Billeder på siden
PDF
ePub

experiment,.-Sensation of dulness in the head like pressure,.—[490.] Tension in the head,".-Pains on the top of the head,".-Compression of the temples,".

22

Eye.-Eyes injected, 25.-Eyes injected and very brilliant,".-Heat and prickling in the external angles of the eyes,".-Suffused eyes,20.— Pupils dilated,-Pupils greatly dilated,".-Pupils dilated, sensitive to light,".-[500.] On attempting to write, I found that the characters made with the pen were exceedingly fine,".-Sense of a flame playing in front of the eyes,.

Ear.-Loud singing in the ears,27.

[ocr errors]

Face. Became very pale, and fell down prostrated,".- Flushed face,20 26-Stupid expression,".-Grimaces, as in chorea,".- Efforts to laugh, Contractions of the muscles of the face,.-Spasmodic contraction of the jaws,".

Mouth.-[510.] Mouth dry,".-Mouth and throat dry,26.

Throat.-Dryness of the pharynx,".-Swallowing became difficult on account of absence of saliva; it was impossible to eat,".

Stomach.-Ate with unusual avidity, in fact, like a glutton; after the meal she had an appearance of astonishment, and looked at persons about her with a strange expression,".-Nausea,".-At last nausea and profuse vomiting,.-Heaviness in the epigastrium,”.

Urinary Organs.-Frequent efforts to urinate,".-Difficult, profuse micturition,27.

Respiratory Organs.—[520] As the too frequent employment of this plant must induce considerable bronchial irritation, with repeated attacks of pulmonary congestion and inflammation, emaciation as a necessary sequence gradually ensues, while a premature decrepitude of frame, conjoined with serious organic affections of the lungs, insidiously steals onward, and under the mask of phthisis finally terminates the existence of the victim,.-Violent paroxysms of coughing,.-Respiration rapid, 7. -Respiration very difficult,".-I breathed with great force, with a sensation of heat,".-Dyspnoea,.

21

Heart and Pulse.-Palpitation, 2.-Pulse rapid,".-The pulse became very rapid and small,".-Pulse very rapid and irregular,".-[530.] Pulse 75 (before the experiment); rose to 140, and became very irregular, -Pulse 80 (before the experiment); rose to 140, and then varied from 130 to 140 for some time,".-Pulse 120,2.--Pulse 100,".-Pulse small and irregular,2.

Neck and Back.-Beating in the nape of the neck,".-Pains at the base of the cerebral column, extending along the sciatic nerve, and in the hip-joint,".

Extremities.-Contractions of the limbs, as in chorea,".-Stiffness of the limbs,".-Heaviness of the limbs,".

Generalities.-[540.] When walking, seemed affected with chorea,". -General stiffness,".-Tendency to immobility,".-Great feebleness after the experiment,21 26 27-Great fatigue,".-Great lassitude,".-After the experiment great feebleness and desire to sleep.25.-Sensation of indolence in the whole body,".-Frequent remissions, during which I said the attack had passed off, but I had no sooner said it than the attack returned anew,21.

Skin.-Vague sensation of tingling, like a beginning of anaesthesia of the skin (after half an hour),".

Ferer.-[550.] Extremities cold,26 27.-Sensation of great heat,25.Heat of the skin,".-Heat of the head,".

CANTHARIS.

