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sions (eighth day),.-I found him in the sixth convulsion, fearfully distressed, and every part of the patient was drawn up, his feet, legs, arms, and hands were closely contracted, the hands being so clasped that it was impossible for me to open one finger; face flushed a bright scarlet, cheeks and forehead hot; but around his mouth it was marble white, and under his eyes it had a purple shade; pupils dilated; eyes rolled up so that you could only see the pupils by pressing the lid up as far as possible. He remained in this condition about five minutes. After remedies he vomited fresh blood, perhaps half a teaspoonful each time, mixed with the egg. After six hours the pulse was 160, face flushed, tongue dry, with a very red streak in the centre, and very thirsty. About 12 o'clock that night blood began passing the bowels, and shreds of membrane, with great tenesmus. In the morning the stomach and bowels were sore to pressure,. She fell to the ground in a faint, became collapsed, insensible, with a very small pulse,".-First day, unconscious; pulseless at the wrist; constant restlessness and tossing about. Second day, fully conscious, but spoke with difficulty; pulse 120; myalgia. Third day, continued restlessness; pulse 120. Fourth day, pulse 100. Sixth day, pulse 80. Seventh day, pulse 88. Eighth day, pulse 88, refuses to talk. Ninth day, pulse 100. Tenth day, myalgia. Eleventh day, pulse 96. Twelfth day, pulse 100; myalgia. Thirteenth day, pulse 88. Fourteenth day, pulse 100. Sixteenth day, pulse not countable; is not inclined to talk; great debility and emaciation. Seventeenth day, had a fainting spell; heart stopped for a few seconds, her eyes half closed, and died on the seventeenth day after taking the poison,Restless (after five hours and a half),.-İn a state of almost hopeless collapse (after five hours and a half),.—[1200.] Prostration (ninth day),. Extremely prostrated (twenty-first day)," Great prostration and violent pain (fifth day),87.

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Skin. First day, the skin had a very dry, harsh feeling to the hand. Second day, great coolness of the surface all over the body. Third day, skin warm all over, but hottest on the face. Fourth day, high fever. Sixth day, great itching of the skin, which looks dry and shrivelled. This itching, with variations in the temperature, continued until death,96.

Sleep. First and second days, scarce any sleep day or night. Third day, slept a little during the daytime. Fourth day, slept better. For the next seven days she had short naps and unpleasant dreams. Fourteenth day, had very restless nights for the last three nights. Seventeenth day, sleeps with eyes half closed,.

Fever. The whole surface was cold, and bathed in a profuse clammy sweat (after half an hour),".-Skin, even when dry, felt cool to the touch (twenty-first day),".-Artificial heat was required to keep her feet and limbs warm,92. Surface and extremities cool (after five hours and a half),.-Begged for cold water often to drink, and to be poured on her body and head, and expressed partial, temporary relief when her body was sponged with cold water; saying without water, she was burning up, inside and out (twenty-first day),".-[1210.] Febrile excitement in the evening (sixth day); continued (seventh day),.-Cold sweats,".

MERCURIUS PRECIPITATUS ALBUS.

Authority. 4, Pharm. Journ., 2d Ser., vol. i, 1859-60, p. 532, Harriet Moore murdered her child with 20 grains.

Immediately after some arrowroot the child was violently sick, and during the night shrieked as though in great pain. On the following morning he was found to have undergone a remarkable change, and in the language of one of the witnesses, had become quite an "old man,”.

MERCURIUS PRECIPITATUS RUBER.

Authority. 15, F. S. Smyth, Brit. Med. Journ., 1878 (2), p. 101, poisoning of a woman æt. twenty years.

Lying upon the bed in a state of stupor, with a weak, irregular, scarcely perceptible pulse; pupils dilated, but sensible to light; the surface of the body cold and clammy to the touch, and a copious discharge running from the mouth. Had vomited, and her bowels were very loose, and she complained of great pain across the abdomen. Later she complained of cramps in the lower limbs, and severe pain in the abdomen,15.

MEZEREUM.

