marked, but not at all painful. Disagreeable sensation in the anus as if it were stopped up with a plug, or as if filled with wind. Hæmorrhoids. Discharge of a little blood with the stool. A proving ten years later yielded the same symptoms as above. At no time the least affection of the skin,.

Sexual Organs.-The menses came at once, out of the proper time; too early,3.

Chest.-Bruiselike pain of the muscles and bones of the chest,. Superior Extremities.-Pain extending from the left shoulder downward to the lower ribs,.-A numbness of feeling in the muscles of the arms and hands,.-Gnawing pain in the bones of the arms and hands,3. Inferior Extremities.—Itching stitches on the right shin-bone,. Generalities.-In the whole body feeling of being unwell, which causes restlessness,".

Sleep. In his sleep, he dreams that he hears music, and thereupon. awakens, and still thinks that he hears it,'.

SENEGA.

Authority. 38, E. W. Berridge, M.D., New York Journ. of Hom., vol. ii, 1875, p. 459, Miss aged twenty-one years, took several doses of em. (Fincke), for a cold and cough.

Menses came on three weeks too soon; this never happened before, even when she had a cold,38.

STRAMONIUM.

Authorities. 244, J. E. Chancellor, M.D., Virginia Med. Month., March, 1879, p. 962, a child, æt. two years and a half, drank an infusion of the seeds; 245, F. H. Underwood, M.D., Pub. Mass. Hom. Med. Soc., vol. iv, p. 355, Miss A., æt. twenty-two years, in good health, except occasional attacks of nervous restlessness, with a sensation of fear, took a gobletful warm, of a strong decoction made with boiling water.

Mind. Intoxication, with a feeling of heaviness in the body. Diminished memory; she would begin to speak of something, and before finishing would forget what she was talking about. She does everything in great haste. Her movements are all hurried. Stupefaction of the senses. All things appear to her as if they were new; even her friends appear to her as if she had never seen them before. She apprehends the loss of her senses, or that she is becoming imbecile. She has strange fancies. Frightful fancies. Her features show fright and terror. She does not dare to walk without assistance, lest she should fall. Great anxiety and fear. Restlessness and nervousness beyond description. Constant fear of sudden death. At times believed herself dying, and could not be convinced to the contrary. Great fatigue from the least exertion; when going from her bed to the door of room, only a few steps, she was obliged to sit down twice. Her whole body was sensitive to touch, and every motion aggravated. Frequent attacks of gloomy fancies, accompanied with tears,. Head.-Head feels empty, hollow, and sensitive to every sound; it is confused, and she is unable to think much or reckon. Stupid feeling of the head. Vertigo; the head feels drawn backward. Great dislike to

move about, and an inability to sit up straight any length of time. Vertigo when raising the head from the pillow. Her voice, to her, did not seem to have its usual sound; it seemed higher and finer than usual. Great heat of the head. Cold face. A disagreeable lightheadedness, with a feeling of great weakness in the head. Red rash on the face, neck, and back, which resembles that accompanying scarlet fever. Giddiness while sitting or standing in a room. Giddy headache, with faintness. Frequent inclination to raise the head from the pillow. Moves her head to and fro. Redness of the face and eyes. Frequent redness of the face. Her nose feels obstructed and dry, although she is able to breathe through it,25.

Eye.-A sensation as of sparks of fire rushing from the stomach to the eyes. Obscuration of sight; things looked blue and smoky, and at times could see only half an object at once. Redness of the eyes and face. Eyes are staring. All things look smaller, and at a greater distance than they are. Dilatation of the pupils. Extreme dilatation of the pupils. She complains that the rays of the sun dazzle her eyes. Eyes glisten. Dimness of sight; she is unable to discern small things, such as the point of a pin. Indistinct, confused sight. Fiery visions before the eyes. With staring eyes and dilated pupils she saw nothing; did not recognize any of her family. Every one's face looked to her as clear and as smooth as a piece of satin; and small spots like freckles, on a person's face, were not discernible for ten days after taking the poison,245.

245

Mouth-Tongue.-Tongue felt stiff, dry, and parched to the very root, and felt as if edges rolled up as hard and stiff as sole-leather. Tongue is paralyzed; it trembles when she attempts to put it out. Swelling of the tongue, which hangs out of the mouth. Dryness of the tongue and palate, so that they feel quite rough, with no thirst at first, General Mouth.-Sore lips; they parch up and chap, then peel. Grinding of the teeth. Bloody froth at the mouth every morning. Feeling of great dryness in the mouth, with want of saliva,.-Taste.-Water tasted like leather for three weeks. Eggs tasted like Sulphur. Food tastes bitter. Constant bitter taste in the mouth. Loss of appetite,25.

