costive, and each defecation was followed by several drops of dark blood, attended by a bearing-down sensation, not a griping, nor a true tenesmus, but more as if the bowel would prolapse from its own weight; this lasted about two weeks, after which my bowels became regular,'.-No stool since I began the proving (third day); stool this afternoon for the first time, hard, and covered with mucus (fifth day); bowels moved freely (seventh day),3.

Urinary Organs.-Uneasiness in region of kidneys (third and following days),'.-Kidneys very sore (seventh day),'.-An increase in the quantity of urine; sp. gr. 1021, very light-colored (second day); urine copious (third day); very copious (fifth day),.-A large quantity of urine; the bladder felt very full (first day); have urinated oftener than usual today, and a large quantity; sp. gr. 1026, color clear (second day); sp. gr. 1019, in the morning; urine more profuse than is natural; sp. gr. 1029, in the evening (after walking a great deal during the day), (third day); more copious, sp. gr. 1030, in the morning; still copious, with uneasiness about the kidneys; sp. gr. 1032, in the evening; sp. gr. 1036, at 10 P.M. (fourth day); great urging to urinate, the bladder feels full to overflowing; sp. gr. 1022, in the morning; 1024, at 12 M.; uneasiness of the whole urinary tract; sp. gr. 1034, at 10 P.M. (fifth day); 1028, in the morning; whole mucous membrane of the urinary tract feels irritated; sp. gr. 1030, small quantity of urates, more phosphates at 9 P.M. (sixth day); urine not so profuse; uneasiness of kidneys still present; vesical tenesmus after urinating (seventh day); urine of a deeper color (eighth day),-Urine has, in health, a sp. gr. of 1020 to 1025; at 3 P.M. to-day it was 1030, limpid and copious (first day); sp. gr. of urina sanguinis 1032; sp. gr. of urina chyli 1034 (second day); sp. gr. urina sanguinis 1030; sp. gr. urina chyli 1034 (third day); urina sanguinis 1030, urina chyli 1032, urine much less in quantity (fourth day); urine as day before yesterday, but scanty (sixth day); urine, sp. gr. 1023, much less in quantity (seventh day),.

Respiratory Organs. —[40.] Some irritation in the bronchia, causing a short, hacking cough (second day),'.-Dry, hacking cough occasionally (second day); have coughed all day (third day); ceased medicine, it is so bitter, and provokes such a cough that it annoys me; almost incessant hacking cough (fifth day),2.-Felt oppressed in breathing, or rather that I was breathing air loaded with impurities after retiring; pulse slow and irregular; this lasted about half an hour, after which I slept as usual (second day),'.-Some dyspnoea, disappearing on going into the fresh air (seventh day),'.

Chest.-Lungs feel as if full of blood, at 2 P.M.; at 10 P.M. had to leave a close room on account of the oppressed feeling in my chest; on coming into the fresh air I was obliged to cough much; this was followed by hiccough and profuse expectoration (fourth day),'.-The lungs feel as if in the first stages of pneumonia (fifth day),'.-Chest feels tight and oppressed (second day),.-On reclining or lying down my chest feels distressed, as from deficient aeration of blood in the lungs (third day),'.

Pulse.-Pulse 72, slow and irregular for half an hour (second day); 61 (third day); 64 (fourth day); half an hour after the first dose the pulse was very weak, then it began to grow full and rapid; this lasted two hours; after retiring at night, pulse very weak, intermitting one or two beats; once. it stopped for a few seconds; this was followed by a bounding pulse (fifth day); 72 (seventh day),'.-Pulse 84, full and strong (second day),.-[50.] Pulse 70 at 8 A.M.; 72 at noon; 75 at 9 P.M. (first day); 72 at 9 A.M.; 70

at noon; 76 at 4 P.M.; 76 at 10 P.M. (second day); 68 at 7 A.M.; 70 at noon; 74 at 9 P.M. (third day); 72 at 7 A.M.; 74 at noon; 80 at 9 P.M. (fourth day); full and strong, 80 at 7 A.M.; sank to 68 at 3 P.M., but rose to 76 in the evening (fifth day); 74 in the evening (sixth day),3. Superior Extremity.-Tingling in the palm of the left hand; also in the left arm (sixth day),'.

