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the arms (after three hours, third day).—Prostration and weakness in the right arm, by writing (eighth day).-[120.] Weakness and prostration in the arms and wrists (after one hour, thirteenth day).—Great fatigue in the arms, evening (fourteenth day).—Prostration of the arms (fifteenth day).
- Isolated sore throbs in the right arm, and under the right arm-pit (after one hour, first day).—Isolated throbbing or shooting in the arms (eighth day).—Throbbing as formerly, in the arms (thirteenth day).-Cracking in the left shoulder; this has never been experienced before (fourteenth day). -Soreness in the shoulders and neck (soon, fifth day).-- Pain under the right axilla, extending to the pectoral muscles (fourteenth day).- Pain under right axilla (fifteenth day).--[130.] Painful soreness under the arms (fourteenth day).- Pain of great intensity in the deltoid of the left arm, evening (fourteenth day).-Weary pain, upper arms (after one hour, second day).- Weakness and soreness in the biceps (after two hours, fifth day).Sensation of pain running along left upper arm, becoming stationary (fourteenth day).-Pain in left elbow, morning (third day).-Soreness in the right wrist, extending upwards to the elbow, as if traceable in the flexor carpi ulnaris muscle (after two hours, fifth day). - Soreness, left wrist (after one hour, second day). --Soreness and pain in left wrist (fourteenth day).- Throbbing and shooting pain in the wrist (after two hours, fifth day).—[140.] Soreness in the fingers and thumb; weakness in the hands in writing (after three hours, third day).
Inferior Extremities.-Cracking iv the joints of lower extremities, by walking (fourteenth day).- Weakness in the lower extremities, by walking (after two hours, fifth day).- This morning, felt great prostration in the legs, and sureness in the lower part of the spine ; the weakness and pain are more perceptible in the left than in the right thigh (seventh day). --Weakness in the lower extremities increasing, extending from the hip to the knees (after one hour, thirteenth day).-Pain in the thighs by walking (after one hour, first day).-Transitory, short, sudden pains in thighs (after one hour, second day). --Rheumatic moving aching in the left kuee, very intense (sixteenth day).-Sore throbbing pain in right knee (after one hour, first day).--Immediately after second dose sharp throbbings or shootings in the knees, and contractions, cramplike, in the muscles of the thighs (soon, thirteenth day).-(150.] Pain in the knees; sore throbbings (fourteenth day). -Great weakness in the legs and prostration, evening (third day).- Pain in the lower part of the legs (fonirteenth day).-Throbbing sore pain in legs (after two hours, fifth day). -Soreness on the soles of the feet (fifteenth day).
Generalities.-Loss of flesh since commencement of proving (fifteenth day).- Appearance of general illness observed by my friends (fifteenth day).- Increasing weakness avd pain in the back (sixth day).Lassitude and weakness (thirteenth day). -Great lassitude and prostration (seventeenth day).—[160.] Soreness to touch (fourteenth day).- While at first the pains had a nervous character, they are now decidedly muscular and lasting longer (fifteenth day).— The action of the drug appears to be more on the spine and nerves than on the muscles. The pains are of short transitory character, and not of a continuous muscular pain. Except in the spine, where the pain is not constant, it appears as if the action could be traced along the anterior branches of the saphenic nerves, and perhaps along the saphevic vein; the pain in the groin is unquestionably the result of the crural nerve.--It was some time before the irritation in the bladder and urethra ceased, also the prostration and weakness lasted several days, and the isolated troubles through the arms, legs, and thigh continued several weeks.
Skin.-Painful itching burning by walking, under the big toes, and itching in the sole of the right foot (fourteenth day).—Itching of the skin (fourteenth and fifteenth days).-Itching in the face (after two hours, second day).
Sleep.- Very sleepy during the day, and constant yawning all day (eleventh day). - Great inclination to sleep (twelfth day).-Great inclination to stretch (fourteenth day).—[170.] Heaviness and sleepiness (seventeenth day).—After waking could not fall asleep again; confused dreams (fifteenth day).—A very restless and sleepless night was passed (tenth day).-Restless sleep during the night (fourteenth night).- Talking in sleep (fifteenth night).—Night full of dreams (fifteenth day). Fever.-Cold
and chilly (after one hour, first day).- Chilly; pulse 50 (after one hour, first day).-Shivering and chilliness immediately after taking the dose (soon, third day).-A cold sensation and tightness about the scalp (after two hours, fifth day).-[180.] Rigors and chilliness (eighth day).- Rigor and chills all over the frame (fourteenth day).—Chilliness and heat in the face (fourteenth day).-Hands and feet cold (fourteenth day).
Authority. John Popham, M.B., Lancet, 1849 (2), p. 635, a large number of Irish during the famine ate freely of wild corn kale or Brassica napus.
