the Atropia was dropped in to facilitate a proper examination of cataract. The right eye only was affected, though the drops had been put in both. The patient had been seen on two occasions before the Atropia was used, and there was no occasion to suspect any glaucomatous condition. The symptoms came on within a few hours of the drops being used,".-In one case there was acute conjunctivitis, lasting several days; in the other, erysipelas of the lids, spreading to the face and head, was excited on two occasions, a period of six months intervening,.-In four or five days she began to have difficulty in seeing with her right eye, being the eye upon the same side of the body to which the plaster had been applied. Upon examination the pupil was seen to be considerably enlarged, and the eye was undoubtedly strongly under the action of belladonna, the left eye being normal," [520.] Dr. Rothhaupt, aged twenty-five years, whose normal pulse was 60 to 64, at this time 64, injected 0.00025 gram Atropia; pulse gradually fell in five minutes to 52; during the next twenty minutes it fluctuated between 50 and 60; after twenty-six minutes it was 48; it slowly but gradually rose, until after an hour it regained its normal rate, and after an hour and a quarter continued regular at 60. Another man, aged twenty-five years, with pulse constantly at 68, took 0.0005 gram; after seven minutes pulse 60; after thirty-three minutes 68; thirty-eight minutes 72; sixty-two minutes 78; seventy-seven minutes 78, where it remained constant. K. R., aged forty-six years, injected milligram; pulse rose to a maximum of 70 beats. R. Z., aged twenty-five years, with a pulse of 60; rose to a maximum of 68. B., aged twenty-five years, pulse 64; rose to a maximum of 74. O. Z., aged twenty-one years, pulse 60; rose to a maximum of 80. The same prover, K. R.; the pulse fell after ten to twenty minutes 10 beats. R. Z., the same. B.'s fell 10 beats in one to ten minutes. O. Z.'s fell 6 beats in ten to twenty minutes. Another series of experiments with 0.00075 gram; pulse 62, fell after twelve minutes to 48; after thirty-nine minutes it was 78; after forty-nine minutes 86; after which it gradually returned to the normal. Same man subsequently injected 0.001 gram (or 1 milligram), pulse 60; in seven minutes and threequarters it fell to 52; after thirty minutes it was 102; after which it returned to the normal and did not fall below it. Another proving, with 11⁄2 milligram; pulse 68; in twelve minutes 52; in forty minutes 104; after which it gradually returned. After an injection of milligram, the maximum fall of the pulse was reached in twenty-six minutes, and lasted fifty minutes. After milligram the maximum was reached in sixteen minutes, and lasted forty-one minutes; after milligram the maximum fall was reached in thirteen minutes, and lasted twenty-one minutes. After 1 milligram the maximum fall was reached in seven minutes and lasted fourteen minutes. After milligram there was no rise in the pulse. After milligram the maximum was reached in eight minutes, and it lasted fourteen minutes. After milligram the maximum rise was reached in twentysix minutes, and lasted one hundred and nineteen minutes. After 1 milligram the maximum rise was reached in forty-two minutes, and lasted one hundred and sixty-four minutes,".-In half an hour vertigo occurred, with wanderings of vision. In three-quarters of an hour all the symptoms of poisoning with Belladonna were present, flushed face, enormously dilated pupils, and incessant hallucinations. The patient drew his coverings over him, and attempted to seize objects that he saw in the air. On attempting to rise his legs failed under him, and he could not take two steps without being assisted. His pulse was 120 and full. In the evening he became

