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cine affected the bladder only through the increased secretion of urine (fourteenth day),'.

Sexual Organs.-Diminution of the sexual desire since the commencement of this proving (tenth day),'.-Diminution of the aphrodisiac sense still continues, and the whole function seems so weak as to be wellnigh removed, and has been since the second day of the proving. The excitement reaches a low pitch, at which it culminates from a slight cause, assimilating impotency (sixteenth day),'.

Respiratory Organs.-Dry hacking cough of a few minutes' duration, at 3 P.M. (seventh day),.-Hacking cough and fluent coryza with the chill (tenth day),.-Involuntary sighing at times, for the last three days (eleventh day),.-Inclination to sigh continues, and is still marked; I find myself making frequent involuntary inspirations; this has been for a number of days (sixteenth day),'.

Chest.-Dull pain in a small spot in right chest, near mammary gland, at 5 P.M., lasting half an hour (seventh day),.-Considerable pain in right chest when pressed upon; some, but less in the left chest (ninth day),.— A sharp pain about the sixth rib of the right chest, a little to the right of the mamma, worse on inspiration, lasting ten minutes; 5 P.M., a like pain at a corresponding part of the left chest (ninth day),'.-[720.] The pains above described in the chest felt very often through the day (tenth day),. -Sharp pain for a short time in the region of the heart (8 P.M.), (tenth day),.-The sharp pain in the left chest, about the seventh rib, and to the left of the mamma, followed by a dull pain, felt more when inspiring deeply, and this still continues (8 P.M.), (tenth day),'.-Pain in the region of the heart, violent at times (eleventh day),.-Sharp pain in the region of the heart, when making an inspiration; most marked when taking a deep inspiration (eleventh day),.-Sharp pain between the fourth and fifth ribs of the left chest, a little to the left of the heart, occurring frequently during the forenoon; so sharp and severe as to cut off the breath at times. The sharp pain would last ten or fifteen minutes, leaving a soreness for a longer or shorter time, and then come on again. The pain in the left chest has been troublesome through the afternoon; felt most during a deep inspiration, though not all the time present. Sharp pain in the right chest by turns during the same time (eleventh day),.-Pain in the chest troublesome, though not constant through the day (thirteenth day),'.-The pains and soreness still felt about the chest, though not as constantly as several days ago (fourteenth day),.-A sharp pain as though some round sharp instrument was pushing out the lower end of the sternum, for a short time, at about 12 M. (sixteenth day),.-Pains in the chest still troublesome, passing from place to place; it is felt in the central part of the left chest in front, and passed thence under the left scapula, but is of a less acute character, but more and more aching. Pains still aggravated by a deep inspiration (sixteenth day),'.-[730.] Before rising in morning, sudden sharp cuttings or stitckes in region of heart, continuing about five minutes, and then going off. Slight pain of the same nature, preventing a full breath, occasionally during the day (eighth day),".

Neck and Back.-Crampy pain in nape of the neck, first on one side and then on the other, lasting for a short time (thirteenth day),.Sharp pain under the left scapula, towards the spine, at 9 A.M., continuing ten minutes, followed by dull pain in the shoulder-joint (second day),'.— Pain, with soreness, under the left scapula (thirteenth day),.-The latter part of the night, and in the morning, dull, or pain as if from a bruise,

on each side of dorsal spine (fifth day),.-Pain on each side of dorsal and lumbar spine, as from a bruise, when awakening, on the following morning, disappeared after exercise (eighth day),.-The soreness of the muscles of the back continues on getting up in the morning (tenth day),'.-Sharp pain in region of lumbar vertebrae, and top of sacrum, lasting a short time, followed by soreness (eleventh day),'.

Extremities.-During forenoon, pain in all the limbs, worse in gastrocnemii, as from a cold (second day),".