They all exhibited indications of deteriorated health, the hue of the skin being uniformly sallow and muddy-looking, totally different from the brown discoloration caused by exposure to the sun ; the surface was always covered with that colorless downy hair, so characteristic of what the country people here call “impoverished blood.” An ædematous state prevailed generally of the whole body, but always of the face and lower extremities, the former sometimes being swollen to an enormous extent, the distended state of the eyelids and upper lip especially producing remarkable deformity. The abdomen was tympanitic; the bowels torpid; the mucous membrane of the mouth and pharynx was inflamed, and in some parts ulcerated, and the gums spongy; the appetite was usually greater than natural, in some cases voracious; the urinary secretion was deficient and irritating, and that of the skin suspended; very distressing frontal headache and tension was also complained of; but the most curious symptom, next to the cedematous appearance of the patient, was the state of the hands and feet, which were dry and shrunken, with blotches of a deep red, resembling burns, on the backs of the hands and dorsum of the feet, the fingers and toes being frequently cold and livid. Similar blotches existed on the nose and forehead, and these varied in their consequence from simple discoloration to ulceration of a most troublesome description, terminating in loss of the cuticle, and dropping off of the nails, with a marked disposition in the aggravated cases to gangrene.
BROMIUM. Authority. 27, Heimerdinger, die Wirkung des Broms, und ein Brom. Präparate, Inaug. Diss., Tübingen, 1838.
Took in morning fasting, 5 drops in ļounce distilled water; after an hour there was a slight nauseous reminiscence of the taste of the drug. At another time took 8 drops in 1 ounce water, holding the nose while swallowing ; rough cough. After an hour repeated eructations. The appetite was diminished. The disgusting taste of the drug lasted all day. In the afternoon there was thirst,9%.
Authorities. 44, C. E. Goate, M.D., Lancet, 1868 (1), p. 610, a child, aged three years, ate freely of the berries ; 45, E. W. Berridge, M.D., Am. Journ. of Hom. Mat. Med., vol. ix (New Series, 5), 1876, Berridge took 2000th (Jenichen) by olfaction for cough ; 46 (L'Art. Med., 1877, 92), Recueil des Travaux de la Soc. Med. d’Indreet-Loire, Tours, 1878, a map took as a purge an infusion of a large quantity of the root.
In about half an hour she became giddy, and during the night furious delirium supervened; the pupils became dilated ; vomiting incessant, but not accompanied by diarrhea. As morning approached, the delirium ceased, and she became comatose, with occasional subsultus tendinum,“. Occasional sudden sharp pain in left lower second bicuspid, somewhat as if the tooth were being pulled out; it was felt on and off during the day, worse morning and evening; in the evening it was sometimes intermixed with shooting in the tooth ; the pain (of pulling out) was worse on pulling with the fingers (second day). In morning once the same pulling out pain, but less; in evening several times and more severe, worse by pulling at the tooth, and intermixed with shooting in the tooth; the pain sometimes ended in a shoot; the tooth is sound (third day), --Great prostration ; extreme coldness ; numbvess of the extremities; convulsions with tonic contractions of the extremities; opisthotonos; thorax iinmovable, inspiration associated with a remarkable depression of the pit of the stomach, 16.
Authority. 16, Dr. R. de Gumbleton Daunt, Dublin Med. Press, Sept. 25th (Pharm. Journ., Second Series, vol. iji, 1861-2, p. 291), the skin contains glands which secrete a milky glutinous fluid when the toad is put to pain or irritated; this is scraped off and dried in Brazil.
It produces incurable obstruction and enlargement of the liver, and a speedy death,'.
Authorities. 10, Habn. Month., 11, 1876, p. 509, W. McGeorge and M. B. Tuller, Report of Bureau of Mut. Med. to West Jersey Hom. Med. Soc.; 11, E. Clark, M.D., U. S. Med. Invest., New Series, 11, 1879, p. 345.
