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one plunges the head into a bath of Carbonic acid gas, there is immediately experienced heat, especially about the face and eyes. The gas getting into the nose causes prickling in the mucous membrane, sneezing, and profuse secretion of mucus, 97.—He experienced prickling in the eyes, vertigo, thundering in the ears, suffocation, the face became blue, purple, etc.,39 - Profuse lachrymation, heat of the face, rush of blood to the head,". -He inhaled the gas mixed in various proportions with atmospheric air. From 1 to 13 there was very little effect. 1 to 10 caused prickling in the limbs, and a sensation of constriction of the chest. 1 to 4 caused asphyxia and an increase of the pulse from 73 to 137, but it immediately fell to 98 on removing the gas,** --The secretions are in general increased, perspiration considerable, urinary secretion decidedly increased, and there were frequent efforts to urinate. Often the gas causes rush of blood to the hæmorrhoids, increased menstruation, epistaxis, and often hæmoptysis. In the organs of generation it causes great heat and excitement and turgescence. In women increased menstruation,".-Coma, red streaks running along the forearm in the course of the radial nerve, followed by swelling of the subcutaneous tissue, especially on the right side, and along the right supraorbital nerve. Subsequent development of herpes on the lips and on the forearm, and along the ischiatic nerve; development of bed-sore, After the poisoning there developed zona on the left side of the face, corresponding to the course of the trigeminus nerve,".



Authorities. 24 to 47, A. Delpech, Nouv. Recherches sur L'Intoxication Spéciale que determine le Sulfure de Carbone l'Industrie du Caoutchouc Soufflé, Paris, 1863, twenty-four new cases among workers in rubber factories ; 48, J. B. Tavera, Thèse de l'Intoxication par le Sulfure de Carbone, Paris, 1865, a woman worker in a rubber factory ; 49, same, case of a man ; 50 to 52, Gourdon, Thèse de l’Intoxication par le Sulfure de Carbove, Paris, 1867, effects on men; 53 to 55, Abel Marché, Thèse de l'Intoxication par le Sulfure de Carbone, Paris, 1876; (56 and 57, Berridge, Collection in Appendix in Brit. Journ. of Hom.); 56, Wutzer and Pellengham, Journ. de Chim. (Lancet, 1830-1 (2), 329), general effects ; 57, Dr. Geo. Kennison, Med. Times and Gaz., 1868 (2), 77, effects of external application ; 58, Dr. Davidson, ibid., 1878 (2), 350, W. G., æt. thirty-three years, took a quantity,

Mind.- Delirium, with incoherent talking," :-On two occasions he had nervous attacks analogous to hysteria ; the face was affected by convulsive movements, but he did not lose consciousness ; laughed involuntarily and irrepressibly,"- At one time during the night he seemed to be surrounded by enemies; persons were coming to harm him; he heard imaginary voices and saw strange objects ; this continued for four days, and he was taken to the hospital,- Hallucinations of vision and hearing, he seemed to see splendid spectacles of carriages, with magnificent objects, talked of the emperor, of money, and of grandeur, often incoherently,*. – Violent cerebral excitement, so that he had to be put into a straitjacket,%. It seems to bim as if he were constantly in a state of intoxication,”.-Beat his wife, **. -Violent and irascible, %. -- incessant desire to prattle and laugh without cause,”4. – [760.] Excessive gayety, followed by sadness and moroseness,50.-At first he was excessively gay, but with the progress of the poisoning he became extremely sad, and lost all energy, e.