Authorities. 53, Lesser Writings of Hahnemann (Dr. Adolph Gerstel, North Am. Journ. of Hom., New Ser., 9, 1878, p. 184); 54, Pluskal, Oest. Woch., 1844 (ibid.), effects of leaves; 55, Dr. Schwebe, Caspar's Woch. (Lancet, 1849 (2), p. 637), two children, æt. four and two years, ate some berries; 56, J. B. Carruthers, M.D., Lancet, 1859 (2), p. 378, a child, æt. three years, ate the berries.

Somebody advised a young, pale girl, æt. fourteen years, to use the leaves of Mezereum in order to become fat and rosy. She went into the woods and made free use of them on her cheeks and surrounding parts. Burning pains soon appeared, her whole face swelled up enormously, especially the nose, eyelids, and hairy scalp. Severe and painful sneezing, deliria, dull, unbearable, pressing pains in the forehead, a nauseous dryness in the throat, and a constant irritation to dry cough, showed that the acridity of the poison by its inhalation affected the nose, and through the frontal sinuses the cerebral membranes, also pharynx and larynx. The face soon took on the expression of erysipelas bullosum, the nostrils closed, so that she could only breathe through her mouth; febrile pulse, burning urine. After external application of oil, cold compresses, and indifferent external remedies, the swelling decreased after the second day, and desquamated in large pieces. But health did not return. Debility, loss of vitality, and mental depression, bordering on idiocy, were since that time observed in her. A typhoid fever, lasting full three months, prostrated her so much that she finally succumbed to it,".-Dryness and burning of the throat, with attempts to vomit; intense thirst; great heat of skin; great prostration of strength; pale countenance; and a feeble quick pulse,".-The eldest complained of a burning sensation in the mouth and nausea; dryness of the throat and burning at the pit of the stomach; a, reddish mucus was discharged from the mouth. In an hour both were plunged into complete narcotism, with coma, convulsive movements of the eyes and the superior extremities, dilatation and insensibility of the pupils,55.-[1570.] A robust person took some bark of Mezereum for some ailment, and continuing the drug after the disappearance of his troubles, he soon complained of unbearable itching all over the body, so that he could not sleep one moment.

Even after leaving it off for thirty-six hours, he assured me that the itching still kept on increasing. A few grains of Camphor removed this itching,53.

Monotropa uniflora, L.

MONOTROPA.

Natural order, Ericaceæ.
Common name, Indian Pipe.

Authority. A. H. Y., Lafayette, Ind., Botanical Gazette, vol. iii, 1878, p. 37.

A young lady while examining the plant accidentally crushed the stem, and some of the juice was driven upon her lips. The mucous portions, which were somewhat chapped, became very much irritated, and began to inflame and swell considerably, while in two or three places upon the epidermal skin of the lip, small ulcerous sores were formed. The effect remained some four or five days, and then gradually healed. The whole appearance was very much like a mild case of poisoning with Rhus tox.

MORPHINUM.

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Authorities. 74, Le Cliniq. (Lond. Med. Gaz., vol. iii, 1829, p. 851), Mr. G. took 24 grains of the Acetate dissolved in 1 ounce distilled water; 75, M. Martin-Solon, Bull. de l'Acad. Roy. de Med., 1836, and Brit. and For. Med. Rev. (Am. Journ. of Med. Sci., 22, 1838, p. 202), effects of dipping the point of a lancet in an aqueous solution and inserting beneath the epidermis;† 76, same, effects of the Muriate experienced by Dr. Lafargue, from thirteen punctures on the front of the forearm; 77, Blanchard Fosgate, M.D., Amer. Journ. of Med. Sci., New Ser., 1, 1841, p. 112, for toothache took 1 ounce of a solution containing 14 grains of the Sulphate, after taking no food nor drink for eighteen hours; 78, omitted; 79, Lond. Med. Gaz. (Bost. Med. and Surg. Journ., vol. xxxiii, 1845, p. 128), a young woman, for scirrhus of uterus, vomiting, and pain in the stomach, applied to the epigastrium, from which the skin had been removed by a blister, grain of the Muriate; the same was repeated the next morning; 80, Chas. Foulke, M.D., Amer. Journ. Med. Sci., New Ser., 15, 1848, p. 568, Mrs. R., æt. sixteen years, eight months pregnant, for labor-pains, took 11 grains of the Sulphate in three hours; 81, C. S. S., Bost. Med. and Surg. Journ., 63, 1860, p. 325, a young man made habitual use of Morphine, generally taking one-fifth of a bottleful (1-8 ounces) in water; 82, J. S. L., ibid., p. 391, Mrs. A. H. S., æt. forty-two years, had taken Morphine for years; when first seen she was taking from 4 to 6 drachms per week; 83, B. Woodward, M.D., ibid., vol. lxv, p. 157, I took grain of the Sulphate at 7, 10, 1, and 4 o'clock. I repeated this experiment four times, at intervals of five days, with same effects; afterwards subjected five young men to same experiment, and with four obtained a very large increase and lower specific gravity of the urine; with one of them, on two trials, I found no perceptible increase or diminution of, but a marked lessening of, specific gravity; I did not obtain same results from Opium itself, but there was no difference whether the Muriate or Sulphate