Throat.-Dryness of the throat, with a saliva like stiff froth, mixed with cotton-wool. Dryness of the throat. Strangulating sensation in the throat. Food and drink were swallowed with great difficulty, and with a scraping pain. Inability to swallow, on account of dryness of the throat, 245.

Stomach.-[1690.] Loss of appetite. Great desire for acid drinks. Sickness at the stomach, with a desire to vomit, but an inability to do so; followed by dizziness, faintness, and a difficulty in swallowing and breathing. Indescribable feeling at the stomach, followed by partial loss of consciousness. Weak feeling at the stomach, as if everything were gone. Weakness from the least exertion, vomiting of sour-smelling mucus. Sour stomach. The first food taken, which was rice-water, had no taste, and felt like apple-cores in the stomach. Stomach smarted and felt ragged, as if full of sores. Vomiting of mucus at night. Anxiety about the pit of the stomach. Anxiety about the pit of the stomach, with difficulty of breathing. A sensation of weakness so great that she could not describe it. Nausea. Bilious vomiting after the least motion,245.

Abdomen. Abdomen bloated, but not hard. Rumbling in the abdomen. Feeling in the abdomen, as if living animals were moving in it. Emission of large quantities of flatus,"".

Chest.-A feeling of great faintness, as if there were no air, or, as if

the air did her no good. Difficult breathing. Sensation as if something were turning about in the chest. She is unable to inspire a sufficient amount of air. Feeling of dryness in the chest. She has paroxysms of fainting; says she wants more air,245.

Heart and Pulse.--A sudden sensation of weakness, and violent beating of the heart. She would wake from a deep sleep with violent. beating of the heart. Pulse full and strong. Pressure in the region of the heart,245

Extremities.-Trembling and shuddering of the limbs. Limbs were paralyzed for eight hours. Hands and feet numb, or like wooden ones, or as if they did not belong to the body. Trembling of the arms when eating. Trembling of one hand when eating. Trembling of one limb. Convulsions of the limbs. The limbs feel as if gone to sleep. Drawing pain in the thighs. Sensation as if one part of the joint were separated from another. Immobility of the limbs. Creeping in the limbs. Tingling in all the limbs. Creeping extending from the left side into the thigh. When walking, although she staggers, her limbs obey the will so readily that she feels as if she had none; they seem much longer than they

Generalities.-After thirty minutes I saw her; she was lying on the bed, with her face very red, the pupils dilated; pulse full and strong; great trembling of the limbs, and frequent unsuccessful attempts to vomit. From evident paralysis of the throat she was unable to swallow enough of a mustard emetic to cause emesis. She exhibited great inclination to go to sleep, which she was prevented from doing by the attendants walking, or, I should say, dragging her about the room, her limbs being so paralyzed that she could not walk, or even stand; and she presented a most perfect picture of intoxication. The severity of the narcotism lasted about an hour, and was followed by a state of wakefulness, which lasted about twenty-four hours. During the first two weeks of her sickness, I gathered from her the symptoms, which she assured me were entirely new to her, and many of them, she has since informed me, continued her frequent companions for more than a year. The first effect of the drug she noticed about ten minutes after she had taken it,245.-Spasmodic twitchings of the muscles of the upper and lower extremities, unsteady gait and inability to stand erect, with restlessness and incoherence of speech, alternately laughing, crying, and singing; some nausea and disposition to emesis; pupils widely dilated; difficult deglutition; tumultuous action of the heart; expressions of alarm and dread of falling,"

244

Sleep.-Very drowsy. Restless sleep. While slumbering she heard two persons talk, but did not know who they were,245.

Fever.-Cold feet and hands. Slight sweat at night. Chills through the whole body, with single jerks, at times, of the whole body, and at other times of single limbs. Cold limbs. Chilliness and shuddering of the limbs at night. Fever in the afternoon. Sweat on the back. Frequent sweats. Profuse perspiration of the limbs,245.

STRYCHNINUM.

Authorities. 162, R. Gilsan, Amer. Journ. of Med. Sci., New Ser., No. 150, 1878, p. 449, a man, æt. twenty-five years, took a dose; 163, V. R. Bridges, M.D., Chicago Med. Journ. and Exam., 1879, p. 48, a girl, æt. nine years, took an unknown quantity.