Superior Extremities.-Aching in the right arm, in the left temple, and shoulder-joint, lasting for a short time (second day),.—[740.] Dull pain in the left arm below the elbow and wrist (ninth day),.-At 11.30 A.M., pain in the right arm, from the elbow to the hand, with lameness of the wrist, all lasting till 9 P.M. (tenth day),'.-Pain in right wrist, with lameness as if bruised, at 7 A.M., lasting half an hour (third day),'.— Tremulous motion of the hands (eighth day),'.-Aching in pulp of left forefinger, sometimes extending up the arm, and giving it a sensation of weakness (continually all day), (eleventh day),".-Pain in left forefinger to-day, as yesterday; felt more when driving (twelfth day),.

Inferior Extremities.--Severe lame or bruised feeling in both nates (tenth day),.-Pain in nates better (eleventh day),.-Biting stinging in small spot on left nates (second day),".-Shooting through the left thigh (eighth day),-[750.] Sharp pain in the tendons of the inner hamstrings, when walking, lasting twenty minutes, at 6 P.M. (ninth day),!— Aching in outer side of right knee in bed, soon followed by aching in ball of left foot, relieved by motion, lasting about ten minutes (ninth day),".Drawing pains in gastrocnemii (third day),.—Slight jerking pain in the right knee-joint,.-Weakness of legs, especially below knees, as if from severe labor (second day),.-Dull pain in the legs, from the knees to the feet, continuing for one-half hour (after one hour and a half, second day),'. -From 8 to 8.30 P.M., severe pain in front of right ankle, followed by a soreness about the sheaths of the tendons, most on extending and flexing the foot (second day),'.--Violent pain in the right toes and foot to the instep, lasting half an hour (fifteenth day),'.

Generalities:-Feeling of languor and laziness in the evening, and aversion to mental labor (thirteenth day),'.-Took the last medicine on Friday, and the symptoms were at their height on the following Sunday, and continued with a gradual abatement till the last of the week,".

Skin.-[760.] (There is a small white ulcer upon a spot in right cheek which had been irritated by a broken tooth. Am uncertain if medicine had anything to do with it), (tenth day),".-Burning itching of the outer ear, in the evening, lasting half an hour (fifteenth day),.-Burning itching of the outer ears when in a warm room, after riding in the open air (which was not cold), and on putting the hand to the ears, was surprised to find they were not hot, though they were red. This burning has been troublesome all day when indoors (sixteenth day),.-Itching of the left cheek, nose, and chin (second day),.-A smart itching vesicle on the left wrist, at 6 P.M. (second day),.-Violent itching of left wrist, with burning after scratching, at 9 P.M. (fifth day),.-Severe biting itching in outer border of left axilla, momentarily relieved by scratching (ninth day),.

Sleep.-Sleepiness all day, with yellowness of complexion and sclerotica (ninth day),".-Very sleepy in the evening; slept sound for ten hours in succession (fourteenth day),.-Restless sleep, disturbed by dreams (ninth day),.—[770.] Restless sleep last night, disturbed by dreams, amorous and

fearful (tenth day),.-Amorous dream (fourth day),-Amorous dream, and increased sexual desire (sixth day),".-Amorous dream with emission (thirteenth day),".-Last night dreams of travelling, of robbers, of an army of cats (eleventh day),.-Vivid dreams of travelling (twelfth day),'. Fever. After dressing, seized with chills and shivering, lasting half an hour, till after a brisk walk of half a mile; with the chill a hacking cough and fluent coryza (tenth day),'.

CALENDULA.

Authority. 3. J. H. Fitch, M.D., copied from MS.; a man, aged twentyseven years, took 15 minims of a strong alcoholic tincture, at 10.30 A.M. and 4 P.M. (first day); same at 11.45 A.M. (second day); same at 2.15 A.M. (third day).

Very irritable, touchy. Afterwards fit of despair and deep anguish (second day),.-Nervous exhaustion (third day),3.—In a few minutes felt a disagreeable sensation in the occiput,.-Immediately felt pain in the occiput (second day),.-Itching of the scalp (after second dose),.-An unusual amount of saliva in the mouth and fauces (after twenty-five minutes),.Scraping and mucus in the throat (second day),.—Disorder of the function of digestion,.-[70.] Stool soft, covered with mucus, at 1 P.M. (third day),.-Emission of semen (third day),.-Slightly disagreeable sensation at the back of the neck, from the occiput (after second dose),3.—Pain in the left lumbar region; afterwards in lumbar region, both sides (second) day),”.—Itching of skin (second day),3.