more calm, but the bladder was distended, and he was unable to empty it, so that the catheter had to be used. He lost all recollection of his illness except his delirium and its accompaniments,".-Delirium, uncertainty in his gait, with absence of sleep and difficulty of swallowing. On the day after but one, he had another attack of delirium, somewhat resembling delirium tremens, seeing imaginary persons in the room,3.-It had a distinct persistently bitter taste, and produced a numb sensation upon the tongue, somewhat similar, though less in degree, to that produced by aconite. In about ten minutes it produced a sense of nausea, which continued to increase until an effort was made to vomit. Although the effort at vomiting was made several times, nothing was thrown up. To this intense thirst succeeded, and a frontal headache, which was lessened by closing the eyes. Next a dryness was felt in the throat, and the tongue and mouth felt dry and feverish. These symptoms were not relieved, and only mitigated for a short time, by drinking water. This dryness of the throat increased, and was persistent for several hours, causing at first almost constant deglutition, and towards the last a strong effort to avoid deglutition, which had become painful. During the first two hours the pulse was less frequent, but afterwards became smaller and more rapid. The eyes soon lost all control of distance; a printed book held at the usual distance was a perfect blur; held at a long distance, letters could be distinguished, but the words upon looking at them, soon ran into confusion. Objects at a distance could be plainly seen, even a little more plainly than natural (hypertrophia), but near objects, though for a moment distinguished, soon lost their distinctness. A numb or crawling sensation, a formication, was felt down the back, upon the arms, and back of the hands. This formication was intense and very unpleasant upon the palate. Light became unpleasant to the eyes, causing pain deep in the eyeballs. Motion became unpleasant, and if the feet were lifted in walking, the floor seemed to recede from them before they again were put down. A sliding of the feet along the floor seemed to be the only safe way of locomotion. The head began to be dizzy, and for fear of falling it was necessary to be seated in the easy chair. Thirst at this time was very great, but only little water could be taken at a time, as the effort of swallowing was unpleasant. A languid feeling came on, as the semirecumbent position was assumed, and whether sleep, accompanied with wild dreams, or waking hallucinations followed, it was impossible to tell. Whether the brain was troubled with hallucinations, or with wild fantastic dreams, they were exactly the opposite of those produced by Cannabis indica, for all the imaginations and conversations were of the long past, none of the future. Whether there was total blindness, or merely an imagination of blindness, could not be remembered; but, if there was blindness to the external eye, the mind saw all its images with great distinctness, and the impress of them was left with vividness. There was consciousness of individuality, but the actions were performed by others, who were embodied spirits of those long since departed. Lengthy conversations of a most pleasant character were held with Plato, Alcibiades, Aspasia, and others. How long this state lasted cannot be told; but sound, profound sleep must have followed, for consciousness to external objects did not return till sixteen hours after taking the Atropia. Awaking took place suddenly; there was no pain, no headache, nothing abnormal but a languor and disturbed vision. The bladder had not been emptied during these sixteen hours, and although a large quantity of water had been drunk, but a moderate quantity of urine was