-Exaggerated gayety, changing to profound sadness and absolute indiffer. ence, -Screaming, 4.-Extreme loquacity,46. — Excessive loquacity, but he cannot think of the words he wishes to use ; he searches in vain for an expression, and an attempt to speak results in stammering,. —The patient was sad, preoccupied, *2 : ---Preoccupation, with sad, melancholy ideas, indifferent to all about her," —When interrogated he replied by monosyllables or by signs with the hands; his intellect was greatly impaired, he sought solitude, and like a child was occupied by the objects immediately about him; when not amused he was inactive, seemed distrait,2.-Unable to fix the attention,.,- (770.] Oppression, 6. — Sad,“? - Profound sadness, ,25 31, etc.—Profound sadness, with irritable desire to weep,28. —His mood is completely changed; there is now profound sadness, with excessive impatience; at times absolute indifference gives place to the most violent anger, when he manifests great energy,%. — Wept with great facility, 46. Irritable, 28 37 43.--Great irritability,a.-Excessive irritability, intolerance of contradiction, 92 55. — Became exceedingly irritable and violent,* *6.—[780.] He became extremely irritable, violent, and intolerant of contradiction, -His character cbanged entirely, at first he became irritable, afterward sombre and sad,". — Complete indifference,". — Memory profoundly impaired,27 29:—This man, usually intellectual, bas now lost all desire for study; his imaginatiou is wholly occupied with the most absurd reveries, ". - Unable to find words to express his thoughts,"h: - Incoherence of ideas, *. Loss of memory,2 24, etc.-Progressive loss of memory, 25 4. - Weak memory, especially for recent events," – [790.] Loss of memory, with difficulty in expressing ideas, -His memory became defective, and he found it very difficult to formulate his ideas, or express them by words,"9.-Complete loss of memory,"1 34 --Stupid ; cannot fix his thoughts upon any object, cannot express his thoughts," --Loss of consciousness, lasting several minutes, 4 —On two occasions the patient fell suddenly with loss of consciousness,“9:—One day he fell down, lost consciousness, had an epileptic attack, followed by paralysis of the limbs,38 —Complete loss of consciousness at one time,“

Head.-Vertigo, 2*, etc.-Intense vertigo," *-[800.) Frequent intense vertigo," - Attacks of vertigo, so that he could scarcely stand, with partial loss of consciousness,". -Sudden vertigo, during which he nearly fell to the ground, and had to be taken home,. -Intense vertigo, with loss of smell; vision was affected in that all objects seem larger than they really are," — Violeot vertigo, reeling so that he was obliged to stop at almost every step, 4. —Heaviness of the head," —Headache," ", etc.-Intense beadache, 28 57, etc.—Most intense headache, with a sensation of painful pressure in the temples (first day),36 - Violent headache, with distressing throbbing at the temples, aggravated towards evening,"?. —[810.) Violent intense headache, characterized by compressing pain from one temple to the other, associated with vertigo and great agitation," -Constrictive headache,'.—Compressing headache,”". —Headache like the painful pressure of a tight cap,32. — Very intense compressible headache, especially in the root of the nose, and in the temples; it consisted of a sensation of most violent constriction in the temples, without throbbing; it was associated with extreme stiffness of the neck; this painful stiffness, especially over the posterior portion of the neck, was accompanied by a local sensation of very great coldness; the patient experienced great pain in turning the head; the pain in the neck was associated with very distressing ver

tigo,38: -Sensation as if a band of iron were compressing the head,”: – Violent intermittent pain in the head and frontal region,-Lancinating pain in the head," - Intense fruntal headache, 25 - Violent frontal headache, especially in the evening, with vertigo and ringing in the ears,5%. [820.] Temporal headache, 37 41 -Compressing headache through the temples," – Violent compressive headache through the temples, aggravated by walking, so that each step caused a violent, painful shock in the head," Intense compressive headache, occupying the temples and occiput," — Violent pain in the right side of the head,

Eye.- At one time was seized with violent inflammation of the right eye, kerato-iritis, treated by Calomel and Atropia, ".--Eyes fixed, without expression ; pupils dilated, especially the left, but very sluggish ; the patient, however, could not see with the right eye as with the left; the ophthalmoscope showed in the former very slender retinal veins, extravasations of blood into the vitreous, extremely fine filaments and points floating in the vitreous,".-Ophthalmoscopic examination showed the papillae very pale and deeply excavated, after several months,"?- Progressive atrophy of the ophthalmic papillae of the left eye," :-Pupils mobile, moderately dilated; the field of vision normal; ophthalmoscopic examination revealed a slight paleness of the internal segment of the optic nerve of both sides; there was marked excavation of the papillæ, which were less transparent than normal; the optic nerve had the appearance of a smoked glass, 27.[830.] Pupils sluggish, rather dilated. Ophthalmoscopic examination of the fundus of the eye showed depigmentation and some dilatation of the retinal veins, 6. — Pupil incompletely dilated (he had lost his right eye by getting a drop of the vulcanizing mixture into it, followed by intense pain and ophthalnia, and formation of a staphyloma of the cornea and iris),". -Sensation of heat and pricking in the eyes,s".—Marked anæsthesia of the cornea, which was insensible to pricking with a pin,52-Marked anesthesia of the cornea," - Lids. Lids affected by spasmodic trembling, s. Pupil. Pupils dilated, Vision. Vision at first very clear,47 Great susceptibility to light,“ — Dimness of vision,"9.—[840.] Mist before