Sensation of constriction of the heart, as if an iron bandt prevented its normal movement,'".— I inhaled the odor of recently prepared tincture, and immediately thereafter rode to see a patient. When I had ridden a mile I had an uneasy sensation in my stomach like food difficult of digestion, but soon after entering the sick-room thought po more of my stomach. Thirty minutes later found it difficult to cross the sidewalk to enter my carriage. After ten minutes more the vertigo had increased, there was stricture about the chest and stomach, pain in the heart and head. Arrived home and threw myself on the sofa. Now there was violent vertigo, causing me to stagger and reel; violent pain in the head, chest, and stom. ach; head felt full as if there were congestion. Pressing pain in the head, like a great weight on the vertex, pressing in the temples, pulsating in the temples, ears, and eyes, as if they would burst outwards. Weakness of sight, objects were not seen clearly; intolerance of light and sound. Tongue dry and coated, slime in the nares and throat, very thirsty, satisfied with small quantity of water at one time. Profound nausea, lay for hours with my bowl near me, retching many times, with copious discharge of mucus. Terrible pain in the stomach, with pressure from without in; constriction of the scrobiculus, extending to the hypochondria, and as high up the chest as the fifth rib, as if encircled by a hot iron cincture, having involuted edges of an inch in size, pressing more and more, from hour to hour, till respiration was most difficult and distressing. Some cough with much mucous expectoration, which greatly aggravated my sufferings. Attacks of difficult respiration, amounting almost to suffocation, with increasing hard and painful beating of the heart. The heart felt as if compressed violently, and as violently struggled to burst its bands. Pulse very irregular; could not suppress a groan, so great was my distress. At the same time severe pain in the spine, worse in the lumbar region, pressing down the glutei muscles to the inferior extremities. Tearing pains in the shoulders and arms; worse at first in the joints; after twenty-four hours 'worse in long bones. These symptoms increased for about twelve hours. Ipecac. was used for the nausea and the pain in the head; after several hours found no relief. Verat. vir. was taken with like nil results. Camphor was used in drop doses once in fifteen minutes for several hours, nil. A most miserable night was passed, not a symptom disappeared; but the nausea was less distressing, and the iron band was less distressingly close around me. The heart struggled less violently; the tongue was coated thickly, whitish; thirst considerable; the pains in the extremities remained unchanged. Three mushy motions from the bowels during the forenoon, with pain. During the second day I took Bryonia for the pain in the head with some relief. Night found me still in bed, upable to raise my head for vertigo; not a symptom had left its quarters, only a little less violent. During the second night I had a few hours of disturbed sleep, scared with dreanis ; awakened on the third morning somewhat refreshed, and was able to leave my bed for a few hours. All my remedies having failed to relieve the bone pains in my extremities, I now took Eupatorium perf., and was soon so far relieved that sleep came, to my great comfort. The fourth morning found me relieved of all severe suffering, but well in no part which had been the seat of suffering. In about ten days the symp
† Lippe in his Materia Medica and translation of Rubini, makes this word rend "hand,” while in Allen's Encyclopedia, and Hale's New Remedies, it is written “ band."
toms disappeared, and I look back upon the horrors of those days of anguish as one escaped from the greatest danger. I remained weak for sev. eral weeks, with frequent attacks of palpitation,".
CADMIUM BROMATUM. Cadmium bromide, CA Br..
Authorities. 1, G. A. Wheeler, M.D., Bost. Med. and Surg. Journ., vol. xcvii, 1876, p. 434, Mrs. N. put less than a teaspoonful into two-thirds of a tumbler of water, gave her mother, Mrs. R., half of it, and took the rest herself; 2, Dr. W. took what would adhere to his wet finger.
Found both ladies vomiting severely, and complaining of extreme pain and burning sensation in the stomach. Mrs. R. was also purging freely, though her daughter was not. The vomiting and purging lasted fully five hours, and during a part of the time the pulse was imperceptible in either patient. After this period the symptoms ameliorated, and they both fell asleep. For several days they were both confined to their beds, and were obliged to be extremely careful as to what they took into their stomachs. Mrs. R. has since suffered with some cerebral symptoms which betoken a tendency to apoplexy,':-A severe burning sensation in the mouth, esophagus, and stomach, which lasted perhaps an hour,'.
CAJUPUTUM. Authorities. 2, W. Cattell, Brit. Journ. of Hom., vol. xi, 1853, p. 169; 3, a proving submitted to the Faculty of Hahn. Med. College, by George Robins Parsons, M.D., of Kankakee, III., February, 1874.
During the summer of 1869 I made the following proving: Took 7 drops on a lump of sugar at 9 A.M., 10 drops on sugar at 2.30 P.M. (first day); 20 drops on sugar at 9 A.M., 22 drops in 3 ounces of water at 2.30 P.M. (second day); 25 drops in 3 ounces of water at 9 A.M., 35 drops in 4 ounces of water at 3 P.M. (third day); 40 drops in 3 ounces of water at 8.30 A.M., 50 drops in water at 3 P.M. (fourth day); 60 drops at 9 A.m., and got no particular symptoms ; 70 drops at 2.30 P.M. (fifth day); stopped taking the drug, as
my throat would get so bad that I would choke to death (sixth day).
Mind.—I do not want any one to speak to me; nevertheless I like to be where I can see persons and hear their talk. Can't bear to look inside the books I usually study; can think of a thousand things in a minute (one hour after first dose, second day),'.—[60.] Want to walk in a slow and very dignified manner, and prefer to walk alone (one hour after second dose, second day), --Can't think of anything; ideas come slow; can't bear to do any kind of work or study (one hour after second dose, second day), ".-Can't think of study (eighth day),'. — Felt stupefied and completely intoxicated all the afternoon (after second dose, fifth day);".
Head.-Feel dizzy when I walk, feel as if intoxicated, can hardly walk straight, feel as if I should stumble over my own legs (three hours after first dose, fourth day),.-Sensation and feeling as if the head was as large as a half a bushel (soon after first dose, fourth day),.-Full and dull heavy feeling all through the head (one hour after second dose); this feeling all settled in the occipital region (two hours after second dose), and