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(soon after fifty minutes). Whenever I took the decoction of the bark of the root, or bark of the trunk, in the quantity of 3 ounces, it invariably had a purgative effect, which was very mild.

3 scruples of extract of the pith. But little alteration of the pulse.


Authorities. 15, Zeit. Ver. Hom. Ærz. (Est., vol. i, p. 429, a man, aged forty-six years, drank a swallow; 16, Darto-Massart, Gaz. Med. de Paris, Nov., 1836 (Am. Journ. Med. Sci., vol. xxi, p. 247), Mr. D., aged thirtyfive years, drank some instead of wine ; 17, Dr. Jackson, Bost. Med. and Surg. Journ., vol. Ixvii, 1862, p. 362, a man, aged seventy-two years, drank some, and at once took a large quantity of sweet oil, after four months he entered the hospital ; 18, John W. Ogle, M.D., St. George Hosp. Rep., vol. iii, 1868, Elizabeth G., aged forty-four years, swallowed a quantity of American potash ; 19, J. D. Norris, M.D., Maryland Med. Journ., a child, aged four years, swallowed a dessertspoonful of a solution.

Face.-Face pale, presenting the appearance of intense suffering (after a quarter of an hour),'6.

Mouth.-Tongue and back part of the mouth threw off a very thick and tough membrane (after two days),16 —Mouth and fauces very corroded; on introducing the stomach-pump, small shreds of softened membrane were found clinging to the tube when removed,"$. - On the following morning the mouth and fauces were in an extremely affected state. Everywhere the epidermal coating of the mucous membrane had been abraded, but still hung partly to it in large pieces, the mucous membrane itself was swollen and loose, the tongue was injected scarlet, the papillæ swollen, arch of the palate and the uvula extraordinarily swollen, the colors of these parts intensely dark red. In the mouth and fauces the patient had the sensation as if glowing coals were there, together with constant pressure to swallow and hawk up, which increased the pain; he discharged in a large quantity a secretion consisting partly of saliva, partly of mucus. The voice was hoarse and nasal, his disposition bounding on desperation. To these symptoms were added remarkable febrile symptoms (pulse 120) and unquenchable thirst,15.

Throat.- Ejection of mucous membrane of esophagus presenting perfect cylinder of tube," --Pain along course of esophagus,'.-Dysphagia from the first, and had lived mainly on a liquid farinaceous diet (after four months); probangs were used, and there was reported a stricture five and a half inches from the incisor teeth ; probang used till some weeks before his death, when he said he could swallow well enough without it,"".

Stomach.-(1540.] Nausea (soon),16 ---Regurgitation,"9 - Vomited immediately,"9:-Severe pains in the epigastric region (soon), 6. — Great pain in the region of the stomach and the course of the diaphragm,'s.

Stool.-Black stool followed the perspiration,'.

Fever.-General coldness (after a quarter of an hour), ".-Slight perspiration continued for two hours,



Celtis occidentalis, L. Natural order, Urticacea. Common name, Hackberry tree, Nettle tree. Preparation, Tincture of bark. Authority. 1, J. S. Wright, U. S. Med. Invest., New Series, 9, 1879, p. 339, proving with tincture made from bark; took ounce at 11 A.M. and 2 P.M., symptoms after second dose ; 2, ibid., a girl, whose ears were sore and swelled from piercing and wearing cheap rings in them, took 2 ounces in one day.

One hour after, cold and hot creeping all over the body; pulse quick and full; bones ache; flesh sore to pressure on chair-back, cannot sit on hard bench. Stretching of limbs; skin red and puffed ; blood vessels puffed ; thrilling sensation on the skin all over the body, as if pricked with the points of needles. Sharp pains through the lungs, sticking pain over the right eye. Sleep full of dreams of business ; next morning tired and weak, with headache; throat sore,':-Her face and body swelled. I gave Urtica capitata ; the next day the swelling had left the face and body, but her feet and ankles were swollen so that she could not wear shoes,


Cephalanthus occidentalis, L.
Natural order, Rubiaceae.
Common name, Button-bush.

Authority. E. D. Wright, M.D., Am. Hom. Obs., 1875, p. 177; took ounce tincture on two successive days.

Nervous, excited; felt light and easy, happy (first day).- Tootbache (second day).-Raw, sore throat (first day).—Bowels constipated (first day).

- Bowels loose, stool offensive; almost affected by the piles (second day). -Griping pains in the lungs (?); in body and limbs, especially in the joints (second day).-Joints of the fingers lame (second day).-Hard dreams about fighting, quarrelling; restless and tossing over second day).


Authorities. 23, Sharp's Essays on Medicine, tenth edition (1874), p. 790, proving of 1st dil

. (bo drop of sap of the plant); 24, Sharp, Month. Hom. Rev., vol. xx, 1876, p. 746, a man took 5 drops mother tincture (half sap and half spirit) at night; 24 a, same, afterwards took 10 drops at night.

