2. The symptoms of induced thyroidism are manifestations of an intoxication resulting from the ingestion of decomposed thyroid material, a conclusion that agrees in part with the previously related observations of Lanz.

3. The so-called experimental thyroidism is not specific for the thyroid alone, for the ingestion of many substances derived from animal tissues other than the thyroid gland may produce an intoxication strikingly similar in every respect to that of experimental thyroidism.

4. Most, if not all, animal tissues yield substances which, if injected in large quantities directly into the circulation or beneath the skin, will produce an intoxication often very similar to that produced by injections of various substances derived from the fresh thyroid tissue.

5. The effects resulting from the intravascular or subcutaneous injections of aqueous extracts, decoctions, and concentrated extractives of the thyroid tissue, of the thymus, of muscle, etc., are by no means necessarily indicative of the function and the action of the hypothetical internal secretions of the same tissues during life.

6. The utilization of the fact that ingestion of decomposed thyroid material produces on certain occasions an intoxication with certain symptoms similar to those of Graves' disease is not justifiable for the furtherance of the theory that the symptoms of exophthalmic goitre result from an overproduction of the thyroid secretion.

7. Our results lead us to conclude with Drechsel that the fresh thyroid tissue yields at least probably two substances that are capable of palliating the symptoms of the acute cachexia in totally thyroidless dogs.

8. The thymus tissue also yields one and probably two substances that are equally as capable as the thyroid extractives of palliating the acute cachexia of totally thyroidless dogs.

9. Neither of the above substances is an enzyme, nor does either contain iodine.

10. Neither the feeding of minced raw thyroid glands, nor the injection of aqueous thyroid extracts, decoctions, and concentrated solutions of the extracted palliative thyroid principles is capable of keeping totally thyroidless young dogs alive longer than a few weeks (possibly three weeks). Still less capable are the thyroid preparations containing decomposition products.

11. The presence of one, or unusually several, small accessory thyroid bodies, which gradually hypertrophy and wholly or partially assume the functions of the excised thyroid lobes, accounts for the occasionally long survival of thyroidectomized, thyroid-fed young dogs.

12. Totally thyroidless young dogs are so quickly overwhelmed by the cachexia, and the intervals between the thyroidectomy and the onset of the severe dyspneic attacks, and subsequent deaths differ so slightly, no matter which of the usual varieties of fresh food is employed, that kinds of fresh food can not be unquestionably affirmed to influence the onset of the

cachexia in any especially definite manner. Animal foods, in which constituents poisonous to rabbits have developed, probably hasten slightly the onset of the severer symptoms, and the vaunted remarkable modifying influence of a diet of ordinary milk, such as Breisacher observed, does not exist in the case of the totally thyroidless dog.

13. Monkeys whose general metabolism is disturbed in consequence of the removal of a greater portion of the thyroid gland, evidently become more susceptible to those constituents of meat that are poisonous to rabbits, and sufficient clinical evidence exists for concluding that probably a like susceptibility to animal foods containing such constituents also exists in men when the function of the thyroid gland is sufficiently.disturbed.

14. And, finally, as regards the thyroid factor in the pathology of exophthalmic goitre, the writer agrees with Gley, that the majority of the symptoms in many patients with that disease can apparently, from an experimental standpoint, be as plausibly explained by the hypothesis of partially deficient thyroid activity as by the hypothesis of augmentation of thyroid function.-Medical Record.

THE FIRST NATHAN LEWIS Hatfield PriZE FOR ORIGINAL Research IN MEDICINE.-The College of Physicians of Philadelphia announces through its committee that the sum of five hundred dollars will be awarded to the author of the best essay in competition for the above prize.

Subject: "A Pathological and Clinical Study of the Thymus Gland and its Relations."

Essays must be submitted on or before January 1, 1900.

Each essay must be typewritten, designated by a motto or device, and accompanied by a sealed envelope bearing the same motto or device and containing the name and address of the author. No envelope will be opened except that which accompanies the successful essay.

The committee will return the unsuccessful essays if reclaimed by their respective writers or their agents within one year.