193 49 50 – Vision dim, as through a veil," : — Vision dim, as though objects were enveloped in a mist,". - Amblyopia ; all objects seem covered with a mist,“?.—Reading was impossible, for though the left eye distinguished objects, the right seemed covered with a mist,". – Vision became dim. Permanent and progressive alteration of vision; pupils contracted, ipsensible, sensitive to Belladonna; the ophthalmoscope showed that the optic was congested," – Vision became remarkably affected; there was diminished clearness of objects, which seemed enveloped in mist; on attempting to read the letters moved and trembled; the use of a glass was of no avail,"7.–Vision is distinct for a limited distance, but beyond that everything is enveloped in a mist,% –Vision impaired, so that it was difficult to distinguish objects,4 – Vision became disturbed ; a portion of the field of vision was obscured, so that he no longer saw the concluding letters, 29. — [850.) Vision teeble, was unable to read the names of the streets," -- Vision impaired; all objects seemed to tremble,55 – Tremulous vision ; all objects seen enveloped in mist,25:-Difficulty in fixing the vision upon any object,28 — Loss of vision of the right eye, ". - Vision completely lost," Double vision, 52 50

Ear:-Very paivful pricking in the external meatus auditorius, 54 Impaired hearing, 26 47 19—Hearing very much impaired; it seems as though something were stuffed into the ears,". - [860.] Hearing in the left ear

26 50 51

the eyes,

entirely lost,so. - Ringing in the ears," - Insupportable tinkling in the ears, 2.

Nose.-Profuse bleeding of the nose at times,".—Pain in the nasal fossa, as though he had inhaled Sulphuric acid, ".-Impaired smell, ** 50.

Face.-At one time his face became very red, but soon afterwards was very pale,53 - He has the aspect of astonishment, with hesitating speech and loss of memory,**. – Countenance expressive of the most profound sadness, 6. — Convulsive movements of the lips,5? — [870.] The lips were stiff

Mouth.--Stiffness of the tongue,".—Complete paralysis of the tongue,". -Salivation," -Constant desire to spit,-Constant salivation, * -Salivation, with constant desire to spit, 2. —Constant spitting on account of excessive secretion of saliva," : – Taste impaired,so

: - Difficult speech,** *—[880.] Speech became embarrassed,? - It was with difficulty that he could articulate his words, it seemed difficult to move the tongue, 26 41.- Extreme difficulty in expressing his ideas, the patient said his tongue would not work,".

- Experienced great difficulty in articulating words, because he could not move his tongu"; the tongue seemed rigid and awkward, causing a kind of stammering, $ - Loss of power of expressing his ideas; his tongue seemed to refuse its office, 9.

Stomach.- Increased appetite, *. - Appetite increased, digestion difficult, irregular, with colic, vomiting, and congestion,'.- Enormous and iosatiable appetite,".--Appetite ravenous,".- Enormous appetite and voracious eating," — [890.] Ravenous appetite; the patient said he could eat all day long, 5 - Marked diminution of appetite, 931 - Appetite very irregular,** Complete loss of appetite," - Anorexia without vomiting,*. -Great thirst,*2 -Great desire to drink,M.-Constant nausea, 4.-Nausea without vomiting, 30 36 — 900.) Vomiting," - Vomiting of food and glairy mucus, Violent vomiting at once on taking food," -Acute pains in the stomach," -Frequent cramps in the stomach,95.

Abilomen. – Fetid flatus," – Profuse fetid intestinal flatus, Colic, 12. —Frequent colie," - Violent colic,918-1910.) Violent colic and diarrhea for three months, *. --Very acute pain in the groin,**.

Stool.-Profuse diarrhoea, ".-Fetid diarrhea, ".- Constant fetid diarrhea," --Diarrhea with colic," -Frequent diarrhea, with sensation of smarting in the anus, 29.- Alternations of constipation and diarrhea, Intense constipation," "1.