CAMPHORA.

Authorities. 72, Wm. Alexander, M.D., Exper. Essays, London, 1770; 73, Jas. L. Brooks, Bost. Med. and Surg. Journ., vol. xix, 1838, p. 397, Miss B. took a dessertspoonful of a strong solution; 74, Mr. Clark, Lancet, 1842-3 (1), p. 300, a man, æt. thirty-nine years, ate about 35 grains of powdered C.; 75, Dr. O. E. Brown, West. Med. and Surg. Journ., 1847, Mr. A., ate bits of gum C. during an evening; 76, J. H. Beech, M.D., Penn. Journ. of Med., Feb., 1855, p. 367, a man, æt. fifty years, swallowed a quantity of nearly saturated alcoholic tinct.; 77, T. P. M., Lancet, 1857 (1), p. 384, a young lady, æt. eighteen years, swallowed a piece of the size of a marble; 78, A. Legat, M.D., Brit. Med. Journ., 1875 (1), p. 242, a young lady, æet. twenty years, took a few drops of a solution; 79, Geo. Johnson, Brit. Med. Journ., 1875 (1), p. 272, a boy, æet. fourteen years, took about 15 drops of hom. C., for a cold; 80, ibid., p. 171, a lady, et. thirty-five years, took 7 drops of hom. sol. of C. on sugar; 81, ibid., a young lady took 25 drops for a cold; 82, ibid., a man took eight doses of 3 drops each, within forty minutes; 83, W. Thursfield, M.D., Lancet, 1875 (2), p. 825, a child, just recovering from a fever, was given half an ounce of C. liniment; 84, New Remedies, 1876, p. 85, a lad, æt. thirteen years, ate two pieces of C. (about 120 grains); 85, omitted; 86, Geo. Johnson, M.D., Brit. Med. Journ., 1877 (1), p. 607, a man, æet. eighteen years, took within six hours seven doses of three drops each, cf hom. C. on sugar; 87, Chas. Hallett, Lancet, 1841-2 (2), p. 891, a woman, æt. thirty years, took about a scruple dissolved in rectified spirit of wine.

Great mental excitement, much resembling intoxication, with occasional delirium, with external laborious breathing, performed without the assistance of the abdominal muscles, great anxiety, languor, and giddiness, and occasional loss of sight, but the pupil perfectly natural; also a tressing sense of numbness and tingling, with coldness of the extremities, so severe that she was at times quite unable to walk, and as she expressed it, "they felt as if they did not belong to her;" pulse 90, very feeble,". Immediately a very faint feeling, which compelled her to lie down flat on the hearth-rug, and she nearly lost consciousness; this lasted about five minutes. When I arrived, her face was very pale, and her pulse was weak. She was very drowsy after she got to bed,.-He immediately became insensible; was soon found pulseless, with his extremities cold, and his face and lips pallid,".-[920.] Within five minutes after the last dose, without the slightest warning, he had a severe epileptic fit, in which his tongue was badly bitten. Ever since he has felt "queer," complaining of a peculiar cold sensation on the tongue, extending for about half an inch from the tip,.-A most vacant expression of conntenance, eyes wandering about the room, speechless and powerless. Soon had a violent epileptic fit, which lasted for about two minutes. She went into a state of stupor, and in about half an hour vomited freely, the matter ejected smelling most strongly of Camphor. In the morning she complained of violent pain in the head and chest, and still the taste and smell of Camphor were most disagreeable; her mouth was slightly distorted,".-A fit of epilepsy, which lasted about ten minutes, followed by an extraordinary state of exhaustion. The extremities were cold, the surface was covered with clammy sweat; the pulse frequent and scarcely perceptible, and the pupil dilated. When roused he had scarcely power to articulate. Occasional suppression of the urine for three months afterwards,".-Violent convulsions and nervous sequelæ, which continued for several months,.-Convulsions; speechless, but perfectly conscious of all that was going on around him,. Breathing slow, stertorous; pulse 98 and forcible; veins of forehead distended and tortuous; countenance livid, and covered with perspiration; convulsions (after half an hour), violent, racking the whole frame, in which opisthotonos was considerable; whole surface red with capillary congestion, the eyeballs injected and prominent for an instant, and then the eyes forcibly closed, loud moaning, grinding of teeth, and blowing of bloody saliva through the closed teeth (after three-quarters of an hour); this continued for about half an hour, when the opisthotonos gave place to rapid rolling over and over, now this and sometimes that way, burying the face sometimes for a moment in the bed, so that respiration was sometimes difficult,.-Burning of the mouth, throat, and stomach (immediately); convulsions (in fifteen minutes); black in the face; body arched backwards; the teeth so firmly clenched that nothing could separate them; the eyes wide open, pupils quite insensible to strong light, but neither contracted nor dilated; the eyeballs were rapidly rolling from side to side; the pulse was at times hardly to be felt; at others it was full and bounding; the breathing was gasping, with long intervals between each gasp (in three hours),-Immediately became very giddy and unwell; threw her arms about her sister, and was seized with strong convulsions. In about a quarter of an hour there was free vomiting, and she remained unconscious for some time longer. Some time later she complained of headache and giddiness, and was evidently confused; pulse quick; skin