Generalities.-Rose at 5.15, feeling dull and heavy, and with a severe headache (fifth day),.-Dull and stupid all day (seventh day),'.While in a close room, felt very faint, disappearing on going into the fresh air (seventh day),'.-In the evening I feel much better in every respect . (sixth day),3.

Sleep.-Felt as if I had not been asleep, on awaking in the morning (sixth day),'.-Slept poorly and with little refreshment (sixth night),'.

Fever.-In a few moments after retiring (after the second dose) I began to feel cold; pulse at the wrist very weak, intermitting one or two beats; once it stopped for a few seconds; this was followed by a bounding pulse; I became very warm, and my breathing stopped; my lungs felt as if I were breathing in hot air (fifth day),'.-Feet and hands cold; head hot (seventh day),'.

TRIMETHYLAMINUM.

Trimethylamin, CH,N.

Preparation, solutions.

An alkaloid found in the following plants: Chenopodium vulvaria, Crataegus oxycantha, Sorbus aucuparia, Phallus impudicus, Pyrus communis, Arnica montana, Cotyledon umbilicus, Fagus sylvatica, etc.; also in Herring-brine, Cod liver oil, etc.

Authority. M. Dujardin-Beaumetz, Nouvelles Recherches sur la Triméthylamine, Paris, 1873; 1, effects on himself, of 50 centigrams of the muriate dissolved in water; 2, another person in perfect health took 75 centigrams of the muriate; 3, results of several experiments.

This drug, according to several experiments on patients, etc., diminishes the amount of urea; in one case there was a diminution of over 2 grams during twenty-four hours, in another 2.24 grams, in another a diminution of 3 grams,.-Pulse 88 (before the experiment); 84 (after one hour); 82 (later); 76 (after two hours). There was not only a diminution in the number of pulsations, but also a modification in the force, as shown by the tracing (it shows no special modification, with the exception of diminution in the force of the heart's action),".-Pulse 78 (before the experiment); 76 (after one hour); 74 (after one hour and a half); 72 (after two hours); 78 (after four hours),'.-Temperature 37.4° (before the experiment); 37.2° (after one hour); 37° (after one hour and a half); 36.8° (after two hours),'.-Temperature 37° (before the experiment); 36.8° (after one hour); 36.4° (later); 36° (after two hours),.

TRIOSTEUM.

Triosteum perfoliatum, Linn.

Natural order, Caprifoliaceæ.

Common names, Fever-wort, Horse-gentian.

Preparation, Tincture of the root.

Authorities. 1, Williamson, Trans. American Institute of Hom., a few drops of tincture in water every day, for three successive days; 2, same, Neidhard; 3, R. Tallmadge, M.D., Hale's New Remedies, 1864, p. 1019, 2d. dil.

Mind.-Greater cheerfulness (first day),2.

Head.-Giddiness when rising at midnight, with extreme drowsiness,1. -Headache worse from sitting up,'.-Headache, which is worse in the right side of the forepart of the head, and right temple,'.-Increasing pain in the head,'.-Boring pain in the right temple at 3 A.M.,'.-Boring pain in the left temple,'.-Pain in the right side of the head, and in the back,'.— Pain in the hinder part of the head, with the sensation of weight,'. Eye.-[10.] Slight pain in the left eyeball,'.

Nose.-Sneezing,'.

Throat.-Soreness, as if from swelling of the pharynx, and pain in the oesophagus on swallowing,'.

Stomach.-Increased appetite through the day,'.-Loathing of all food,'.-Thirst, but not a very urgent desire for drink,.-Slight nausea,'.Nausea on rising, which was immediately followed by copious vomiting of very sour ingesta, attended with cramp in the stomach, and followed by perspiration, and a pain in the forehead, which was worse on the left side,. -Vomiting at 5 A.M., on rising to stool,'.-Vomiturition, attended with severe pain in the epigastrium, and drawing in the calves of the legs, almost amounting to a cramp,'.-[20.] Oppression in the epigastrium through the night,'.-At 4 A.M. the feeling of load and oppression in the epigastrium, with throbbing and an undulating sensation all through the system,'.-Sharp pains in the stomach and bowels,.-Pain in the epigastrium, increased by turning in bed,'.-Pain in the epigastrium, increased by drinking water,'.-Soreness in the epigastric region,.