Authorities. 113, J. M. Fontanelle (Rev. Med.), Lancet, vol. ix, 1826, p. 233, a man, aged twenty years, took ounce; 114 (Midland Reporter, No. 11), Bost. Med. and Surg. Journ., vol. v, 1831, p. 75, two young men took some lytta in raspberry brandy; 115, W. Miller, Lancet, 1834-5 (2), p. 114, a woman, aged twenty-five years, swallowed some blistering plaster; 116, Med. Gaz., March 26, 1836, three negroes took some tincture; 117, G. Smith, Lancet, 1840 (1), p. 733, a woman, aged sixty years, took a piece of blister plaster about the size of a walnut; 118, Brit. Journ. of Hom., vol. iv, 1846, F. T., aged seventeen years, was engaged all day in making "Emplastrum Cantharidis;" 119, Dr. C. H. Hildreth, Bost. Med. and Surg. Journ., vol. lii, 1855, p. 80, a man took a quantity of powdered Canth. in gin; 120, W. R. Spence Jeffries, Brit. Med. Journ., 1876 (1), p. 190, a lunatic took 3 fluid ounces of tincture; 121, J. M. Schley, M.D., . Hahn. Month., 1878, p. 641, Mr. J., aged twenty years, took 2 drachms made into a fly-blister, at 5.30 P.M., during treatment Camph., Can. sat., Ars. and Ipecac. were given; 122, M. Rosolino Braga, Med. de Rio de Janeiro (Lond. Med. Rec., 1879, p. 80), M. C., aged twenty-three years,

drank Canth. in wine.

Head.-Headache and dull heavy feeling around eyes (second day),11. -Shooting darting pain in right temple and in right eye (third day),"

Eye.-Great dimness of sight, attended with smarting and burning round the eyelids, and round the balls of the eyes; constant lachrymation; the eyes turned towards the nose; twitching of the eyelids; he could not close his eyes without great pain, from smarting of the lids chiefly; there was considerable redness, and an apparent distress from the inflammation of both eyes. Some drops of the strong Camphor tincture were given him. The next morning everything appeared yellow. The nose was also considerably affected; some swelling with redness and heat, within as well as without, with the appearance of suffering from severe coryza," ,118.

Face.-Face flushed (second day),2.

Mouth.--Tongue coated white down centre (third day),121.

Stomach, Abdomen, and Urinary Organs.-Poor appetite (third day),-Great thirst, and throat very dry (second day),".-Nausea after eating (fifth day),[1660.] About 11 P.M. (after six hours) commenced to vomit, which, however, produced little pain, as the contents of the stomach came up easily. At 2 P.M. the greatest pain was produced by incessant vomiting and nausea. His retching was painful to look at, for after the most violent efforts he would bring up at most some of the administered medicine or a little mucus, but no bile at any time,-In an hour or two, vomiting and strangury commenced; the urine discharged being scanty in quantity, and contained blood. On the third day, she was attacked with severe pain in the region of the left kidney, accompanied by tenderness on pressure, and sympathetic fever,".-Vomiting, with severe pain in the lower part of the abdomen, accompanied with bearing down, and most intolerable inclination to micturition, with heat and smarting so acute as to cause her to scream; also severe tenesmus, without evacuation of the bowels,-Gnawing painful feeling over region of stomach, extend