moist,.-After four hours the child was observed to do something which elicited the remark, "Are you dreaming?" No reply was given by the child, and it was noticed that something was wrong with him; his eyes were fixed in a stare, and he stood motionless and unconscious. His brother took him up to carry him to an adjoining room, when he immediately became convulsed and perfectly rigid, with his head and legs bent back, so that he could only be placed on his side upon the floor. The convulsions increased until the flesh from the head to the shoulders became purple, and the pulse decreased rapidly until it could not be felt. The body then lost its rigidity, and was apparently lifeless; but in about ten seconds the pulse could again be felt, the convulsions returned, and the child foamed at the mouth. Applications of cold water brought him around in about four minutes; violent vomiting then ensued; he was hysterical for a time, but within an hour he was so far recovered that he could be put to bed,.

[930.] First Experiment.-I took one scruple of Camphor inclosed in a little of the pulp of tamarinds. It made no alteration on the height of the mercury in the thermometer at my stomach. But twenty minutes after, my pulse beat only 66; whereas, before I took the dose, it had beat 68; some time after this it was reduced to 65.

Second Experiment.-I took two scruples in a little syrup of pale roses; which immediately caused a sensation in my mouth, something like that occasioned by taking strong peppermint-water, but much more disagreeable. On looking at the thermometer at my stomach, the mercury, ten minutes after the dose, was fallen one degree; and my pulse, which before was 77, now only beat 75. Twenty-five minutes after the dose, the mercury was risen to the same height at which it had been before I took it, and my pulse was again at 77.

Long before this time, however, I began to feel an unusual lassitude and depression of spirits, accompanied with frequent yawnings and stretchings, which stole upon me by slow and almost imperceptible degrees; till, at the end of three-quarters of an hour from their first appearance, they were grown extremely troublesome. The mercury in the thermometer remained at the same height as it had done before the dose; but my pulse was now fallen from 77 to 67.

Soon after this, my head grew so very giddy, that it was with great difficulty I could walk across the room; when feeling myself, as I thought, stifled, I imagined the fresh air would remove that symptom, and therefore opened the window and looked out; but everything in the street appeared to me in the utmost tumult and confusion; in which, imagining that I was involved, I felt myself in danger of losing my balance, and tumbling from my position. I therefore staggered from the window to my bed, and having a book with me, read several pages of it; but had no distinct idea of any one sentence, but far less could I connect two or more of them together, so as to comprehend the meaning of the author. At last, being able to read no longer for the tumultuous motion which I perceived among the letters of the book, and finding it had no power to divert the attention of my mind from the uneasy sensations which disturbed me, I arose to see whether I could walk any better; but to my great mortification, found my head more confused, and could hardly walk any at all. I then returned to the bed, and being a little thirsty, called for some mutton-broth to drink. It being dinner-time, the servant, instead of bringing the broth, covered.

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