Addiction

Forsideomslag
Oxford University Press, 23. aug. 2018 - 144 sider
Substance addiction is a chronic, relapsing disorder characterized by a compulsion to take a substance despite potential consequences. Addiction, second edition offers a clear and succinct overview of the brain science underpinning substance addiction. Focusing on the nature of addiction as a brain disorder, this resource discusses a range of different behavioural traits such as impulsivity and reward dependence, and looks at the critical role of kinetic and pharmacological factors. All chapters have been fully updated to provide readers with a quick-reference guide to the latest research on pharmacological and non-pharmacological treatments for addition, and feature helpful key points and further reading sources. In addition, two new chapters on nicotine addiction and appetite hormones have been added to ensure the reader is kept abreast of the most recent discussions in the field of research.
 

Indhold

1 What is addiction?
1
2 Burden of addiction
7
3 Key elements of addiction
17
4 Neurobiological processes in addiction
23
5 Drug pharmacokinetics and abuse liability
31
6 Pharmocodynamics of addictive substances
37
7 The dopamine system and addiction
43
8 The GABA system and addiction
55
9 The glutamate system and addiction
69
10 The opioid system and addiction
79
11 Nicotine addiction
89
12 Appetite hormones and addiction
105
13 Conclusion and overview
117
Index
121
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Om forfatteren (2018)

David J. Nutt is currently the Edmond J. Safra Professor of Neuropsychopharmacology and director of the Neuropsychopharmacology Unit in the Division of Brain Sciences, Imperial College London. Liam J. Nestor is currently a Research Fellow at the Neuropsychopharmacology Unit in the Division of Brain Sciences, Imperial College London.

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