Urinary Organs.-Intense pain in the kidneys, -[920.] Violent cutting in the urethra during micturition, s. — Tenesmus of the bladder and frequent urgent efforts to urinate, and emission of two or three drops at a time,“: -Micturition slow and painful, 59 — Micturition, associated with cutting pain in the urethra," —Micturition painful, accompanied by acute burning pain,*-Micturition excessively painful, with tenesmus and frequent desire to urinate; urine bloody,"h: ---Sinarting during micturition," Frequent efforts to urinate; the urine was passed guttatim, accompanied by burning in the urethra, and tenesmus of the neck of the bladder, Urine highly colored, ** -Urine turbid, 6. —[930.] Urine pale and turbid, **.

-Urine slightly albuminous, very red and turbid, 50 -Urine red, containing an abundance of carbonate and phosphate of lime,

Sexual Organs.-Erections difficult, the patient says “ he reaches no result in five times, '55. — The testicles are very small," —Diminished size of the testicles, with diminished sensation on pressure, ** — Testicles not painful to pressure, ".-Sexual excitement, 25 38 63.-Excessive sexual excite

2131 +


25 31

ment,2447,- Excessive sexual excitement, constant fatiguing erections giving place speedily to complete impotency,*-:-[940.] Sexual excitement sometimes amounting to the greatest intensity; at night in particular, he was often taken with veritable rage, during which he had coition with real fury," --Sexual excitement at first, followed after a time by complete loss of power; two or three times his wife became pregnant, but miscarried, ". -He became very amorous; erections, however, were seldom, coition much too long, and ejaculation short and incomplete, 36 — The sexual appetite at first increased, but afterwards diminished, until there was complete absence of desire ; at times an incomplete erection resulted in indefinite coition without emission; or at times an ejaculation was obtained with great difficulty, but was very profuse, 7.-Sexual excitement, with loss of power,99. -Sexual excitement after a time gave place to complete indifference, etc.- At first sexual instincts were very much excited, but afterwards they disappeared, and at last there was complete impotency, 36. —Complete loss of sexual power,36 41 19:—Sensation as though the genital organs were completely chilled,36 –Symptoms of uterine catarrh, 16 — [950.) Profuse menstruation,".—Menses arrested ; at the same time she became very large, and had the appearance of being pregnant; after a while she was seized with violent hæmorrhage, which lasted six months, and was only arrested by the use of ergotin,9*. -All sexual sensation entirely disappeared; there was complete indifference to her husband, 35.

Respiratory Organs. – Voice feeble," – Deep bass voice, a. During the last two months the sounds of his voice became altered in tone,4. –Tormenting cough and irritation of the bronchi,99. —Breath fetid,3*. -Very great difficulty of respiration on ascending stairs, * -Prolonged expiration,“–[960.] The form of the chest was not at all altered, but expiration was more prolonged than normal, 6. —Constant depression of breath,%7.-Gets out of breath easily,s".

Chest.-Auscultation of the lungs showed prolonged expiration over the posterior portion, 26. —Some emphysema of the lungs,".

Heart and Pulse.—The murmur of the first sound of the heart extended along the great vessels,“? — The volume of the heart was normal, but with the first sound there was a prolonged murniur, which extended along the vessels of the neck,** -Slight murmur of the first sound of the heart,". I-Anamic murmur of the heart, : -Anæmnic murmur in the large vessels," -[970.] It excites powerfully the activity of the heart and arterial system. Its internal use causes acceleration of the pulse, increased heat, and sanguineous congestion towards the skin and genito-urinary organs. The next remarkable secondary symptoms are abundant diaphoresis, increase of the urinary secretion and of the menstrual discharge, Palpitation,“:— Violent palpitation,50. —Pulse moderately accelerated, 34. Pulse feeble, compressible,

Neck and Back.- Pain and tension in the nape of the neck, fol. lowed by development of anthrax, which made rapid progress, was arrested by crucial incision, followed by extremely profuse suppuratiou; this was followed by improvement and complete cure of the paralysis and general condition,"? - Pains in the back,54 - Pains in the loins, 36.

Extremities.—Trembling of the limbs, 31 32 50. —Trembling of all the † Miscarriages are frequent among the women who work in rubber factories. I A short time afterwards the patient died from the rupture of a small aneurism of the aorta.

VOL. X.-29



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