116

ing into back between shoulders (second day),12.-Violent pain in the stomach, bowels, kidneys, and bladder; a constant desire to make water; and a burning heat in the throat,".-Soon complained of lancinating pains of the stomach, burning of the throat, and great nausea. In two hours, violent retching succeeded, and the vomited matters were streaked with blood; they consisted, however, chiefly of frothy mucus. Next morning the pains continued, accompanied with cold clammy sweats, difficulty of swallowing, and in the evening, salivation. The mucus expectorated was of a pink color. Strangury supervened and continued for six days,' Flatulency, which when belched up gave temporary relief (first day),12, Rumbling in the bowels (first day),".-Severe pain in the lower part of the abdomen, thence extending into the lumbar region, but most intense just above the pubis. Some nausea, but no pain in the stomach,"9. 9.- About midnight he was seized with strong desire to urinate. In spite of all his efforts he could pass only a few drops of scalding urine, attended with severe pain throughout the length of the urethra, especially at the meatus, where he had a sensation like that of the pricking of pins. These symptoms became worse, and they were attended with priapism and severe pain in the genito-urinary organs, as well as in the lumbar region, and with intense thirst. At 9 A.M., he was much agitated, crying out and very restless. The eyes were injected and lustrous, the pupils dilated, and the countenance animated. The pulse was small and frequent. There was nausea with intense thirst. There was the most acute pain in the urethra, rendered much worse when with great difficulty some drops of urine were expelled. The desire to micturate was incessant, and an acute state of nervous erethism was produced. Only a very small quantity of urine could be discharged; and this was thick and bloody. The abdomen was retracted and sensitive to pressure, especially in the hypogastric region, where the slightest touch produced acute pain. Pain was also felt in the lumbar region, owing to the kidneys being affected, and this pain extended downwards to the perinæum. The catheter brought away a small quantity of thick bloody urine, containing albumen in marked proportion, [1670.] He went to dinner at 6 P.M. (after half an hour), but had little or no appetite, and about 8.30 went to his room suffering much pain in his abdomen and in the region of the bladder. The first and most prominent symptom was an excruciating burning before passing water, which was increased as the water left the bladder. About 9 he commenced to have the most excruciating pain in his bladder, with the continual desire to pass his water, which could only be pressed out in drops, but often bloody, and sometimes small clots would pass through the urethra, producing so much. agony that he came near fainting on several occasions. About the same time his bowels moved several times, the passage being loose and without pain, except as the last fæces passed from the rectum, when he would experience some pain and straining, which soon extended to the bladder, bringing on the most painful tenesmus, which was but little relieved when one or two drops of bloody urine passed. At 2 A.M. he complained mostly of a tearing-boring pain immediately over the region of the right kidney; it was painful for him to lie in any position, but when his back was bent in, he felt more comfortable. At times he said the pain was most acute, and he would groan fearfully under the agony; this would last for several moments, when a short period of comparative ease would ensue, only to be succeeded by the old pain. This acute pain did not remain entirely localized to the region of the kidney, but followed the direction of the

122

ureters. The desire to urinate was somewhat better, still every ten or fifteen minutes he would seize the chamber, and under the greatest agony pass sometimes one-half ounce of urine without any appreciable appearance of blood, when probably the next time he would pass urine the first drop seemed to be almost pure blood. It was as the last drops passed the sphincter vesica that the pain amounted to torture, and though a young man of courage, his self-possession would forsake him, and his face betrayed what his sufferings were,.-Burning feeling in and near orifice of urethra when passing water, and occasionally also when perfectly quiet; in the morning noticed the parts were slightly glued together (fourth day),"-The amount of urine passed this morning was four ounces; its color when held up to the light was a reddish brown, showing the presence of a small amount of blood. Neutral on test. On adding Nit. ac., also when heated, albumen was precipitated in abundance, amounting perhaps to per cent. The presence of albumen was found to be caused by the large quantity of blood in the urine. Under the microscope a very large number of blood-corpuscles, occasionally pus-corpuscles, epithelia of bladder, and spheroidal cells from the tubuli uriniferi and pelvis of kidney were to be found. The epithelia from the bladder were more numerous than those from the kidney. There was some mucus, with which the blood-corpuscles seemed to be intimately mixed. There were no crystals, no casts. The deposit at the bottom of the vessel, after standing some little time, was considerable (first day). Urine pale yellow. Reaction alkaline. Albumen present, but in less quantity. Under the microscope there was a diminution of the bloodcorpuscles, and epithelia from the bladder. The cells from the pelvis and kidney had diminished some in number (third day). Urine light yellow, much deposit, reaction alkaline. Albumen much decreased. Microscope shows a marked diminution of blood-corpuscles, a diminished number of cells from kidney and epithelia of bladder. On the other hand there was much mucus, intermixed with large quantities of urates, and some crystals of carbonate of ammonia (fifth day). Urine alkaline; no albumen; no blood corpuscles. Increase of mucus, urates, and epithelia of bladder, and an exceptional cell from kidney (eighth day). Urine alkaline, much sediment. Large quantities of mucus, with epithelia of bladder, and an exceptional cell from pelvis of kidney (thirteenth day). Urine varied frequently in appearance now, sometimes being quite clear; this was more marked toward morning, whereas towards noon it would be quite cloudy. Color of urine passed in office decidedly more natural. Alkaline, large quantities of mucus, urates, epithelia from bladder, and crystals of carbonate of ammonia (nineteenth day),121.