Abdomen.-Flatulency, confined to the stomach,'.-*Sharp pains in the bowels and stomach,3.-Heat and sharp pain in the right side of the abdomen, in the evening,'.-The evacuations from the bowels seemed to proceed from the small intestines,1.

Anus. [30.] Irritation in the anus, with exudation of mucus,2. Stool. The evacuations are most frequent in the evening,'.-Evacuation from the bowels at 7 A.M., preceded by pain in the abdomen,'.-Copious evacuation of thin stools from the bowels, without pain,'.-Stools watery or frothy, voided without pain, and are followed by exhaustion,'.-Stool at 7 A.M., followed by numbness of the lower extremities,1.

Sexual Organs.-Discharge of semen during sleep, without erection,'.

Respiratory Organs.-*Asthmatic troubles,.

Heart.-Audible beating of the heart, and slight pain under the left

breast,'.

Neck and Back.-Pain in the nape, with perspiration,.-[40.] Pain in the nape and back,'.-Pain in the nape and occiput, with coldness and stiffness in the feet,'.-Rheumatic pain in the back from stooping,'.— Pain and stiffness in the loins,'.-The pain in the loins is confined to the left side,'.

Extremities.-Stiffness of all the joints of the upper, as well as of the lower extremities,1.

it,'.

Superior Extremities.-Pain in the right shoulder from lying on

Inferior Extremities.-Remarkable stiffness in the lower extrem

ities, with slight coldness, and a tingling sensation,'.-Stiffness in the knees when attempting to rise,'.-Pain in the right knee,'.-[50.] Drawing and shrinking sensation in the legs, and the most decided pricking in the soles of the feet,'.-Numbness in the calves of the legs,.-Penetrating pain under and behind the left external malleolus, after sleeping,'.-Stiffness of the joints of the toes, ankles, and knees, when lying,'.

Generalities.-Aching in all the bones,'.-Dulness and drowsiness, with disinclination to engage actively in business,'.-It acted promptly and energetically, causing aching pains in nearly every part of the body, especially of the lower limbs and head,3.

Skin.-Vesicular eruption on the forehead, over the left eye, on the middle of the chest, and on the right arm,2.-Violent itching eruption on the skin, generally with elevation of the skin (second day),.-Very great itching at night, with welts all over the surface,.

Sleep.-[60.] Sleepiness, without the ability to sleep sound after mid

night,'.

Fever.-Coldness and stiffness in the feet,'.-Fever,.-Drying away of the perspiration, and development of fever, with hot skin and increased thirst,'.-General perspiration,'.

Conditions.-Aggravation.-(Evening), Heat and pain in right side of abdomen; evacuations. (Midnight), On rising, giddiness. (When lying), Stiffness of joints of toes.-(After sleeping), Pain behind left external malleolus. (Sitting up), Headache. (Stooping), Pain in back.(Turning in bed), Pain in epigastrium.

TROMBIDIUM MUSCE DOMESTICE.

Animal kingdom.
Class, Arachnida.
Order, Acaridea.

Preparation, Tincture of the animals.

Authorities. Jos. P. Harvey, M.D., Hahn. Month. 1, 1865, p. 83; one hundred and fifty were put into 50 drops of alcohol; 1, Dr. Harvey, took 2 drops 3d dec. dil. at 11 P.M. (first day); 2 drops 6th dec. dil. at 11 P.M. (fifth day); 2 drops 9th cent. dil. at 11 P.M. (eleventh day); 2, same, afterwards took 2 drops 12th cent. dil. at 11 P.M. (first day); 3 drops 18th cent. dil. at 11 P.M. (eighth day); 3, Dr. Edwin Heath, took 2 drops 9th cent. atten., symptoms occurred on second and third days; 4, J. F. R., took 2 drops of same at 3 P.M.; 5, E. K. Bancroft, took 2 powders of 30th cent. atten. (first day); took Merc. (twelfth day).

Mind.-Unusually talkative during the day (second day),'.—Talkative during the day, and disposed to be contrary (third day),.-Inability to collect ideas; absence of ideas,.-Loss of memory,3.

