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wonderful rapidity, inasmuch as the tolerance of the stomach for nourishing food and the appetite were restored by its administration. Mariani's wine is vastly superior to the wine of quinia, since the latter by augmenting the gastro-intestinal irritation interferes with the alimentation, and consequently with repair, thereby aggravating the anæmia instead of ameliorating it.

I have also employed it in those cases of chronic alcoholism, fortunately rare in the French army, which follow the abuse of absinthe and strong liquors. Mariani's wine, while producing primarily a certain amount of cerebral stimulation, exercised a predominant sedative effect upon the nervous system. I have, moreover, witnessed the spectacle of hardened drunkards giving up their pernicious habits and returning to a normal condition under the influence of this treatment.

I have also employed Mariani's wine successfully in the treatment of the tobacco habit. A few glasses of the wine, taken in small swallows or mixed with water, were sufficient to replace both pipes and cigars, since the patients obtained the cerebral stimulation which they sought for, albeit unconsciously.

I have also employed it in chronic bronchitis, and even in pulmonary phthisis. Mariani's wine augments the appetite and diminishes the cough in both these conditions. When combating the cough I have given it mixed with water, a wine-glass of the wine to a tumbler of spring water.

Finally, I have employed it in the convalescence following typhoid fever with the greatest success, and this in cases where the irritability of the stomach was so great that no wine, not even Bordeaux, could be tolerated.

To recapitulate, I am convinced that Mariani's wine is the most potent arm which can be placed in the hands of the military surgeon for the purpose of combating the sickness, infirmities and vicious habits engendered by campaigning and the hardships of military life. I will also state that whenever any other than Mariani's preparations of coca were used, the results intended were not produced; quite the contrary; bad effects and even unpleasant complications were noticeable, and to this I call the special attention of the physician.-N. Y. Medical Monthly.

OUR ADVERTISERS.

LIEBIG PHARMACAL Co., NEW YORK.-See advertisement of this company to be found on page 26, and write them for samples of their goods.

GEORGE MUSE, ATLANTA.-This gentleman has the largest clothing store in Georgia and is a first-class man in every respect. Parties dealing with him will find him perfectly reliable. He promises to every one entire satisfaction. See his ad.

STEPHENS' SADDLE BAGS.-Observe the charge in the advertisement of Geo. K. Hopkins & Co., manufacturers of these justly celebrated bags. They are superior to any bag we know.

CODMAN & SHURTLEFF, BOSTON. This well-known house has an advertisement elsewhere in THE JOURNAL, to which we invite the attention of our readers. We shall have more to say of them in another issue. See their advertisement, and write them for any goods you may need in their line.

RECTAL ALIMENTATION.-Peptonized milk, as manufactured by Messrs. Fairchild Bros. & Foster, of New York, is said to be the ideal substance for nutritive enema. It does not irritate the bowel, is perfectly absorbable and may be used almost indefinitely without causing any local disturbance. If you have not tried it, send for samples and give it a trial. You will be pleased with it.

SUCCUS ALTERANS (MCDADE).-The late Dr. J. Marion Sims, and many other physicians of note, both in this country and Europe, have given this remedy their unqualified endorsement in the treatment of syphilis. It is manufactured by Messrs. Eli Lilly & Co., of Indianapolis, one of the best-known houses in this country. See the advertisement next to "Correspondence," and if you would know more of the remedy address the firm for

the Monographia Syphilitica for January, 1887. It is the latest publication of Dr. McDade, the gentleman who first introduced this remedy to the profession.

EISNER & MENDELSON CO., PHILADELPHIA.-These gentlemen have an attractive advertisement in this issue next to Book Reviews, to which we direct the attention of our readers. They are the sole agents for Johann Hoff's Extract of Malt, a preparation which bears the endorsement of prominent physicians everywhere. Read the advertisement and observe instructions closely, that you may always get the genuine article when you order malt extract.

PARKE, DAVIS & Co., DETROIT.-We desire to direct attention to the new advertisement of this house to be found next to clinic reports in this issue of THE JOURNAL. No house in the country makes superior pharmaceutical preparations to this one. Their name is a guarantee that the preparations manufactured by them are what is claimed for them. See their advertisement and write them for samples of any goods you may desire to test.

PEACOCK'S BROMIDES.-W. H. Wolford, M. D., Chicago, Ill., says: I have used Peacock's bromides in a number of cases with the best results, especially in epilepsy, one case in particular, C. S., a railroad man, having been compelled to quit work on account of the paroxysms coming on every day. After one week's treatment with Peacock's bromides, the attacks were considerably lessened; now, after two months' treatment, he seems entirely cured and has resumed work. Any case where there is a nerve sedative indicated I can cheerfully recommend Peacock's bromides.

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LECTURER ON OPERATIVE GYNECOLOGY, SOUTHERN MEDICAL COLLEGE, ATLANTA, GA.

There is probably no class of diseases, outside of those which are from their nature necessarily incurable, which are ordinarily treated with so little satisfaction and success as the diseases of the female bladder and urethra. One reason for this may be found in the fact that the profession has heretofore had no means of making anything like a thorough physical exploration of these organs. As the treatment of uterine diseases was little more than mere guess-work and empiricism until a new impulse was given to it by Sims' invention of the speculum which bears his name, so until recently, for lack of the means of exploring by

* Read before the Atlanta Society of Medicine, November 16, 1886.

the eye and the touch the urinary tract of women, the treatment of diseases of that tract has been one of the opprobria of gynæcology. Another reason for failure in the treatment of derange- „ ments of the female bladder lies in a lack of appreciation of the causative effect of uterine disease in these affections. Many a woman has been faithfully and persistently treated for vesical irritation with frequent micturition by astringent injections into the bladder, when the whole cause of her trouble consisted of a displacement of the womb which produced a traction upon the vesical neck which could be remedied only by lifting the womb to its normal position in the pelvis. A very considerable proportion of all women who are the subjects of uterine derangement suffer more or less with bladder symptoms. This is not at all strange when we remember that the bladder derives its blood supply from the same arteries as the womb, that the venous connections of the two organs are most intimate, that its nerve fibres and those of the womb are inextricably interlaced, and that its connective tissue is continuous with that of the uterus. Between two organs so closely related in every way, it is evident that an intimate sympathy must exist and such is found to be the case in actual experience. Hence any treatment of irritation of the bladder which ignores existing uterine derangements will inevitably fail to accomplish a cure. At the same time, it is true that there are many cases in which irritation of the bladder has no dependence upon disease of the womb and the recognition of the presence or absence of such a dependence is the point upon which turns success or failure in the treatment.

Frequent micturition often exists in women when there is no other subjective symptom to indicate disease. These cases are sometimes seen in practice. But it is oftener the case that such patients mutely suffer for years, heroically bearing the pain and annoyance to which they are subjected with the patient endurance characteristic of their sex. Since there is no fixed law in regard to the normal frequency of micturition, the line which separates a healthy from a pathological condition is very indefinitely drawn and women often unconsciously overstep that line and may even pass far beyond it through lack of proper physiological teaching.

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