Heart and Pulse.-Pulse accelerated, 92; skin hot (after nine days),

121

Generalities.-Nervous, constantly threw himself about in bed, and could not sleep (second day),2.-After two hours and a half she was suf fering much from burning pain and constriction in the throat; her eyeballs were prominent; her lips and mouth were parched and bleached (blistered). She was salivating, retching, and vomiting a glairy tenacious mucus; her tongue was also bleached along the sides and tip; but was blackish brown in the centre, and much swollen. The breathing was very irregular and imperfect, sometimes quick, sometimes slow, and at great intervals. The pulse at the wrist was full and bounding; the vessels of the head and neck were much congested. The poor creature appeared to be suffering great agony, as was indicated by her expression of countenance, and the throw

ing about of her arms and body in her endeavors to obtain relief. Vomiting was free, and the patient complained much of pain in the gullet, and great difficulty in swallowing. Seven hours after the poisoning she complained of pain over the bladder, uterus, and kidneys, especially severe over the hypogastrium. She passed a restless night; she frequently tried to urinate, but ineffectually, only passing a little blood instead of urine. The bowels acted slightly, the motion being black and tarry-looking. The pulse was now small and compressible; she died in twenty-one hours and a half after the poisoning. The post-mortem showed in the posterior and upper surface of the stomach, three inches from the pyloric end, a perforation sufficiently large for a small hen's egg to pass through; the edges of the perforation were ragged, congested, and blackened, and the mucous membrane for two inches on each side was congested and blackened, and the mucous surface of the stomach and lower end of the gullet generally in a blackened and softened state, and coated with a black grumous matter,12 -Almost immediately seized with violent heat of the urine, heat in the throat, and pain in the head. These symptoms increased, and were followed by excessive sickness. Eight hours after the accident he passed a quantity of blood from the urethra, with excessive pain,113.

Skin.-Brownish-yellowish appearance of skin (fifth day),111.

CAPSICUM.

120

Authority. 12, Dr. Högyes, Archiv. für Exper. Path. und Pharm., 9, 122, five hours after dinner I took in a capsule 0.1 cc.

In about ten minutes I experienced eructations, which at first were odorless, afterwards had a taste of pepper. At the same time there was a slight but not disagreeable sensation of warmth in the stomach, which extended through the esophagus to the fauces, followed by frequent eructations, sensation of warmth amounting to slight heartburn, after which the eructations became burning. Later there were rumbling and flatus in the bowels. After an hour the symptoms disappeared, the sensation of warmth in the epigastric region ceased. The next morning I had a rather soft stool which glimmered slightly, followed for a short time by burning warmth in the anus. An assistant took 0.2 cc. He experienced the same sensation of warmth in the epigastrium, finally becoming a violent burning, followed by inclination to vomit, and general sick feeling. After half an hour, violent rumbling in the bowels, with inclination to stool, relieved by emission of flatus,12.

CARBO VEGETABILIS.

Authorities. 5, G. Nelson Smith, M.D., Am. Journ. of Hom. Mat. Med., vol. v, New Ser., 1876, p. 183, Mrs. Dr. J. L. C. began with eating bits of charcoal for "heartburn," and to "sweeten the stomach," but latterly she had been in the habit of triturating it to an impalpable powder, and taking about one half of a teaspoonful two or three times a day; (6 to 25, Conrad Wesselhoeft, M.D., Trans. Am. Inst. of Hom., 1877, p. 119); 6, E. E. Holman took eight doses of 3d trit. in one day; 7, L. W. Todd took one dose of 34 trit.; 8, Mrs. F. H. Stanford took repeated grain doses of 1st trit. for six days; 9, same, took repeated doses of 2d trit. for nineteen days; 10, R. R. Trotter took repeated doses of 1st trit. for twelve days;

« ForrigeFortsæt »