VOL. X.-24

34

passed. The vision was not clear for several days,".-In about twenty minutes her hands were tremulous and her eyes closed; but she was quiet and became drowsy. In a few minutes the agitation increased, until it became more violent; she at the same time kicking out her feet and throwing her arms forward. On attempting to move her to her bed, it was found that her limbs were powerless, and that she was unable to stand, so that she had to be carried. Her face was very much flushed. In a few moments a meddlesome and pleasant delirium set in, in which she picked at her clothes, tried to get out of bed, and imagined she was sewing, or nursing her child, or engaged in shopping with her sister. These hallucinations lasted for about ten minutes, when she sighed and yawned repeatedly, and "dropped into a comfortable sleep" the interval between the taking of the medicine and the sopor having been rather more than one hour;, after three hours' unconsciousness, and laboring under a heavy stupor. The eyes were closed, the pupils dilated, and the muscular system was greatly relaxed, excepting a condition of trismus, which was well marked, and deglutition was almost impossible. The respiration was labored and very much like that of an intoxicated person. The pulse was quite good, but neither it nor the respiration was counted. Countenance somewhat livid. Lids closed, conjunctivæ slightly injected; eyes had a fixed and brilliant stare. The tongue, roof of the mouth, and soft palate were glazed and parched,.-Pupils dilated. Excessive dryness of mouth and throat, with a sensation of burning and choking. Great difficulty in swallowing. Pulse 130. Great dizziness, and a sensation of weight on the top of the head and over his eyes. Frequent rigors and loss of muscular power, being unable to walk, or as he expressed it, "to feel his legs." Very restless and agitated. Great difficulty in articulation. Micturition accomplished only after some trouble,.-In less than five minutes, I became aware that I had an overdose; my heart began to labor heavily, and to my feelings, roughly, at the rate of about fifty per minute, accompanied by a sore feeling immediately over the base of the heart. This continued about ten minutes, and was immediately followed by intense thirst, dryness of the mouth and throat, with great perversion of sensation, everything tasting intensely acid. The skin of my whole body began to feel turgid and swollen, and in about an hour and a half was covered with a rash precisely similar to that of scarlet fever. There was also diplopia; during the evening I was completely unable to read the newspaper. Next morning there was power to read with one eye at once; and in the evening the disturbance of vision had entirely gone, as well as all other signs of the action of the drug,".-Insensible and comatose. Pupils largely dilated. Face flushed and swollen,.-In a state of intense excitement; skin greatly congested; face, hands, and whole body swollen and bloated; mind delirious; sensibility suspended; violent clonic spasms at times of the limbs; pupils dilated to their fullest extent; intense thirst; speech thick and clogged; tongue and throat swollen (after two hours),-In one hour, face flushed, full, strong, hard, and bounding pulse, almost stertorous breathing, with much somnolency, and great impairment of all the senses. When aroused and raised up he would look wildly around, and when addressed in a loud voice would mutter some incoherent words. There was great muscular tremor, and muscular weakness, particularly of the lower extremities, insomuch that he was unable to stand when aroused, although at the same time he exhibited considerable strength

in his arms. He passed his urine involuntarily,".-[530.] Delirious, but not wholly unconscious, starting frequently from a brief period of repose and screaming with pain or terror, and clutching violently with the hands. The flexor muscles of the extremities, the upper especially, were principally affected. The muscles of the spine occasionally contracted so as to jerk the head backwards with electric quickness. Pupils dilated to the utmost. Pulse 120, and diminished in force. Surface dry and hot, and covered with a strongly marked scarlatinoid redness (after one hour),“. Giddy and strange feeling in the head so that he could not see. Throat of a deep red hue, sore and could not swallow. Pupils widely dilated,".Dryness of mouth and throat. Sour taste in mouth. Dryness and burning in the stomach. Repeated vomiting; partial delirium,".-Pupils widely dilated and insensible to light; gait staggering, the patients being unable to stand alone; there was great thirst, and the elder patient had incontinence of urine. They both talked and laughed wildly, but answered questions readily. The intellect was confused, both patients fancying they were still at home, and attempting to arrange furniture,.-Staggering on walking. Excessive nervousness. Giddiness. Loss of power over legs. Pulse rapid. Unconscious. Pulse weak and irregular. Skin dry. Face flushed. Violent delirium. Tongue dry and brown. Respiration laboring and quick, accompanied by flapping of cheeks. Twitching of some muscles of arms and legs. Catching at imaginary objects. Chest, râles about base. Unintelligible talk in sleep. Tympanitis over abdomen. Tenderness over abdomen. Soreness at pit of stomach. Urine high-colored, turbid, of an amber color; chlorides present; no albumen ; specific gravity 1015. Pain over right side of chest. Cough and expectoration; sputum rust-colored and scanty. Absolute dulness of chest as far as spine of scapula on right side behind, with tubular breathing and bronchophony. Over left lung, posteriorly, rough breathing, otherwise breath sounds healthy,".-Dryness of the throat. Confusion of vision. Pupils largely dilated (after four hours and a half). Slightly delirious, and staggered as if under the influence of alcohol (after five hours); he seemed to have hallucinations, for frequently he would put out his hands and attempt to grasp some imaginary object (after five hours and a half). Drowsy and stupid, but he recognized me and asked me in a sort of maudlin manner what was the minimum dose, meaning the minimum lethal dose; he could be easily aroused, and although his answers to questions were given in an indistinct tone they were quite rational, and some remarks that he made indicated that he appreciated the danger of his condition (after five hours and a half); the coma steadily increased, and the prospects seemed almost entirely hopeless; his head hung upon his shoulders in a perfectly limp state; there was complete unconsciousness, from which he could not be aroused; for about half a minute respiration ceased, and artificial respiration was resorted to, and could only be maintained at eight in a minute (after ten hours). Pulse 140, full and strong (after five hours and a half); 120, full, but not so forcible as before (after seven hours and a half); 120, less force (after ten hours). Respirations 20, and not in any respect abnormal (after five hours and a half); about 24 (after seven hours and a half); for about half a minute it ceased, and artificial respiration was maintained at 8 per minute (after ten hours); improved (after eleven hours),.-Delirium, to which was soon added all manner of absurd hallucinations. Pulse rapid and feeble. Skin flushed and dry. Tongue dry