From inoculation of all common preparations of Opium he saw the same effects, except that the papillæ sometimes acquired a diameter of an inch and a half, and then became radiated and diffuse.

were used; 84, Wm. Norris, M.D., Amer. Journ. Med. Sci., New Ser., 44, 1862, p. 395, a person, æt. nineteen years, took 75 grains of Sulphate in water; 85, Medical Circular, June 10th, 1863 (Brit. Journ. of Hom., 22, 348), effects of solution of Mor. mur., taken in the usual doses, but too frequently, for cold in the chest; 86, Dr. J. L. Prentiss, Chicago Med. Journ., December, 1866 (Amer. Journ. of Med. Sci., New Ser., 53, p. 565), a woman was said to have taken 5 grains of Morphia; 87, J. R. Wiest, M.D., Cincin. Journ. of Med., May, 1867, p. 265, Mr. W., æt. fifty years, took an unknown number of pills, each containing grain of the Sulphate; 88, Benj. B. Wilson, M.D., Med. and Surg. Reporter, vol. xix, 1868, p. 369, a woman who had been receiving hypodermic injections of grain of the Sulphate, now received a somewhat larger one; 89, J. J. Lyons, M.D., New Orleans Med. and Sur. Journ., vol. xxii, 1869, p. 292, a girl, æt. five years, took 5 grains of Sulphate to prevent the return of an intermittent, from which she had been suffering the previous week; 90, John Sprott, M.D., ibid., p. 506, for rheumatism, used daily for three years, from 2 to 4 grains of Sulphate; 91, C. H. Alden, Philad. Med. Times, vol. i, 1871, p. 295, L. R. took by enema between 12 and 15 grains of Sulphate, dissolved in 2 fluid ounces of water; 92, W. W. Grisson, M.D., St. Louis Med. and Surg. Journ., 1872, p. 353, a woman, æt. thirty-one years, took 6 grains of Morphine; 93, Geo. Bayles, M.D., Virginia Med. Rec., 1875, p. 188, Mr. S., for pleuritis of the right side, took within three hours and a half 50 minims of Squibb's solution of Morphia; 94, Dr. A. P. Hull, Philad. Med. Times, September, 1876, p. 581, a child, æt. six weeks, took grain of Sulphate; 95, E. H. Coover, Philad. Med. and Surg. Reporter, vol. xxxvi, 1877, p. 452, John H., æt. thirty years, for an abscess on the left parotid, took 2 powders, containing probably 24 grains of Sulphate, at an interval of twelve hours; 96, S. B. Chase, ibid., vol. xxxiv, p. 37, a man, æt. thirtyfive years, took 6 or 7 grains of Morphia.