Rumbling in the stomach (after half an hour), 24. - [1450.] Slight indigestion during the day,**. — Next morning less free evacuation than usual; and this continued the same for four days afterwards; the color darker than usual,” – Morning evacuations as usual in quantity, but rather darker (second day); no evacuation (third day); evacuation very small in quantity (fourth day),**.-On a healthy person its effect is to produce motions like those of a healthy baby; it increases the secretion of healthy bile,


Authorities. 2, P. T. T., Bost. Med. and Surg. Journ., vol. xlv, 1851, p. 373, poisoning of a child; 3, Mr. Wm. Smith, Pharm. Journ., Sec. Ser., vol. iv, 1862, p. 330, a man took about half an ounce ; 4, T. R. Brown, M.D., Maryland Med. Journ., November, 1878, p. 20, Mr. X., æt. thirtyone years, took about 11 ounces of wormseed oil, and 30 drops of turpentine, death in five days.

The symptoms were those of a narcotico-acrid poison, affecting the brain, spinal system, and stomach. He was insensible, convulsed, and foaming at the mouth; he, however, recovered under the use of emetics, combined with stimulants and demulcents. All remembrance of having taken the poison was completly wanting on recovery, — Deep, heavy, stertorous breathing, accompanied by a very peculiar rattle, as if there were a ball rolling loose in the trachea ; pulse small, weak, frequent, and feeble; eyes insensible to light, or even external objects; convulsive movements of the right half of the body; extremities cold ; any attempt at deglutition threatened instant suffocation,?:- Disagreeable eructations; nausea; staggering like a drunken man when walking; deafness to the sound of the voice, but exquisite sensitiveness to the sounds of passing vehicles ; he remarked as each vehicle rolled by that it sounded like the roaring of immense capnons right into his ear; also annoying buzzing in ears. His manner in smoking was peculiar. He would scarcely light the cigar before he would lay it down again, and take a fresh one, arguing clearly some perversion in taste. This was kept up until interdicted, and by the afternoon his mantel-piece was strewn with cigars only slightly used. Not the least disposition to engage in conversation. To one of his attendants he showed signs of distinct aphasia. He clearly wanted bin to get or do something for him, but could not make himself understood. His friend replied by writing, “ Don't understand,” at the same time handing him the paper and pencil with which to make known his wish. After holding them in his hand in a pensive state for some minutes, with a sort of flourish, he wrote in a perfectly distinct hand, “The paper mu,” waited awhile, and then with a painful expression of the realization of his difficulty, returned the materials and lay down. I.then repeated the attempt by asking him what medicine he had bought while away from home. After similar preliminaries as before he only managed to write two letters, " Th." In reply to my question as to how he felt, he responded, “I feel all right.” The latter, like the other words, were written in a perfectly distinct manner. During all this time his deafness, as described, was progressive, and became so pronounced as to make it impossible to talk to him. Still there was the same kind of sensitiveness to other sounds. For example, when the tea-bell rang, though he was in the third-story, three flights from where the sound came, he, without notice from members of his family, to their utter astonishment, got up and walked as deliberately as ever into the dining-room. He did not seem to know his accustomed seat, and sat at the wrong place. During the afternoon the aphasia was complete, so that he no longer found it possible to express his ideas to any one, which seemed to amuse him very much, as he laughed heartily. His bebavior all this time deserves comment. Whatever he did he would keep repeating it for a considerable time. When I entered the room he rose, shook me cordially and firmly by the hand, and then took his seat. In about a minute he arose, solemnly came forward and again shook bands with me, so that by twenty minutes he had shaken hands with me as many times. He then began to wash his hands, and though the basin contained no water, he went through the form of using soap and wiping with a towel as often as a dozen times in one hour. Many acts of similar import might be offered, some of which I observed and others were described by members of his family. I joined the patient at tea for the purpose of watching what up to this time had been to me an unsolved mystery. He appeared to relish his food, taking singly tea and bread. Towards the close of the meal, while grasping a fragment of bread, there was a distinct spasm of the right forearm and hand. His fingers were firmly clenched, and his hand forcibly flexed on the forearm. He was assisted to his room, his walk entirely natural, and when being placed on his bed he showed some resistance in striking at me. He at once commenced to groan, draw himself up, and tossed from side to side of the bed, suggesting abdominal distress. He soon became unconscious, and from his movements in bed it was clear that he was paralyzed in the right arm. This member was dragged helplessly after him, as my attention was first called to it by a looker on. The next day there continued impairment of motion and sensation of the right side, together with insensibility to touch of the right eyeball. During the third day there were frequent twitchings and stiffness of the right limbs, these culminated in a unilateral convulsion at daylight on the fourth day. At about noon of the third day he passed, as he continued to do to the end, except when drawn off, a large quantity of urine involuntarily in bed. In the afternoon the heavy breathing, with flopping of the cheeks, of apoplexy appeared. There was also more or less constant regurgitation of yellow frothy material from the mouth, which like the evacuation from his skin smelled of wormseed. The accumulation of this material would at times be so profuse as to embarrass respiration. During one of tbe attacks of dyspnea, and while in a drenching sweat, which suggested the approach of dissolution, he was gently turued in bed, immediately a general convulsion, markedly opisthotonic, appeared, lasting about two minutes, despite the use of chloroform. By this time a decided icterus appeared, which had been only noticed the day before. He died about five days from the beginning of his illness in a profound coma, and with a high temperature in his axilla,..