Head.-Vertigo. On every attempt to rise from bed felt dizzy and faint, and had to throw myself back on the bed to prevent fainting (seventh day),.—Dizziness of the head from lightness; it felt as if there was no weight in the head,.-General Head. Lightness of the head,3.— During the forenoon a dull feeling through the head (third day),'.--In the evening congestion to the head, with red face and ears (tenth day),".-[10.] Oppressive headache,.-Pulsation in the arteries of the head, with the fever (seventh day),.—Temples. Dull, heavy, sometimes sharp pains in the temples, extending over the frontal regions, felt more severely in left

side (at 9.30 P.M.), (second day),'.-Awoke with pain in the left mastoid process at 7 A.M. (third day),.-Parietals. Dull pain in left side of head, aggravated by shaking the head and walking, at 10 P.M. (fourth day), Shooting pains in the right side of the head, just above the temporal region, at 3 P.M. (fifth day),.-Shooting pain in the right side of head, near the parietal eminence, at 11 A.M. (seventh day),.-Occiput. Dull aching in the occiput, with the fever (seventh day),5.-External Head. Intolerable itching of the scalp, especially the vertex and occiput, at 7 A.M. (fourth day),'.

Eye.-Redness of internal portion of the conjunctiva, similar to a pterygium (twelfth day),".-[20.] Intolerable itching in the inner canthus of the right eye at 9 P.M. (fifth day),'.-Lachrymation in the open air (fourth day),'.

Ear. Quite a burning sensation in the pinnæ of both ears, felt more especially in the right, in the evening (tenth day),2.-Shooting pain in right ear at 3.30 P.M. (third day),'.-Shooting pains in right ear at 3 P.M. (sixth day),'.-Shooting pains in the right ear (thirteenth day),'.-Dull, but occasionally severe shooting pains in right ear, aggravated by swallowing or blowing the nose, in the forenoon (fifth day),.-Shooting pains in both ears, occurring quite frequently, and felt more severely in right one, in the afternoon (eleventh day),.-Severe shooting pains in right ear, frequently during the day and evening (twelfth day),.-Itching in both ears, soon after rising (fifteenth day),2.

Nose. [30.] Mucous discharge from anterior nares, worse while eating dinner (third day),'.—On rising, the nasal passages were much obstructed, but in the afternoon and evening, fluent coryza, especially while eating, and in the open air (fourth day),2.-Fluent coryza, brought on in the open air, and by eating (all through the proving). It gave place in the evening to a dryness and scabs in the nose (fourteenth day),2.-Nosebleed in the morning (ninth day); in the afternoon (tenth day),.

Mouth.-Teeth. Dull toothache all the evening, in a decayed tooth of the left side (thirteenth day),'.-Dull pain in decayed teeth of left side at 11 P.M. (second day),2.-Awoke at 7 A.M. with a toothache in a decayed tooth of left side, pain dull, which having abated somewhat, was renewed by eating breakfast, and continued till noon (fourteenth day),2.—A severe dull pain in a decayed tooth of left side, brought on during the evening, by reading aloud for an hour, and which prevented sleep almost the entire night (twentieth day); it continued on the next day, until evening, when a dose of Staphisagria 200, relieved it; it was aggravated by lying down, by eating, talking, and from cold air; ameliorated by taking some warm drink into the mouth,2-Tongue. Tongue heavily coated with white coating (ninth day ),5.

Throat. Slight soreness in the right side of the throat (fifth day),2. Stomach.-[40.] No appetite (eighth day),.-Eructations after meals, tasting of the ingesta (fourteenth day); lasting an hour after each meal (fifteenth day),2-(Two days after, vomited after breakfast, thought it was from drinking coffee),.-Pain in the pit of the stomach (dull griping), aggravated by eating dinner (twelfth day),'.

Abdomen.-Hypochondria. Dull aching pain in the region of the liver, just under the free ends of the floating ribs, aggravated by pressure, in the forenoon (third day),'.-Sore, dull, aching pain in the region of the liver, just beneath the free ends of the floating ribs, place very sensitive to the touch, in the evening (seventh day),'.-Pain in region of liver,