Mind.-I found her, as she had been for some hours, crazy, with three or four holding her in bed; during the intervals of slight convulsions she was in this crazy condition,.-Subsequent to the commencement of the nausea, and previous to the exhibition of a gill of cold strong coffee, my mind was depressed, and considerable anxiety pervaded it, but it was at the same time restrained to a consideration of the condition of my system, and no pleasurable sensations had been experienced. The coffee, however, soon raised this weight of oppression, and, I may add, also the controlling power of reason, and in their stead, faucy in her wildest range roved on through scenes of rapture and splendor, which the mind of the patient, unassisted by such powerful influences, is utterly incapable of attaining. This delightful revelling of the imagination continued five or six hours, and during this interval my attendants, who spoke to me several times, could not determine whether I was asleep or not; neither can I settle the question myself, for, if asleep, I awoke so easily that the transition could not be perceived. But I am conscious that this state of mental delirium ended in a sound sleep, which was succeeded by a few hours of lassitude,”. -So nervous that the least movement in the room would make her spring from the bed,.-Sometimes talking in a partially incoherent, excited manner (after three hours),".-Incoherency in speech for three weeks,".-[680.] Mind much confused, but when persistently addressed, her attention was aroused, and she replied, though rather incoherently (after three hours); mind quite clear (fourth day),".-Lost his recollection (after six or seven minutes),".-Stupor,.-Stupor was fast approaching, but was not complete,

occasionally she would wake and fret (after three hours),.-Complete insensibility,, etc.-Comatose, although by persistent shaking and loud talking, he could be roused for a brief period,".

Head.-Dizziness,".-Slowly rolling her head (after three hours),.Pain in the head,".-Head felt very heavy (after three hours),".-[690.] Heaviness of the head,".

Eye.-Eyes sunken in the head,.-Eyelids half closed; conjunctivæ injected, pupils contracted to mere points; irides immovable (after three hours); pupils natural size or nearly so, and the irides movable (fourth day"-Pupil contracted (after three hours),, etc.-Pupils contracted to a pin's point,, etc.-Pupils contracted to a little more than a pin's point,. -Contracted pupil and complete insensibility,.-Great contraction of the pupils, almost perfect blindness,.-Saw every object double and very indistinctly (after three hours),".-She saw only one-half of surrounding objects; for instance, in the case of a person standing before her, she could see only the right or left half of the body; it was three weeks before vision was completely restored,".

Ear-1700.] Ringing in the ears,"9.

Face. Suffused and purple countenance,.-Complexion cyanotic,. -Countenance of a dark color,".-Face and lips livid,".-Constantly rubbing the nose, eyes, and face,.-Jaws rigid,".-Masseter muscles rigid (after six hours),86.

Mouth.-Teeth firmly closed (after six hours),.-Tongue dry and cracked in places,2-[710.] Clamminess of the mouth,".-The saliva of the mouth was being churned into a froth, which welled up and then disappeared at every return and subsidence of the respiratory movement,.Slow of speech, although if sharply questioned he would answer his name,". -It was with great difficulty that she could talk so as to be understood,8. Stomach. Thirst,.-Great nausea and many efforts to vomit (after five hours),".-Vomited at intervals (after three hours),".-Vomiting in the evening,.-The pain in her stomach recurred every few minutes, and became at times very intense; she made loud cries, ground her teeth, and threw her arms about violently; she described the pain as like that of cramp (after six hours); the pain became gradually less, and was felt more in the region of the umbilicus (after nine hours),".-It often produces a painful cramp of the stomach, and especially is it liable to do so in persons not in the habit of using it. This effect is readily relieved by a small quantity of some stimulant, brandy or spirits of camphor being the most effectual. One-eighth of a grain acts more powerfully on an empty stomach than half a grain after eating,99.

Urinary Organs.-[720.] Pain across the kidneys, followed by diuresis,.-Vesical tenesmus, but was unable to pass urine; about 8 or 10 fluid ounces removed by the catheter (after three hours); urine removed twice, about 12 fluid ounces each time (second day); passed urine naturally (third day),".-It acts almost invariably as a diuretic in from one to two hours,.-Passed 28 ounces of urine, with specific gravity of 1014, in twenty-four hours (before the experiment); measured all the urine passed at 9 P.M., and found it to be 48 ounces, very limpid, specific gravity 1003 (the day of the experiment),8.

Respiratory Organs.-When taken in a full dose it changes the voice, producing a temporary hoarseness,.- Respiration hurried,2. Breathing not more than once in forty-six seconds (after five hours and a half),".-The child breathed about once in fifty seconds for seven hours,.

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