de Vendome, for the purpose of attending his funeral. Mr. LEROUX, doyen of the physicians of Paris, pronounced a discourse over his coffin. The body, covered with the mantle of a doctor, and with the different orders which had been conferred upon the deceased, was afterwards placed in a hearse, to be taken to its destination, whi ther the deputation of the Faculty, and a great number of other persons, accompanied it.”

Origin of Vegetables. - TURNIPS and carrots are thought indigenous roots of France; our cauliflowers came from Cyprus; our artichokes from Sicily; lettuce from Cos, a name corrupted into Gause; shallots, or eschallots, from Ascalon; the cherry and filbert are from Pontus; the citron from Media; the chestnut from Castana, in Asia Minor; the peach and the walnut from Persia; the plum from Syria; the pomegranate from Cyprus; the quince from Sidon; the olive and fig from Greece, as are the best apples and pears, though also found wild in France, and even here; the apricot is from Armenia.

Benzoic Acid.-Mr. ORGEL has ascertained that the petals of the melilotus officinalis contain a considerable quantity of benzoic acid, which might be extracted from them with equal facility and advantage. -Tablettes Universelles, Mai 1821.

Nitrate of Potass.—Mr. TORDEUX, an apothecary at Cambrai,has had occasion to examine some hexaedral and circular crystals, which he found in a mass of the extract of cochlearia officinalis that had been lying.by for a considerable length of time. They consisted of nitrate of potash, which salt Mr. Tordeux has since been able to obtain from the same plant, by means of subacetate of lead, sulphuric acid, and concentrated alcohol. The presence of nitrate of potash in the cochlearia would explain the diuretic properties which that plant is known to possess.-Memoire de la Societé de Cambrai.

Double Fetus.-TWIN children, closely connected at the chest, are said to be in the possession of Mr. JAMES BARTON, Dale End, Birmingham, and are in the highest state of preservation. There is only one set of organs to both children. They are of the usual size of

children at nine months.-Correspondent.

Singular Fetus.-A MALE child was born, in May last, at the Hospital of la Maternité at Paris, with the whole surface of the body deeply wrinkled like that of a very old man. Its hands and feet are double the ordinary length, and are equally wrinkled. It has strong

grey hair, and a beard of the same colour. In every other respect it enjoys perfect health, and is nursed in the hospital.-Tablettes Universelles.

Medeography.-THREE vegetable productions, which might be advantageously employed in the practice of medicine, have been recently imported by Mr. DESMOGES from Senegambia. 1. The anadec, a wood which the natives of Cape Vert Islands boil with rice, and employ with great success in cases of dysentery. 2. The lémé lémé, a violent purgative, the use of which is pretty general among the negroes of that part of the coast. It is burnt and reduced to powder, like coffee. A tea-spoonful of the powder, taken in a glass of water, is the ordinary dose. 3. The bougaune, the fruit of a tree which grows in Gazamarne and the neighbourhood of Joal. When boiled, it is looked upon as a specific remedy against the colic.-Tablettes Universelles.

Accidental Poisoning by Oxymuriate of Lime.-On Friday sennight, an infant child of Mr. RICHARDS, of Chester, who had been left in charge of a servant-girl by its parents during the early part of the evening, having become very cross and uneasy, the girl teok from the cupboard what she supposed to be a cordial occasionally given to the child, and administered a small portion of it. The infant presently became more violently affected, and remained in that state until the arrival of the mother, who, on being shown the bottle by the servant, immediately discovered the supposed cordial to be a poisonous mixture, called "bleaching liquid." Medical assistance was instantly summoned, but in vain. The infant continued to labour under excruciating agony; convulsions ensued, and about midnight it expired.

Polyphagia.-AN American paper reports the death of a man, of whom several accounts have been recently published of his swallowing jack knives, bullets, marble, &c. On opening his body, twelve knives (all shut) were found in his stomach, one of them four inches and a half in length, and one a quarter wide; and among them the pocket-knife of the Philadelphia physician who had attended him. An authentic and detailed report of this very remarkable case will shortly appear in the American Medical Repository.

Periodical Medical Publication in Spain.-A Medical Journal, to be published every ten days, has been announced at Madrid, under the title of "Las Decadas Medico Quirurgicas. The objects of this periodical miscellany, are-1. To inform the profession and the public of all the discoveries and interesting facts relating to medicine and surgery in Spain and in foreign countries. 2. To give an impartial account of modern theories, medical doctrines, &c. 3. To convey. intelligence respecting all endemic discases. 4. An account of extraordinary cures. 5. Miscellaneous queries and observations, with an analysis of medical publications appearing in Spain, including the more important ones published among foreign nations. On receiving the above announcement, we immediately wrote to our correspondent at Madrid to supply us with the work, without loss of time, for the use of the Medical and Physical Journal.

Dr. Jackson and Dr. James Johnson.-Dr. JOHNSON, of Spring Gardens, has addressed a letter to the Editor of one of the evening papers, on the subject of the yellow-fever now ravaging the southern coasts of Spain. We transcribe it without a comment.

THE PRESENT EPIDEMIA IN SPAIN.

To the Editor of the Courier.

Spring Gardens; Oct. 8. SIR,-At a time when a most fatal pestilence is ravaging the southern coasts of Spain, and exciting such terror in the neighbouring states as to induce them to put in force the most rigid quarantine discipline, it may not be uninteresting to the British public to know that a countryman of their own, the veteran Dr. Jackson, now, I believe, on the verge of seventy, went voluntarily, and at his own expence, last year (1820), to the scene of this fever's devastations, in order to ascertain whether or not it was contagious, and what were the most effectual modes of treatment. He has just published a volume, containing very curious and important observations on this dreaded epidemic. It is a consolation to know that this very able and experienced physician has proved, very satisfactorily, that the disease is of a local origin; that it never was imported into those countries where it now rages; nor is it possible, almost, that it should ever be transported thence to any distance among the states in its vicinity. Popular prejudice having assigned the disease a foreign origin, popular terror has clothed it in properties of the most virulent contagion; and this last