Authorities. (2 to 4, Essay by John S. Mitchell, Philada., 1803.) 2, W. M. Walmsley took 40 grains of fresh leaves of P. mac. at 10.30 A.M. (pulse 80); 3, Dr. A. Gregg, Jr., took 55 grains of same plant, with no effect; 4 grains of fresh leaves of P. umbel., after twenty minutes 20 grains more, pulse 70, at 1.30 P.M.; 3 a, same, took 25 grains at 11 A.M., pulse 72; 3b, same, took at 9 A.M. 30 grains, pulse 76; 4, Dr. Mitchell applied the bruised leaves of P. mac., wet occasionally with vinegar, to one arm, without result, as when given internally; at the same time applied P. umbel. in same way to the other arm; 5, H. P. Gatchell, Am. Hom. Obs., vol. xiii, New Ser., 3, 1876, p. 73, proving of P. rotund. ; 6, H. P. Gatchell, Am. Hom. Obs., vol. xiii

, New Ser., 3, 1876, p. 75, proving of P. mac.; 7, ibid., another proving

Mind.–Very nervous, cannot bear anything at all; hot, irritable, restless; thinks diseased state of the blood irritates the skin, as before the eruption of erysipelas, scarlet fever, or measles ; itches terribly,'.-Melancholy,':-Stupid and sleepy,":--Becomes partially unconscious, feels like fainting, as if brain paralyzed, mind gone,

Head. Some dizziness in the head (after seventy minutes),"".--Head heavy, feels as if he would fall down on it,'.—Wants the head pressed,':Slight headache (after forty minutes), -Headache, with pain in the bowels,'-[10.) Feeling of weight, as if in brain, along the brow,'.-Sharp pains and heat in interior of head, unfitting for exertion,'.-Pain in and above the forehead, '. - Dull heavy pain in the whole front and top of the head, Pain over right eye,

Eye.- At first eyes clear, now they burn; lids feel sore, ".
Nose,-Nose runs,".

Mouth.-Hollow teeth ache,':-Tongue feels stiff and thick in the middle, cannot raise it,'. —Mouth dry,".

Stomach.-[20.] Extreme guawing hunger,':--Slight nausea at the stomach (after fifteen minutes); nausea stationary after repeating the medicine (after twenty minutes),':- Feels drunk, and as if stomach burnt up with liquor, as if hard, dry, and tough, and as if rennet would be good for it, .- Burning in stomach,

Abdomen.-Sharp pain in right hypochondrium," :-Liver feels as if enlarged,'.-Bowels hard and swollen; thinks the glands are swollen ; bowels very painful, sore, and hard ; feels as if dropsy of abdomen,!:— As if bowels were sore and swollen on right side, .-Coliclike pains between the pubes and pavel,?. — Pain in bowels,'.— [30.] Uneasy sensations in his bowels (after one hundred minutes);}.

Stool.- After the colic pains a diarrhea, not very weakening,'.

Sexual Organs.-Aching in vagina, as if labia inflamed, : -Sensation of swelling in labia,®. -Stinging in labia, as if boils there,".-Excitement of sexual system,'.

Pulse.--In five minutes, pulse 80; ten, 80; fifteen, 80; twenty, 80; thirty, 79; thirty-five, 79; forty, 80; sixty, 80. No increase either in fulness or force,': --In five minutes, pulse 74; ten, 84; fifteen, 88 ; twenty, 75; twenty-five, 76 ; thirty, 79; thirty-five, 76 ; forty, 74; forty-five, 71; fifty, 71 ; fifty-five, 70; sixty, 65; sixty-five, 66; seventy, 69; seventyfive, 66 ; nivety, 64; one hundred and five, 64; one hundred and twenty, 60. Pulse somewhat weaker (after one hundred minutes), '.-In ten minutes, pulse 66; fifteen, 66 ; twenty, 64; twenty-five, 62; thirty, 62; forty, 60 ; fifty, 60; sixty, 62; seventy, 60; eighty, 57; ninety, 60. Pulse fuller (after ten minutes); weak (after seventy minutes),-.-In five minutes, pulse 76; ten, 76; fifteen, 78; twenty, 80; twenty-five, 80; thirty, 80; forty, 78; fifty, 76; sixty, 76; seventy, 72; eighty, 73; ninety, 72; one hundred and five, 76; one hundred and fifteen, 76. Pulse fuller and harder (after twenty minutes),3h.

Neck and Back.-[40.] Feels as if the neck were too small and tired,'.-Needlelike pains in the sacrum,?.

Extremities.--Limbs feel full, as if distended ; feeling like that from erysipelas,'.-Sensation of swelling in the arm-pits,e-Pain from armpit to scapulae, ".-Right arm as if paralyzed,!:—Pain in bones of forefinger,'. - Needlelike pains in the hip-bones," – Legs and arms weak,".

Generalities.-Seems to run all through the blood as a stimulant,".

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