The committee reserve the right not to make an award if no essay submitted is considered worthy of the prize.

The treatment of the subject must, in accordance with the conditions of the Trust, embody original observations or researches or original deductions.

The competition shall be open to members of the medical profession and men of science in the United States.

The original of the successful essay shall become the property of the College of Physicians.

The trustees shall have full control of the publication of the memorial essay. It shall be published in the Transactions of the College, and also when expedient as a separate issue.

Address J. C. Wilson, M. D., Chairman, College of Physicians, 219 South Thirteenth Street, Philadelphia, Pa,

OFFICE OF THE STATE BOARD OF HEALTH,

BOWLING GREEN, KY., June 21, 1898. }

To Osteopaths and all Other Unlicensed Practitioners of the Healing Art in Kentucky: Gentlemen: Notice is hereby given that this Board will hold an examination of applicants for license to practice the healing art "by any system or method whatsoever" at the University of Louisville, in the city of Louisville, beginning at 9 A. M., Tuesday, July 5, 1898.

The examination will be open to all bona-fide residents of the State who are graduates from schools of osteopathy, from medical schools whose standing has not been heretofore fixed by the Board, and to all reputable non-graduates who were reputably and honorably engaged in the practice of medicine in this State prior to February 23, 1884, who can furnish the proof required by the statutes.

The examination will be limited to the branches taught in such schools at the time the particular applicant graduated, will be entirely in writing, and while practical in character will be sufficiently thorough to fully and fairly test the capacity of each applicant. The Board wants every competent applicant to obtain a license, and no one should ask more than this. As the Board does not contemplate another examination for graduates from schools now represented in this State, or for non-graduates, it is earnestly requested that all applicants be on hand promptly at the hour named.

By order of the Board.

J. N. MCCORMACK, M. D., Secretary.

J. M. MATHEWS, M. D., President.

THE ROENTGEN RAYS IN WARFARE.-Surgeon-Major W. C. Beevor, M. B., Army Medical Staff, gave an address on this subject at a meeting of the Royal United Service Institution on May 20th. The chair was taken by the Director-General, and the paper was concerned especially with the employment of the Roentgen rays during the recent operations on the frontier of India. Surgeon-Major Beevor observed that one of the greatest desiderata in the construction of all apparatus for military work was that every portion of the apparatus should be easy of access, so that repairs could be made, while at the same time the whole could be quickly packed and unpacked in cases suitable for transport under the very rough conditions of actual warfare in mountainous countries. It appears that the apparatus used during the frontier expedition consisted of a 10-inch spark coil, a primary battery, three tubes, a screen, and some Paget photographic plates. The lecturer showed a compact and portable wooden box, into which a serviceable folding tube holder and a screen could be packed. He showed also a vulcanite box with a handle to take a Crookes' tube, to which insulated electrodes could be attached. This could be freely moved about and placed in any position necessary for the examination of the patient with the screen. Surgeon-Major Beevor contended that it was the duty of every civilized nation to supply apparatus for the Roentgen rays

not only at base hospitals, but also at every point where soldiers were fighting and exposing themselves to injury in the performance of their hazardous duties. The portable apparatus should not weigh more than eighty to one hundred pounds, and could then be carried slung from a pole by two men. Transport by mules, camels, or wheeled vehicles was too uncertain a means of conveyance for delicate apparatus except where there were good roads. A difficulty which had been met with was that a hot sun might melt the wax which insulated the wire of the secondary coil. It was found that a mixture of paraffin wax and resin which did not melt under 150° F. was enough for all practical purposes, while a covering of felt protected the coil from sun, rain, snow, and frost. The screen, which was a most important part of the apparatus for urgent cases, could be inclosed in an aluminium case and protected from accidental scratches by a layer of celanite, as suggested by M. Laconteur, of the London Photographic Asso ciation. Surgeon-Major Beevor's paper was a valuable contribution toward the practical working out of the best apparatus for use in emergencies in the field, and those who have had experience of the difficulties which arise even in the best appointed laboratories will be best able to form an opinion as to the serious character of the obstacles likely to be encountered under limited conditions.-British Medical Journal.