and brown. Great thirst. Dryness of the throat,".-In a few minutes the child turned a deep red, like "scarlet fever," over its face and the upper half of its body; the perspiration was checked, and the skin became hot and dry. This continued for five hours (after a teaspoonful). The same redness appeared, but only lasted for half an hour (after 6 drops),".

BAPTISIA.

Authority. 13, C. Wesselhoft, M.D., Trans. Mass. Hom. Med. Soc., vol. iii, 1875, p. 457, took 3 drops of the 5th dil.

In five minutes to half an hour, aching pain of occiput, extending from ear to ear, and from nape of neck to vertex (first day),.-Immediately after taking medicine, aching pressure over whole occiput, from ear to ear, and from vertex to nape of neck (fourth day),".-[370.] For two days, severe sleepiness, dulness and drowsiness; weakness of memory; fall asleep easily while sitting or writing (second and third days). Great sleepiness all day while sitting still; irresistible desire to sleep in carriage; was so exhausted and sleepy after a light dinner, at 3 P.M., as to be unable to sit up any longer. Refreshed after an hour of imperfect sleep, but felt sleepy and tired all the evening (fourth day). Immediately after breakfast, great sleepiness, would like to lie down and sleep, though I slept well all night. Head dull and heavy; mental work costs great exertion; great disinclination to exert the mind in any manner. Excessively sleepy all day; gaping while conversing with people; fall asleep in the horse cars; and can scarcely keep awake while driving. Sleep after dinner refreshed me somewhat, but sleepiness returned in the evening with nausea (fifth day),".

BARYTA ACETICA AND CARBONICA.

CORRECTION.-In Hahnemann's Chronische Krankheiten, last edition, vol. ii, these two salts were combined. Hahnemann indicated by a dash, the symptoms belonging to Acetica, and the editor separated these for the "Encyclopedia" (an unnecessary refinement, probably).

Recently Dr. Hering has communicated to the editor a discovery of errors in the original text of Hahnemann. The provers of Acetica, from Hahnemann, should be Adams, Stapf, Hartmann, Ruckert, Gross, and Hartlaub. Provers of Carbonica. Hahnemann, Rummel, Hartlaub, aud Nenning.

The symptoms recorded by Neumann under Baryta carb. were observed, after the muriate.

Symptom 185 of Acetica should be revised so as to read at the end, “as in dysentery," instead of when at rest;" the error arose from a misprint in the original, which should be Ruhr instead of Ruhe. (See Chronische Krankh., symptom 309.)

BARYTA CARBONICA.

Correction by Berridge in a letter to Dr. Allen.

Symptom 191, for "his side" read this side [i. e., left side].

Authority. 26, Reincke, Vjs. für Ger. Med., 1878, S. J., 180, 14, a