I found him in terrible tetanic convulsions. His legs and arms were extended, hands clenched, feet and toes incurvated, and his body was rigidly arched backward, and resting on his heels and back of his head. In short, all his muscles seemed to be in a state of rigidity. There were also the risus sardonicus, and a general cyanosed appearance of the skin. During the paroxysm the pulse was too frequent to be counted, and his pupils were slightly dilated. It was impossible on account of trismus and the violence of the general spasms, to administer an emetic by the mouth or to use the stomach-pump. The next morning I found him well, but still feeling some muscular soreness and fatigue, and fully resolved to let Strychnia alone in the future. He said no one could imagine the fearful agony it had caused him, and that he would rather be burnt to death than again suffer the pangs that he had endured from this horrible poison. He told me also that after taking the Strychnia he locked the door of his room, and lay down on his bed to die, as he supposed, in a rapid and easy manner. When the spasms commenced they soon put him in such fearful agony that he screamed for help,16-Continuous and persistent spasm from head to foot, with an alarming and distressing opisthotonos, rendered all the more painful from the fact that she was entirely unconscious of her sufferings, while any effort to relieve her by the slightest touch, or causing her to swallow, only aggravated her condition, by apparently exciting every muscle to increase its tension,163.

SULFUR.

Authority. 78, S. Thompson, Pub. Mass. Hom. Med. Soc., vol. iv, p. 641, a policeman took 2 ounces Sulphur and molasses at one dose, for army-itch.

Within an hour he vomited, throwing the most of it out. Within five hours a diarrhoea commenced, slight nausea, painful griping and rumbling in the bowels. (I purpose to give the gastric symptoms only). These symptoms continued till the morning of the third day, when the diarrhoea became painless, and almost involuntary. The stool was light-colored, watery, and lienteric. This condition continued till the middle of the seventh day, when the discharges of the bowels stopped, and were followed by symptoms in the lungs and head,"8.

SYPHILINUM.

The matter exuding from a true chancre.
Preparation, Triturations.

Authority. H. J. Ostrom, M.D., Organon, vol. ii, 1879, p. 262, effects of 1 m.

While medicating the pellets, I was seized with oppression of the chest, to such an extent as almost to arrest breathing. The asthma was caused by a sensation as if the sternum were being gradually drawn towards the dorsal vertebræ. Expansion of the chest was difficult, because of the feeling of tightening. With this there was some confusion of mind, as if unconsciousness might follow if the dyspnoea continued. The attack lasted about ten minutes, and was followed by a general weariness, which passed off in a few hours.

TABACUM.

Authorities. 176, B. C. Brodie, Pharm. Journ., 2d Ser., vol. ii, 1860-1, p. 237, effects of smoking; 177, Wm. O'Neill, M.D., Lancet, 1879 (1), p. 296, Mrs. A., æet. forty years, applied chopped tobacco to a bleeding wound.

Extremely prostrated, pulse scarcely to be felt, skin pale, cold, and wet, with a profuse clammy perspiration. The pupils of the eyes were dilated, and in a faint whisper she complained of dizziness, of dimness of sight, and of confusion of thought, also suffered from severe pain in abdomen, constant nausea, and vomiting,".-Almost the worst case of neuralgia that ever came under my observation; the pains were universal and never absent; but during the night they were especially intense, so as almost wholly to prevent sleep,176.

TANACETUM.

Authority. 23, A. E. Spaulding, M.D., Philad. Med. Times, vol. vii, 1877, p. 467, a woman, æt. twenty-one years, took a teaspoonful of the oil to bring on the menses.

Convulsion; powerful tonic contraction of the flexor muscles, the forearms were drawn forcibly against the thorax, face deeply congested and livid, foamy saliva was ejected from the mouth, eyes were wide open, and remained so during the convulsion, which lasted from one to two minutes, 23.

TARENTULA.

J. Heber Smith, M.D., New England Med. Gaz., New Ser., vol. i, 1879, p. 139. The tarentula by which Dr. Sherman was poisoned, came through the mail, and decomposition had undoubtedly commenced at the time the virus was imbibed into the system, and hence the symptoms in his case were such as might come from the scalpel or any other kind of animal poisoning, and therefore the symptoms reported cannot be reliable. (See authority, No. 16, in Vol. IX, of the Encyclopedia.)

TRILLIUM CERNUUM.

Trillium cernuum, L.

Natural order, Trilliace.

Common name, Nodding Trillium.

Preparations, From the root.

Authority. Henry Minton, Inaug. Thesis, presented to Hom. Med. Coll. of Penn., 1853, copied from MSS.

Mind.-Melancholy, with sadness. Repugnance to conversation. Illhumored, irritable, disposed to get angry at trifling things. Afraid that he is going to be sick; great anguish; agitation and tossing about, impossibility of keeping still.

Head.-Confused head. Attacks of vertigo, with tottering. Swimming in the head. Dizziness, chiefly on rising, in the morning. Weariness