RESOLUTIONS.-Whereas, In the providence of an All Wise and Loving Creator, our beloved president, John A. Larrabee, has been removed from his sphere of earthly labors, it is hereby

Resolved, That we, the members of the Senior Class of the Hospital College of Medicine, recognize in the death of Prof. John A. Larrabee that the profession has lost one of its most progressive members, and one whose labors have added much to the common stock of knowledge.

Resolved. That the Faculty has lost a most efficient member and leader, and the students have lost an able and beloved instructor.

Resolved, That the community and the many institutions in which he has labored so long and faithfully will keenly feel the loss caused by his death.

Resolved, That the little children of the city have lost a loving friend whose testimony was: that his highest pleasure was in alleviating their sufferings.

Resolved, That we extend our heartfelt sympathy to the bereaved family and friends.

Resolved, That a copy of these resolutions be sent to the family, and a copy be spread upon the records of the class, and printed in the local papers and medical journals.

J. A. NELSON,
ROY L. CARTER,

LOUISVILLE, KY., June 15, 1898,

UNION T. TAYLOR,

CHAS. G. STEVENSON,

WYLIE H. FORSYTHE,

Committee.

THE AMERICAN MEDICAL TEMPERANCE ASSOCIATION.-The annual meeting of this association will be held in this city at Prohibition Park, Borough of Richmond, on July 5th and 6th. Papers have been promised by Drs. T. H. Manley, D. H. Mann, J. J. Morisy, and Ira Van Gieson, of New York, W. Van R. Blighton, of Buffalo, M. H. Hunt, of Boston, F. Horner, of Marshall, Va., Norman Kerr and Sims Woodhead, of London, and Sagrund, of Paris. The following are the officers of the association : President, N. S. Davis, Chicago, Ill.; Vice-Presidents, J. B. Whiting, Janesville, Wis.; F. E. Yoakum, Shreveport, La.; J. Taft, Cincinnati, Ohio; Secretary, T. D. Carothers, Hartford, Conn.; Corresponding Secretary, J. H. Kellogg, Battle Creek, Mich.; Treasurer, G. W. Webster, Chicago, Ill. The late Dr. Quimby, of Jersey City, was a vice-president of the society at the time of his death.-Medical Record.

CONTROL OF TUBERCULOSIS IN DENMARK.-A committee of the Danish Medical Association has caused to be distributed throughout that country placards and pamphlets giving careful instructions for the prevention of tuberculosis. The placards are hung up in railway carriages and stations, schools, and factories, and the pamphlets are distributed gratis in public places. A movement is on foot also for the establishment in many parts of the country of sanatoria for consumptives. The disease has been increasing at an alarming rate in Denmark, and it is hoped that these measures will be successful in restricting its spread.-Ibid.

AN EXPERIMENT IN GOVERNMENT.-The San Diego (Cal.) Medical Society has turned over a new leaf and elected the women members to fill the offices instead of men. Dr. Magee, who has been secretary for ten years, stepped out and made room for Mrs. Dr. Nelson. During the present. year the society will have a lady president, a lady vice-president, and a lady secretary.-Kansas Medical Journal.

TRAINED NURSES FOR THE ARMY AND NAVY.-A bill has been introduced in the House of Representatives by Mr. Cummings, of New York, authorizing the secretaries of war and navy to enlist one hundred female nurses for service in hospitals and hospital ships during the war with Spain. The nurses must be graduates of training schools, and will have the same pay as hospital stewards.- Medical Record.

THE next semi-annual meeting of the Mitchell District Medical Society will be held at West Baden, Indiana, July 20 and 21, 1898. Special rates at hotel for physicians and their families.

DR. U. H. HON, Corresponding Secretary.

USE OF A BROOKLYN HOSPITAL OFFERED TO THE GOVERNMENT.— The use of St. Catharine's Hospital in Brooklyn, with its mother superior, forty-five nuns, the entire hospital staff, and all the attendants, has been offered to the government. The institution is conducted by the sisters of St. Dominic.-Medical Record.